| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.119456 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0963246 |
| SMAD3 | SMAD family member 3 | 0.091463 |
| INTS6 | integrator complex subunit 6 | 0.0839195 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0697854 |
| ANXA2 | annexin A2 | 0.0633886 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0589634 |
| CCNL1 | cyclin L1 | 0.0572525 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.056868 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0545323 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0544151 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0532438 |
| VCL | vinculin | 0.0530305 |
| MUC13 | mucin 13, cell surface associated | 0.0526076 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.052467 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0519172 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0518782 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0512097 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0493943 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0492859 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0463051 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0460784 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0450039 |
| RAD51B | RAD51 paralog B | 0.0448715 |
| RNF43 | ring finger protein 43 | 0.0447206 |
| PGK1 | phosphoglycerate kinase 1 | 0.0445908 |
| EFNB2 | ephrin-B2 | 0.0445188 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0441241 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0436297 |
| FNIP1 | folliculin interacting protein 1 | 0.0422902 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0421696 |
| YAP1 | Yes-associated protein 1 | 0.0410009 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0406259 |
| ZNF292 | zinc finger protein 292 | 0.0406104 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0405122 |
| ERBIN | erbb2 interacting protein | 0.0405055 |
| PDZD8 | PDZ domain containing 8 | 0.0391964 |
| ZNF207 | zinc finger protein 207 | 0.0385587 |
| MAP7 | microtubule-associated protein 7 | 0.0381129 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.037742 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.036098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0358041 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0355706 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0350248 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0349948 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0349922 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0346997 |
| TC2N | tandem C2 domains, nuclear | 0.0343381 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0339044 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0335277 |
| STK24 | serine/threonine kinase 24 | 0.0333295 |
| CD68 | CD68 molecule | 0.0332267 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0322822 |
| FOXO3 | forkhead box O3 | 0.0321784 |
| ATP11A | ATPase, class VI, type 11A | 0.0319803 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0309273 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0304541 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0300625 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0298365 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.029821 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.029629 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0295779 |
| PLSCR2 | phospholipid scramblase 2 | 0.029215 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292081 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0291081 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0284658 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0283632 |
| EGR1 | early growth response 1 | 0.0279948 |
| RNF213 | ring finger protein 213 | 0.0279745 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0276378 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0275801 |
| FAT1 | FAT atypical cadherin 1 | 0.0273034 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269981 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0269516 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0266717 |
| MLPH | melanophilin | 0.0264387 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0263364 |
| NCKAP5 | NCK-associated protein 5 | 0.0257478 |
| PRKCA | protein kinase C, alpha | 0.0255127 |
| MYO10 | myosin X | 0.0252243 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.02502 |
| SERINC5 | serine incorporator 5 | 0.0247902 |
| PLSCR1 | phospholipid scramblase 1 | 0.024397 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0243783 |
| LMO7 | LIM domain 7 | 0.0239889 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0238714 |
| ATOSA | atos homolog A | 0.0238166 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0235804 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0234981 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0229242 |
| MEIS2 | Meis homeobox 2 | 0.0228887 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0225335 |
| IFNGR1 | interferon gamma receptor 1 | 0.0225211 |
| KYNU | kynureninase | 0.0223935 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0223446 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.0220829 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0217432 |
| TMEM62 | transmembrane protein 62 | 0.0217111 |
| PKM | pyruvate kinase, muscle | 0.0216248 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0214794 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.236581 |
| PTMA | prothymosin, alpha | -0.160209 |
| B2M | beta-2-microglobulin | -0.125243 |
| LCN2 | lipocalin 2 | -0.120138 |
| HLA-B | major histocompatibility complex, class I, B | -0.109479 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.103645 |
| FTL | ferritin, light polypeptide | -0.0986128 |
| LYZ | lysozyme | -0.0947938 |
| TMSB10 | thymosin beta 10 | -0.0851532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0768118 |
| EZR | ezrin | -0.0692484 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0600336 |
| RPS6 | ribosomal protein S6 | -0.0591427 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0581955 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0579944 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0576805 |
| RPL19 | ribosomal protein L19 | -0.0553013 |
| EPCAM | epithelial cell adhesion molecule | -0.0529462 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0528789 |
| ENO1 | enolase 1, (alpha) | -0.0526433 |
| RPL35A | ribosomal protein L35a | -0.051991 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0517252 |
| PERP | PERP, TP53 apoptosis effector | -0.0510836 |
| ITGA6 | integrin, alpha 6 | -0.0506596 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.049786 |
| RPS24 | ribosomal protein S24 | -0.049457 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0491938 |
| RPLP1 | ribosomal protein, large, P1 | -0.0459468 |
| RRBP1 | ribosome binding protein 1 | -0.0452451 |
| RPL34 | ribosomal protein L34 | -0.0448245 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0446818 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0426855 |
| RPS8 | ribosomal protein S8 | -0.0413217 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0403673 |
| RPS3 | ribosomal protein S3 | -0.0390318 |
| RPL31 | ribosomal protein L31 | -0.0368246 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0367032 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0366662 |
| RPL12 | ribosomal protein L12 | -0.036499 |
| RPL37A | ribosomal protein L37a | -0.0362712 |
| CST3 | cystatin C | -0.0355158 |
| RPL26 | ribosomal protein L26 | -0.035244 |
| RPL11 | ribosomal protein L11 | -0.0351091 |
| S100A10 | S100 calcium binding protein A10 | -0.0350499 |
| CANX | calnexin | -0.0350354 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0342597 |
| APOL1 | apolipoprotein L, 1 | -0.0334585 |
| RPL23 | ribosomal protein L23 | -0.0319428 |
| S100A6 | S100 calcium binding protein A6 | -0.0318795 |
| NDRG1 | N-myc downstream regulated 1 | -0.0315172 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0314961 |
| HLA-E | major histocompatibility complex, class I, E | -0.0314282 |
| HLA-C | major histocompatibility complex, class I, C | -0.0314152 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0313062 |
| DSTN | destrin (actin depolymerizing factor) | -0.0312636 |
| HMGB1 | high mobility group box 1 | -0.0312126 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0309349 |
| TPI1 | triosephosphate isomerase 1 | -0.0306818 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.03058 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0305767 |
| H3-3B | H3.3 histone B | -0.0303922 |
| RPS17 | ribosomal protein S17 | -0.0301823 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0299226 |
| DEK | DEK proto-oncogene | -0.0298179 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0297817 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0294282 |
| SERF2 | small EDRK-rich factor 2 | -0.0294157 |
| IRF1 | interferon regulatory factor 1 | -0.0290278 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.028933 |
| ABLIM1 | actin binding LIM protein 1 | -0.0286688 |
| RPL32 | ribosomal protein L32 | -0.0283689 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0280691 |
| RPS19 | ribosomal protein S19 | -0.0274231 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0274063 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0272499 |
| CDK6 | cyclin-dependent kinase 6 | -0.0271607 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0270716 |
| UBC | ubiquitin C | -0.0269924 |
| HLA-A | major histocompatibility complex, class I, A | -0.026938 |
| LMNA | lamin A/C | -0.0267749 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0266994 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.026684 |
| CALR | calreticulin | -0.0265047 |
| TMC5 | transmembrane channel-like 5 | -0.0265014 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0264451 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0264442 |
| MATR3 | matrin 3 | -0.0263468 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0261242 |
| JUN | jun proto-oncogene | -0.0260144 |
| WDR45B | WD repeat domain 45B | -0.0258714 |
| RPL7A | ribosomal protein L7a | -0.0257994 |
| AHI1 | Abelson helper integration site 1 | -0.025766 |
| IER3 | immediate early response 3 | -0.0257203 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0256035 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0253724 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0252172 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0251123 |
| HDLBP | high density lipoprotein binding protein | -0.0247096 |
| JMJD1C | jumonji domain containing 1C | -0.0245374 |
| CCNI | cyclin I | -0.0244836 |
