| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.410473 |
| COL6A3 | collagen, type VI, alpha 3 | 0.175787 |
| CADM1 | cell adhesion molecule 1 | 0.124675 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.118852 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0973494 |
| NDRG1 | N-myc downstream regulated 1 | 0.096633 |
| ATP13A3 | ATPase type 13A3 | 0.0932565 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0859332 |
| LOXL2 | lysyl oxidase-like 2 | 0.0787219 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0782623 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0718692 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0681369 |
| LDHA | lactate dehydrogenase A | 0.0648253 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0587699 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0578597 |
| FLNA | filamin A, alpha | 0.0575862 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0574069 |
| CD44 | CD44 molecule (Indian blood group) | 0.0522597 |
| ARRDC3 | arrestin domain containing 3 | 0.0494175 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0478648 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0477734 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0449442 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0448785 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0430401 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0418687 |
| NAV2 | neuron navigator 2 | 0.0416648 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0411823 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.04093 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0408481 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0403002 |
| SMAD3 | SMAD family member 3 | 0.0399185 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0396596 |
| PGK1 | phosphoglycerate kinase 1 | 0.0392491 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0391273 |
| PTK2 | protein tyrosine kinase 2 | 0.0380371 |
| SPAG9 | sperm associated antigen 9 | 0.0373911 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0370637 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0365573 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0352852 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0346275 |
| FMNL2 | formin-like 2 | 0.0311903 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0310584 |
| CANX | calnexin | 0.0310516 |
| PDE10A | phosphodiesterase 10A | 0.0302906 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0295496 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.029528 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0295087 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0294914 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0294401 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0289057 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0287797 |
| ENO1 | enolase 1, (alpha) | 0.0287485 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0286131 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0284646 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0273951 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0273423 |
| POSTN | periostin, osteoblast specific factor | 0.0269926 |
| FAT1 | FAT atypical cadherin 1 | 0.0268074 |
| YEATS2 | YEATS domain containing 2 | 0.0267385 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0263272 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0262597 |
| IL6ST | interleukin 6 signal transducer | 0.0262545 |
| MTSS1 | metastasis suppressor 1 | 0.0261391 |
| PKM | pyruvate kinase, muscle | 0.0260837 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0260561 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0256971 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0255515 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0252052 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0251785 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0249081 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.024654 |
| GANAB | glucosidase, alpha; neutral AB | 0.0246109 |
| RND3 | Rho family GTPase 3 | 0.0244907 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0243305 |
| HIP1 | huntingtin interacting protein 1 | 0.0241012 |
| RASA2 | RAS p21 protein activator 2 | 0.0240791 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0240714 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0238241 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0237867 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.023606 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0235149 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0231948 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.023131 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0230172 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0225987 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0225936 |
| RLF | rearranged L-myc fusion | 0.0224311 |
| ANXA2 | annexin A2 | 0.0220494 |
| RPN1 | ribophorin I | 0.0220427 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0220196 |
| RBM39 | RNA binding motif protein 39 | 0.0220051 |
| ZNF292 | zinc finger protein 292 | 0.0219474 |
| RTN4 | reticulon 4 | 0.0219391 |
| USP3 | ubiquitin specific peptidase 3 | 0.0219033 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0217738 |
| RUNX1 | runt-related transcription factor 1 | 0.0216851 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.021585 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0214871 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0212996 |
| CALR | calreticulin | 0.0209651 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.35731 |
| MT2A | metallothionein 2A | -0.135395 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112546 |
| TMSB10 | thymosin beta 10 | -0.107117 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0864079 |
| VIM | vimentin | -0.0825312 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0781235 |
| GLIS3 | GLIS family zinc finger 3 | -0.0634935 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.063299 |
| FTL | ferritin, light polypeptide | -0.0625489 |
| COL1A1 | collagen, type I, alpha 1 | -0.0619792 |
| PALLD | palladin, cytoskeletal associated protein | -0.0567271 |
| COL1A2 | collagen, type I, alpha 2 | -0.0502658 |
| VEGFA | vascular endothelial growth factor A | -0.0492541 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0456833 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.040674 |
| B2M | beta-2-microglobulin | -0.0399436 |
| VCL | vinculin | -0.0384205 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.036079 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0355879 |
| RPL35A | ribosomal protein L35a | -0.033132 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0329932 |
| RPS6 | ribosomal protein S6 | -0.0327001 |
| EGR1 | early growth response 1 | -0.0315741 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.031182 |
| RPS8 | ribosomal protein S8 | -0.0306519 |
| HLA-B | major histocompatibility complex, class I, B | -0.0303205 |
| LIMA1 | LIM domain and actin binding 1 | -0.030038 |
| HLA-A | major histocompatibility complex, class I, A | -0.0295941 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0291828 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0286276 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0280495 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0272289 |
| ZNF644 | zinc finger protein 644 | -0.0271853 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.027032 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0260647 |
| STC1 | stanniocalcin 1 | -0.0255354 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0255236 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0255208 |
| VMP1 | vacuole membrane protein 1 | -0.0250877 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0248852 |
| MT1X | metallothionein 1X | -0.0246241 |
| RSU1 | Ras suppressor protein 1 | -0.024345 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.024336 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0242917 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0240463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.023379 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0233007 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0231289 |
| TMF1 | TATA element modulatory factor 1 | -0.0228122 |
| ATM | ATM serine/threonine kinase | -0.0227342 |
| NABP1 | nucleic acid binding protein 1 | -0.0225799 |
| CALD1 | caldesmon 1 | -0.0223609 |
| GOLGB1 | golgin B1 | -0.0223554 |
| S100A10 | S100 calcium binding protein A10 | -0.0220707 |
| COG5 | component of oligomeric golgi complex 5 | -0.022033 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0215251 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0213415 |
| WRN | Werner syndrome, RecQ helicase-like | -0.0212323 |
| S100A9 | S100 calcium binding protein A9 | -0.0212145 |
| DST | dystonin | -0.0210156 |
| RPS14 | ribosomal protein S14 | -0.0210016 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0208651 |
| HMGA2 | high mobility group AT-hook 2 | -0.0206756 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0202761 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.020009 |
| RPS19 | ribosomal protein S19 | -0.0196269 |
| CNTN5 | contactin 5 | -0.0195179 |
| RPL28 | ribosomal protein L28 | -0.0195005 |
| TPM1 | tropomyosin 1 (alpha) | -0.0194237 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0193803 |
| CLMP | CXADR-like membrane protein | -0.0193214 |
| TPM4 | tropomyosin 4 | -0.0192491 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0191049 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0188694 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0187645 |
| TXNRD1 | thioredoxin reductase 1 | -0.0183924 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0179174 |
| CSPP1 | centrosome and spindle pole associated protein 1 | -0.0176499 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0174584 |
| RPL31 | ribosomal protein L31 | -0.0174022 |
| RPL8 | ribosomal protein L8 | -0.017334 |
| RPL36 | ribosomal protein L36 | -0.0172987 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0172426 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0172255 |
| INTS6 | integrator complex subunit 6 | -0.0170577 |
| BPTF | bromodomain PHD finger transcription factor | -0.0170072 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0169682 |
| EXOC6B | exocyst complex component 6B | -0.0168219 |
| NEK11 | NIMA-related kinase 11 | -0.01678 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0167551 |
| INHBA | inhibin, beta A | -0.0167286 |
| RPL32 | ribosomal protein L32 | -0.0166761 |
| SQLE | squalene epoxidase | -0.0166539 |
| KIAA1328 | KIAA1328 | -0.0165026 |
| CST3 | cystatin C | -0.0165009 |
| AHI1 | Abelson helper integration site 1 | -0.0163108 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0162852 |
| OFD1 | oral-facial-digital syndrome 1 | -0.016201 |
| GLG1 | golgi glycoprotein 1 | -0.016196 |
