| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.19443 |
| IGF2 | insulin-like growth factor 2 | 0.139255 |
| SLC38A2 | solute carrier family 38, member 2 | 0.128882 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.127196 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.107584 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0892269 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0881392 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0869884 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0859357 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0774859 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0736919 |
| ITGAV | integrin, alpha V | 0.0649244 |
| VCL | vinculin | 0.0599893 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0598742 |
| ASPH | aspartate beta-hydroxylase | 0.0561318 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0551275 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0547762 |
| ATXN1 | ataxin 1 | 0.0545687 |
| FLNB | filamin B, beta | 0.0517357 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.050775 |
| FAM107B | family with sequence similarity 107, member B | 0.0507227 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0490911 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0480969 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0475028 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0471383 |
| DST | dystonin | 0.0470825 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0455262 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.044029 |
| CCNL1 | cyclin L1 | 0.0433696 |
| BCL2L1 | BCL2-like 1 | 0.0427323 |
| FAT1 | FAT atypical cadherin 1 | 0.0416351 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0416076 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0413012 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0385195 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0382454 |
| SVIL | supervillin | 0.0379946 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0377324 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0373905 |
| ANXA5 | annexin A5 | 0.0370634 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0363684 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0361618 |
| DTNA | dystrobrevin, alpha | 0.0357834 |
| HMGA1 | high mobility group AT-hook 1 | 0.0355491 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0353392 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0352541 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0351537 |
| TNS1 | tensin 1 | 0.0350531 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | 0.0348456 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0348406 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0337856 |
| SIK3 | SIK family kinase 3 | 0.0336548 |
| MYO1B | myosin IB | 0.0333322 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0332706 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0331053 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0323757 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0323174 |
| DIAPH1 | diaphanous-related formin 1 | 0.0321272 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.031936 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0315898 |
| ENAH | enabled homolog (Drosophila) | 0.0309492 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0307693 |
| LDHA | lactate dehydrogenase A | 0.030318 |
| TF | transferrin | 0.0302277 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0299793 |
| FOXO1 | forkhead box O1 | 0.0295344 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0293261 |
| RPL4 | ribosomal protein L4 | 0.0292661 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0291564 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0290976 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0290938 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0289195 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0281266 |
| VEGFA | vascular endothelial growth factor A | 0.028092 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0280758 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.028057 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0278267 |
| USP34 | ubiquitin specific peptidase 34 | 0.0276285 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0275847 |
| TRIM24 | tripartite motif containing 24 | 0.0274895 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0269793 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0267104 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0263959 |
| FERMT2 | fermitin family member 2 | 0.0261547 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0257729 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.0257174 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0254033 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0250304 |
| JAG1 | jagged 1 | 0.0249279 |
| CLTC | clathrin, heavy chain (Hc) | 0.0249196 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0247669 |
| NPTN | neuroplastin | 0.0247103 |
| SERTAD2 | SERTA domain containing 2 | 0.0245259 |
| NUP58 | nucleoporin 58 | 0.0245086 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0244515 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0240471 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0239107 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0238601 |
| FLNA | filamin A, alpha | 0.0236528 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.023587 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0235227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.127002 |
| APOB | apolipoprotein B | -0.116428 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0900744 |
| RPS8 | ribosomal protein S8 | -0.0794257 |
| GPC3 | glypican 3 | -0.0715984 |
| FTL | ferritin, light polypeptide | -0.0669284 |
| APOA2 | apolipoprotein A-II | -0.0645151 |
| TMSB10 | thymosin beta 10 | -0.0634705 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0628409 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0605063 |
| RPS24 | ribosomal protein S24 | -0.0599814 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0574962 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0566887 |
| RPS12 | ribosomal protein S12 | -0.0537561 |
| RPS6 | ribosomal protein S6 | -0.0519177 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0498314 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0492456 |
| APOE | apolipoprotein E | -0.0486083 |
| RPL31 | ribosomal protein L31 | -0.0485229 |
| PTMA | prothymosin, alpha | -0.0477358 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0460928 |
| TRIM26 | tripartite motif containing 26 | -0.0419619 |
| PEG3 | paternally expressed 3 | -0.0416486 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.041009 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0409995 |
| ENO1 | enolase 1, (alpha) | -0.0377317 |
| LYZ | lysozyme | -0.0376401 |
| EHBP1 | EH domain binding protein 1 | -0.037475 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0371813 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0360872 |
| RPL37A | ribosomal protein L37a | -0.0359043 |
| RPS19 | ribosomal protein S19 | -0.0355652 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0352616 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0350039 |
| RRBP1 | ribosome binding protein 1 | -0.0343295 |
| DSPP | dentin sialophosphoprotein | -0.0334568 |
| IER3 | immediate early response 3 | -0.0333234 |
| RPS27A | ribosomal protein S27a | -0.0329165 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0327507 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0322112 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0321202 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0320663 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0319853 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0308223 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0304793 |
| RPLP1 | ribosomal protein, large, P1 | -0.0297706 |
| RPL34 | ribosomal protein L34 | -0.0296049 |
| RPS17 | ribosomal protein S17 | -0.0295873 |
| CANX | calnexin | -0.029395 |
| A2M | alpha-2-macroglobulin | -0.0289713 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0285492 |
| RPL23 | ribosomal protein L23 | -0.02784 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0278166 |
| BPTF | bromodomain PHD finger transcription factor | -0.0274816 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0272204 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0271364 |
| RPL32 | ribosomal protein L32 | -0.0271189 |
| RPL35A | ribosomal protein L35a | -0.0270126 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.0269893 |
| PERP | PERP, TP53 apoptosis effector | -0.0266634 |
| RNF149 | ring finger protein 149 | -0.0260176 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0256713 |
| RPS5 | ribosomal protein S5 | -0.0255889 |
| RPL26 | ribosomal protein L26 | -0.0254956 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0254433 |
| RPL5 | ribosomal protein L5 | -0.0254411 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0253483 |
| RPL19 | ribosomal protein L19 | -0.0253418 |
| RPLP2 | ribosomal protein, large, P2 | -0.0251859 |
| CP | ceruloplasmin (ferroxidase) | -0.0251588 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0246805 |
| SYN3 | synapsin III | -0.0242474 |
| MATR3 | matrin 3 | -0.0235964 |
| RPS29 | ribosomal protein S29 | -0.0234244 |
| NPR2 | natriuretic peptide receptor 2 | -0.0233719 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0232886 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0232547 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0232426 |
| HLF | hepatic leukemia factor | -0.0229686 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0227184 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.02266 |
| FABP1 | fatty acid binding protein 1, liver | -0.0226459 |
| RPL12 | ribosomal protein L12 | -0.0224336 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0222752 |
| TPM4 | tropomyosin 4 | -0.0222014 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.022087 |
| KIAA1217 | KIAA1217 | -0.021973 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.021944 |
| RPS21 | ribosomal protein S21 | -0.0217689 |
| RPS25 | ribosomal protein S25 | -0.0217649 |
| B2M | beta-2-microglobulin | -0.0216838 |
| RPLP0 | ribosomal protein, large, P0 | -0.0215175 |
| TMEM181 | transmembrane protein 181 | -0.0212926 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0211903 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0210465 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0208753 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0208267 |
| TMEM51 | transmembrane protein 51 | -0.020697 |
| BPIFB2 | BPI fold containing family B, member 2 | -0.020669 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.0206683 |
