| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.251071 |
| FLNB | filamin B, beta | 0.152406 |
| PODXL | podocalyxin-like | 0.140077 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.112005 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.103186 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0997983 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0917302 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0883375 |
| FOXO1 | forkhead box O1 | 0.0815831 |
| FLNA | filamin A, alpha | 0.0812683 |
| MTSS1 | metastasis suppressor 1 | 0.0755676 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0725825 |
| LDHA | lactate dehydrogenase A | 0.0722597 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0680159 |
| LAMA5 | laminin, alpha 5 | 0.066335 |
| PALLD | palladin, cytoskeletal associated protein | 0.0660666 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0655931 |
| PGK1 | phosphoglycerate kinase 1 | 0.0650021 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0618622 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0617889 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0597266 |
| TGM2 | transglutaminase 2 | 0.0578996 |
| PLS3 | plastin 3 | 0.053596 |
| EGR1 | early growth response 1 | 0.0532281 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0517893 |
| LMO7 | LIM domain 7 | 0.0500425 |
| SULF2 | sulfatase 2 | 0.0474218 |
| GRB10 | growth factor receptor-bound protein 10 | 0.047397 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0472195 |
| RASAL2 | RAS protein activator like 2 | 0.0472126 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0457312 |
| STC1 | stanniocalcin 1 | 0.0453126 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0445331 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0443821 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0439842 |
| KRT17 | keratin 17, type I | 0.0436581 |
| EPHA2 | EPH receptor A2 | 0.0434094 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0413263 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0397472 |
| AMOTL1 | angiomotin like 1 | 0.038878 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0385649 |
| C1D | C1D nuclear receptor corepressor | 0.0383352 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0371981 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0349621 |
| MXRA5 | matrix-remodelling associated 5 | 0.034287 |
| ITGB4 | integrin, beta 4 | 0.0341848 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0341007 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0331356 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0328965 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0320725 |
| OSMR | oncostatin M receptor | 0.0319134 |
| RCOR1 | REST corepressor 1 | 0.0315847 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0312056 |
| NAV2 | neuron navigator 2 | 0.0308711 |
| MEGF6 | multiple EGF-like-domains 6 | 0.030742 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0299976 |
| AOPEP | aminopeptidase O (putative) | 0.029661 |
| GPR176 | G protein-coupled receptor 176 | 0.0294744 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0293655 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0293208 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0289307 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0278977 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0277795 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0276431 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0273854 |
| TJP1 | tight junction protein 1 | 0.0271955 |
| FAM107B | family with sequence similarity 107, member B | 0.0271431 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0270459 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.026249 |
| LRRC8A | leucine rich repeat containing 8 family, member A | 0.0260435 |
| VCL | vinculin | 0.0259945 |
| LUZP1 | leucine zipper protein 1 | 0.0259339 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0258541 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0257943 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0254766 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0250502 |
| MYADM | myeloid-associated differentiation marker | 0.0248478 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0248339 |
| IGF2 | insulin-like growth factor 2 | 0.0247014 |
| RNF217 | ring finger protein 217 | 0.0244253 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0242478 |
| CAV2 | caveolin 2 | 0.0240368 |
| CD44 | CD44 molecule (Indian blood group) | 0.0239162 |
| EFHD2 | EF-hand domain family, member D2 | 0.0237591 |
| ACTN4 | actinin, alpha 4 | 0.0236054 |
| ANXA2 | annexin A2 | 0.0235184 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0234007 |
| DHFR | dihydrofolate reductase | 0.0233095 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0230588 |
| GANAB | glucosidase, alpha; neutral AB | 0.0226281 |
| PLEC | plectin | 0.0226137 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0224643 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0224635 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0222681 |
| WASF2 | WAS protein family, member 2 | 0.0221541 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0221308 |
| KIAA1671 | KIAA1671 | 0.0217755 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0215046 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0213089 |
| PLXNA2 | plexin A2 | 0.0211507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | -0.109498 |
| PTMA | prothymosin, alpha | -0.087512 |
| ASPH | aspartate beta-hydroxylase | -0.0829673 |
| TMSB4X | thymosin beta 4, X-linked | -0.0775416 |
| AHNAK | AHNAK nucleoprotein | -0.0772829 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0769277 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0763826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0736542 |
| ITGA6 | integrin, alpha 6 | -0.067805 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0646437 |
| CANX | calnexin | -0.0633685 |
| TMSB10 | thymosin beta 10 | -0.0632513 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0613931 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0603369 |
| CUL4B | cullin 4B | -0.0603035 |
| NDRG1 | N-myc downstream regulated 1 | -0.05925 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0557252 |
| MEF2A | myocyte enhancer factor 2A | -0.0536525 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0526325 |
| DSTN | destrin (actin depolymerizing factor) | -0.0522736 |
| RPS8 | ribosomal protein S8 | -0.0511127 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0500443 |
| RBM39 | RNA binding motif protein 39 | -0.0492302 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0490624 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0482445 |
| OGA | O-GlcNAcase | -0.0478984 |
| LMNA | lamin A/C | -0.0469804 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0460476 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0459039 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.043766 |
| GOLGA4 | golgin A4 | -0.0436216 |
| EZR | ezrin | -0.0434062 |
| SERINC3 | serine incorporator 3 | -0.0430002 |
| RAI14 | retinoic acid induced 14 | -0.0429058 |
| ANXA1 | annexin A1 | -0.0426543 |
| RPS3 | ribosomal protein S3 | -0.0426257 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0426057 |
| TPM3 | tropomyosin 3 | -0.0423319 |
| ZNF292 | zinc finger protein 292 | -0.0417019 |
| ANLN | anillin, actin binding protein | -0.0413291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0402484 |
| EMP1 | epithelial membrane protein 1 | -0.039229 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0392037 |
| MYOF | myoferlin | -0.0386245 |
| MATR3 | matrin 3 | -0.0383978 |
| RPS6 | ribosomal protein S6 | -0.0374389 |
| RPS24 | ribosomal protein S24 | -0.037438 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0372505 |
| RLF | rearranged L-myc fusion | -0.0359363 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0357551 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0357134 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.035586 |
| TOP1 | topoisomerase (DNA) I | -0.0355698 |
| RPS12 | ribosomal protein S12 | -0.0350644 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0347053 |
| TXNRD1 | thioredoxin reductase 1 | -0.0345419 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0339285 |
| RPLP2 | ribosomal protein, large, P2 | -0.0328886 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0320912 |
| FOXP1 | forkhead box P1 | -0.0319755 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0319249 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0316313 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0315566 |
| SET | SET nuclear proto-oncogene | -0.0313667 |
| S100A10 | S100 calcium binding protein A10 | -0.0310848 |
| FTL | ferritin, light polypeptide | -0.030702 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0301366 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0301313 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0300204 |
| ENO1 | enolase 1, (alpha) | -0.0299961 |
| PTK2 | protein tyrosine kinase 2 | -0.0296683 |
| RPL7A | ribosomal protein L7a | -0.0294473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0294453 |
| XPO1 | exportin 1 | -0.0292463 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0291627 |
| RPL31 | ribosomal protein L31 | -0.0290175 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.029009 |
| YBX1 | Y box binding protein 1 | -0.0289642 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0288037 |
| TPX2 | TPX2, microtubule-associated | -0.0283446 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0283062 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0281986 |
| RPL5 | ribosomal protein L5 | -0.028121 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0279269 |
| RPS27A | ribosomal protein S27a | -0.0278278 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0277158 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0276696 |
| SUCO | SUN domain containing ossification factor | -0.0276257 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0272889 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0271941 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0270353 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0266127 |
| RPL7 | ribosomal protein L7 | -0.0260717 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0260679 |
| TXNIP | thioredoxin interacting protein | -0.0259039 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0258149 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0256768 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0256495 |
| SEPTIN7 | septin 7 | -0.0252994 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0252779 |