| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.11848 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.107375 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0855165 |
| PGK1 | phosphoglycerate kinase 1 | 0.0740019 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0730754 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0630691 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0628586 |
| LDHA | lactate dehydrogenase A | 0.0554778 |
| PKM | pyruvate kinase, muscle | 0.0474992 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0437337 |
| FLNB | filamin B, beta | 0.0428225 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0391286 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0385807 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0367131 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0366877 |
| MUC13 | mucin 13, cell surface associated | 0.0366862 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0366695 |
| ONECUT3 | one cut homeobox 3 | 0.0358436 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0355325 |
| FOXO1 | forkhead box O1 | 0.0330292 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0323267 |
| MYO1E | myosin IE | 0.0319774 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.031515 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0313478 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0305823 |
| CLTC | clathrin, heavy chain (Hc) | 0.0286865 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0275994 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0275131 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0267284 |
| LMO7 | LIM domain 7 | 0.026388 |
| H1-0 | H1.0 linker histone | 0.025954 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0249774 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0245004 |
| CCNL1 | cyclin L1 | 0.024004 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0232659 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0230703 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0229693 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0220782 |
| MED13 | mediator complex subunit 13 | 0.0212209 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0208243 |
| ACTN4 | actinin, alpha 4 | 0.020757 |
| GANAB | glucosidase, alpha; neutral AB | 0.020619 |
| PRSS3 | protease, serine, 3 | 0.020409 |
| RPS2 | ribosomal protein S2 | 0.0202532 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0202001 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0197764 |
| MXD1 | MAX dimerization protein 1 | 0.0194413 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0193691 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0191911 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0181237 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0180324 |
| PLXNB2 | plexin B2 | 0.0177191 |
| NEBL | nebulette | 0.0176802 |
| RNF43 | ring finger protein 43 | 0.0173868 |
| DNM2 | dynamin 2 | 0.0173865 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0173203 |
| HMGA1 | high mobility group AT-hook 1 | 0.017216 |
| RCOR1 | REST corepressor 1 | 0.0171891 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0171581 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0171534 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0171199 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0169755 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0169003 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0167198 |
| BMP4 | bone morphogenetic protein 4 | 0.0166142 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.016512 |
| FLNA | filamin A, alpha | 0.0163815 |
| TMEM45B | transmembrane protein 45B | 0.0162367 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0160832 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0160742 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.015943 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0158267 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0157806 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0157648 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0157394 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0157219 |
| FBXO34 | F-box protein 34 | 0.0154794 |
| NBAS | neuroblastoma amplified sequence | 0.0152275 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0151878 |
| RPL13A | ribosomal protein L13a | 0.0150866 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0150348 |
| SF1 | splicing factor 1 | 0.0150012 |
| RPL4 | ribosomal protein L4 | 0.0149069 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0149062 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.014728 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0146052 |
| RAB10 | RAB10, member RAS oncogene family | 0.0145126 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0144808 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0143463 |
| CTSB | cathepsin B | 0.0142566 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0142554 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0142395 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0141873 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0141284 |
| CD44 | CD44 molecule (Indian blood group) | 0.0141261 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0140882 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | 0.0140711 |
| SGMS1 | sphingomyelin synthase 1 | 0.0140273 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0139892 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0139163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.201579 |
| TMSB10 | thymosin beta 10 | -0.15532 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.139114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0948886 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0881829 |
| EZR | ezrin | -0.0669007 |
| FTL | ferritin, light polypeptide | -0.0628798 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0627782 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0591215 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0580278 |
| TPM4 | tropomyosin 4 | -0.0541044 |
| TXNIP | thioredoxin interacting protein | -0.0530276 |
| NPSR1 | neuropeptide S receptor 1 | -0.0469608 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0449981 |
| RPS8 | ribosomal protein S8 | -0.0427994 |
| NDRG1 | N-myc downstream regulated 1 | -0.0417769 |
| RPS12 | ribosomal protein S12 | -0.038848 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0384447 |
| RPL31 | ribosomal protein L31 | -0.0359009 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0354113 |
| RPS3 | ribosomal protein S3 | -0.0353198 |
| AHNAK | AHNAK nucleoprotein | -0.0350317 |
| RPS6 | ribosomal protein S6 | -0.0348198 |
| S100A10 | S100 calcium binding protein A10 | -0.0339821 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.033421 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0329993 |
| YBX1 | Y box binding protein 1 | -0.0328545 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0325814 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0306714 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0298915 |
| RPL5 | ribosomal protein L5 | -0.0296298 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0295129 |
| RPS24 | ribosomal protein S24 | -0.0294642 |
| MLEC | malectin | -0.0294356 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0280005 |
| CANX | calnexin | -0.0278013 |
| RPS17 | ribosomal protein S17 | -0.0275985 |
| RPS27A | ribosomal protein S27a | -0.0269393 |
| VCL | vinculin | -0.0256883 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0255997 |
| GPHN | gephyrin | -0.0251242 |
| RPL7A | ribosomal protein L7a | -0.0249452 |
| ITGA6 | integrin, alpha 6 | -0.0248048 |
| PERP | PERP, TP53 apoptosis effector | -0.0239999 |
| RPS19 | ribosomal protein S19 | -0.0230844 |
| RPL32 | ribosomal protein L32 | -0.0230427 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0228918 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0227669 |
| RPL19 | ribosomal protein L19 | -0.0227358 |
| RPLP1 | ribosomal protein, large, P1 | -0.0225788 |
| FHIT | fragile histidine triad | -0.0225482 |
| RPL12 | ribosomal protein L12 | -0.0221633 |
| DSTN | destrin (actin depolymerizing factor) | -0.0216884 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0215028 |
| RPL37A | ribosomal protein L37a | -0.0213203 |
| RPLP2 | ribosomal protein, large, P2 | -0.0209632 |
| FNBP1L | formin binding protein 1-like | -0.0203128 |
| RPL21 | ribosomal protein L21 | -0.0201059 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0200787 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0200302 |
| IER3 | immediate early response 3 | -0.0196507 |
| EPCAM | epithelial cell adhesion molecule | -0.019458 |
| RPL26 | ribosomal protein L26 | -0.0189823 |
| ANXA1 | annexin A1 | -0.0185058 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0183901 |
| ENO1 | enolase 1, (alpha) | -0.0182975 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0180931 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0180917 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0179491 |
| RPS25 | ribosomal protein S25 | -0.017876 |
| AGR2 | anterior gradient 2 | -0.0178541 |
| JUN | jun proto-oncogene | -0.0178162 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0173948 |
| DIAPH2 | diaphanous-related formin 2 | -0.0173357 |
| JMJD1C | jumonji domain containing 1C | -0.0172462 |
| TFG | TRK-fused gene | -0.0171917 |
| CBX3 | chromobox homolog 3 | -0.0169466 |
| MATR3 | matrin 3 | -0.0168052 |
| RPS5 | ribosomal protein S5 | -0.016485 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0162325 |
| PCM1 | pericentriolar material 1 | -0.0161706 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0161627 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0161049 |
| LMNA | lamin A/C | -0.0160677 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0153526 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0153249 |
| TES | testin LIM domain protein | -0.0152742 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0151918 |
| RYBP | RING1 and YY1 binding protein | -0.0151751 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0151733 |
| DSPP | dentin sialophosphoprotein | -0.0146463 |
| DEK | DEK proto-oncogene | -0.0146437 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0145247 |
| CCNY | cyclin Y | -0.0142955 |
| TMSB4X | thymosin beta 4, X-linked | -0.014236 |
| SEPTIN7 | septin 7 | -0.0140985 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0138995 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0138864 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0136792 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0136045 |
