| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.239078 |
| CD44 | CD44 molecule (Indian blood group) | 0.112642 |
| SLC38A2 | solute carrier family 38, member 2 | 0.107968 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.095898 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.087793 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0814322 |
| RAI1 | retinoic acid induced 1 | 0.0716349 |
| PGK1 | phosphoglycerate kinase 1 | 0.0656467 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0627662 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0616845 |
| CAPRIN2 | caprin family member 2 | 0.0592302 |
| FMNL2 | formin-like 2 | 0.0587937 |
| DST | dystonin | 0.0584681 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0563021 |
| RUNX1 | runt-related transcription factor 1 | 0.0548521 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0540521 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0530051 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0527421 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0523901 |
| TSC22D1 | TSC22 domain family, member 1 | 0.051697 |
| LOXL2 | lysyl oxidase-like 2 | 0.0497841 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0491251 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0490829 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0488548 |
| POTEF | POTE ankyrin domain family, member F | 0.0485238 |
| FLNB | filamin B, beta | 0.0479824 |
| PODXL | podocalyxin-like | 0.0473263 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0470401 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0453254 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0445169 |
| LDHA | lactate dehydrogenase A | 0.043479 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0428358 |
| APP | amyloid beta (A4) precursor protein | 0.0425459 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0421938 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0419778 |
| EPHA4 | EPH receptor A4 | 0.041656 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0412791 |
| CMIP | c-Maf inducing protein | 0.0410862 |
| CCNL1 | cyclin L1 | 0.040721 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0393214 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0389608 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0386123 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.038089 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0373048 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0369142 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0369112 |
| EHBP1 | EH domain binding protein 1 | 0.0362777 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0360155 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0355705 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0355522 |
| RNF213 | ring finger protein 213 | 0.0355418 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0353431 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0353102 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0350799 |
| ACTG1 | actin gamma 1 | 0.0348595 |
| EGR1 | early growth response 1 | 0.0341783 |
| RAD51B | RAD51 paralog B | 0.0333309 |
| FNIP1 | folliculin interacting protein 1 | 0.0322322 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0321517 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0316145 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0314292 |
| DNER | delta/notch-like EGF repeat containing | 0.0312968 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0310191 |
| HMGA1 | high mobility group AT-hook 1 | 0.0308572 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0298017 |
| HDAC9 | histone deacetylase 9 | 0.0296495 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0291261 |
| TNS3 | tensin 3 | 0.028794 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0284277 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0277639 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0277558 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0273159 |
| NAV2 | neuron navigator 2 | 0.0272073 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0271351 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0270988 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0268827 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0265599 |
| RCOR1 | REST corepressor 1 | 0.0260573 |
| EFNA5 | ephrin-A5 | 0.0259728 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0258747 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0254307 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0253538 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0252711 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0251431 |
| EXOC4 | exocyst complex component 4 | 0.0245956 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0244341 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.024416 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0241301 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0241263 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0240658 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0237491 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0237059 |
| FBXO11 | F-box protein 11 | 0.0231894 |
| SPAG9 | sperm associated antigen 9 | 0.0226438 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0223512 |
| YEATS2 | YEATS domain containing 2 | 0.0222325 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0221139 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0219381 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0215274 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0214916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.241363 |
| TMSB10 | thymosin beta 10 | -0.159555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110209 |
| PTMA | prothymosin, alpha | -0.078797 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0780756 |
| TMSB4X | thymosin beta 4, X-linked | -0.0752337 |
| FTL | ferritin, light polypeptide | -0.0693454 |
| HLA-B | major histocompatibility complex, class I, B | -0.0485278 |
| RPS12 | ribosomal protein S12 | -0.0466789 |
| MT2A | metallothionein 2A | -0.0464291 |
| RPS8 | ribosomal protein S8 | -0.0463523 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0429738 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0414408 |
| SRGN | serglycin | -0.0413244 |
| RPS24 | ribosomal protein S24 | -0.0396843 |
| RPL31 | ribosomal protein L31 | -0.0370454 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0364574 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0319049 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0317338 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0314651 |
| EZR | ezrin | -0.0308283 |
| RPL26 | ribosomal protein L26 | -0.0302603 |
| RPL5 | ribosomal protein L5 | -0.0299685 |
| RPS3 | ribosomal protein S3 | -0.0284038 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0281151 |
| RPL37A | ribosomal protein L37a | -0.0276959 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0276506 |
| RPL12 | ribosomal protein L12 | -0.0260165 |
| YBX1 | Y box binding protein 1 | -0.0257926 |
| OGA | O-GlcNAcase | -0.0255282 |
| RPLP2 | ribosomal protein, large, P2 | -0.0254641 |
| RBM25 | RNA binding motif protein 25 | -0.0250626 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0246027 |
| TXNRD1 | thioredoxin reductase 1 | -0.0245846 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0236441 |
| EREG | epiregulin | -0.0228289 |
| RPS27A | ribosomal protein S27a | -0.0223622 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0219609 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0217595 |
| MATR3 | matrin 3 | -0.0214138 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0213181 |
| RPS17 | ribosomal protein S17 | -0.0212153 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.021075 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0206856 |
| RPL32 | ribosomal protein L32 | -0.0197757 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.019534 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0193454 |
| DEK | DEK proto-oncogene | -0.0193095 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0189972 |
| RPL36A | ribosomal protein L36a | -0.0186345 |
| RPL19 | ribosomal protein L19 | -0.0184701 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0183003 |
| NPR2 | natriuretic peptide receptor 2 | -0.0182397 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0180557 |
| CCDC47 | coiled-coil domain containing 47 | -0.017639 |
| SDC4 | syndecan 4 | -0.0174694 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0171748 |
| RPS5 | ribosomal protein S5 | -0.0170681 |
| S100A10 | S100 calcium binding protein A10 | -0.0170157 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0166365 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.016602 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0165641 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0164407 |
| RPL7A | ribosomal protein L7a | -0.0160261 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0158497 |
| TNPO1 | transportin 1 | -0.0156534 |
| RPL28 | ribosomal protein L28 | -0.0156435 |
| RPS19 | ribosomal protein S19 | -0.0154441 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.015264 |
| RPS23 | ribosomal protein S23 | -0.0150431 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0149344 |
| B2M | beta-2-microglobulin | -0.0148738 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0147576 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0142132 |
| RRBP1 | ribosome binding protein 1 | -0.0140371 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.0137216 |
| RPLP1 | ribosomal protein, large, P1 | -0.0137063 |
| FERMT1 | fermitin family member 1 | -0.0136814 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0136543 |
| RPS10 | ribosomal protein S10 | -0.0134936 |
| HMGB2 | high mobility group box 2 | -0.0134927 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0134016 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0134004 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0133394 |
| RPS15 | ribosomal protein S15 | -0.0132781 |
| RBM39 | RNA binding motif protein 39 | -0.0130901 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0130796 |
| RPL35A | ribosomal protein L35a | -0.0126374 |
| RECQL | RecQ helicase-like | -0.0126201 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0126025 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0125357 |
| RPS4X | ribosomal protein S4, X-linked | -0.0123459 |
| HMGB1 | high mobility group box 1 | -0.012218 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0121661 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0121647 |
| NOP58 | NOP58 ribonucleoprotein | -0.0121512 |
| TPM3 | tropomyosin 3 | -0.0121478 |
| EMP1 | epithelial membrane protein 1 | -0.0121461 |
| RPL10A | ribosomal protein L10a | -0.0121299 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0121212 |
