| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0951143 |
| FAM13A | family with sequence similarity 13, member A | 0.0652563 |
| SPAG9 | sperm associated antigen 9 | 0.0506545 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0498834 |
| CCNL1 | cyclin L1 | 0.0472763 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0451131 |
| TMEM165 | transmembrane protein 165 | 0.0443433 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0410598 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0392051 |
| ARRDC3 | arrestin domain containing 3 | 0.0385842 |
| NGLY1 | N-glycanase 1 | 0.0348264 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0340732 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0340246 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0338787 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0331474 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.032023 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0297079 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0279888 |
| ATP13A3 | ATPase type 13A3 | 0.0264495 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.02549 |
| HELZ | helicase with zinc finger | 0.0252319 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0249752 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0245335 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0245269 |
| SRP54 | signal recognition particle 54kDa | 0.0239805 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0234632 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0226672 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0219218 |
| NPTN | neuroplastin | 0.0213772 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0209706 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0208227 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0207636 |
| CES1 | carboxylesterase 1 | 0.0207284 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0207219 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0200856 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0198672 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0197488 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0195104 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0191969 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0189179 |
| C1D | C1D nuclear receptor corepressor | 0.0187672 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0185763 |
| SLMAP | sarcolemma associated protein | 0.0184704 |
| H1-0 | H1.0 linker histone | 0.0183166 |
| MKI67 | marker of proliferation Ki-67 | 0.0179643 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0179312 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0170946 |
| UVRAG | UV radiation resistance associated | 0.0169061 |
| WASF2 | WAS protein family, member 2 | 0.0167546 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.016656 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0164471 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0162905 |
| FNIP1 | folliculin interacting protein 1 | 0.0162228 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0161741 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0159471 |
| EGR1 | early growth response 1 | 0.0159332 |
| YEATS2 | YEATS domain containing 2 | 0.0158824 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0153003 |
| YTHDC1 | YTH domain containing 1 | 0.0151935 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0148538 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0146506 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0145427 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0145411 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0144207 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0144178 |
| ATXN2L | ataxin 2-like | 0.0142051 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0139248 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0138859 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0138284 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0137954 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0137478 |
| NUP58 | nucleoporin 58 | 0.0137466 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.013695 |
| OGA | O-GlcNAcase | 0.0135823 |
| PAPOLA | poly(A) polymerase alpha | 0.0134579 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0134369 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0133887 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0132863 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.0132742 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0132342 |
| ECT2 | epithelial cell transforming 2 | 0.013233 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0131607 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0131373 |
| RNF145 | ring finger protein 145 | 0.0131255 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.013063 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0130525 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0130377 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0129024 |
| NCKAP1 | NCK-associated protein 1 | 0.0129 |
| QKI | QKI, KH domain containing, RNA binding | 0.0128625 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0127918 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0127746 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0125568 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.012513 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0123885 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0123881 |
| EP300 | E1A binding protein p300 | 0.0123212 |
| PER1 | period circadian clock 1 | 0.0122576 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0121443 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0121339 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.186578 |
| TXNRD1 | thioredoxin reductase 1 | -0.179638 |
| ASPH | aspartate beta-hydroxylase | -0.137794 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0951367 |
| FTL | ferritin, light polypeptide | -0.0926834 |
| EGFR | epidermal growth factor receptor | -0.0872658 |
| MT2A | metallothionein 2A | -0.0867447 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0845212 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0805554 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0804322 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0775954 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0748667 |
| RPS3 | ribosomal protein S3 | -0.0693865 |
| PTMA | prothymosin, alpha | -0.0689242 |
| CST3 | cystatin C | -0.0679759 |
| S100A10 | S100 calcium binding protein A10 | -0.0660703 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.06346 |
| LAMC2 | laminin, gamma 2 | -0.0611518 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0610896 |
| ENO1 | enolase 1, (alpha) | -0.0576935 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0526954 |
| GRAMD1B | GRAM domain containing 1B | -0.0520396 |
| MYOF | myoferlin | -0.0511543 |
| RPL31 | ribosomal protein L31 | -0.0495609 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0495006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0494321 |
| KRT18 | keratin 18, type I | -0.0492511 |
| RPS24 | ribosomal protein S24 | -0.0490575 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0475161 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0463726 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0447455 |
| KRT7 | keratin 7, type II | -0.0444501 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0442882 |
| CCND1 | cyclin D1 | -0.0439124 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0438341 |
| RPL37A | ribosomal protein L37a | -0.0431605 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0424684 |
| AHNAK | AHNAK nucleoprotein | -0.0423693 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0421917 |
| RPS12 | ribosomal protein S12 | -0.0417834 |
| RPS8 | ribosomal protein S8 | -0.0414465 |
| LMO7 | LIM domain 7 | -0.0411989 |
| SCEL | sciellin | -0.040953 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391845 |
| STC1 | stanniocalcin 1 | -0.0391228 |
| ACTG1 | actin gamma 1 | -0.0391109 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0390443 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0388079 |
| RPL19 | ribosomal protein L19 | -0.0382042 |
| TPM4 | tropomyosin 4 | -0.0379918 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0379497 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0378682 |
| TES | testin LIM domain protein | -0.0375834 |
| RPS27A | ribosomal protein S27a | -0.0369259 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0366418 |
| AREG | amphiregulin | -0.0361347 |
| RPS17 | ribosomal protein S17 | -0.0351449 |
| CANX | calnexin | -0.033987 |
| IER3 | immediate early response 3 | -0.0339833 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0325286 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0324536 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0319296 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0318753 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0315756 |
| RPS25 | ribosomal protein S25 | -0.0312012 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0311305 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0308367 |
| LAMA4 | laminin, alpha 4 | -0.0305534 |
| SLTM | SAFB-like, transcription modulator | -0.0305276 |
| RPL12 | ribosomal protein L12 | -0.0303485 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0303139 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.030182 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0296362 |
| SMYD3 | SET and MYND domain containing 3 | -0.0291459 |
| LDHA | lactate dehydrogenase A | -0.0291417 |
| KRT8 | keratin 8, type II | -0.029108 |
| GOLGB1 | golgin B1 | -0.029094 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0290309 |
| RPL11 | ribosomal protein L11 | -0.0285943 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0282546 |
| CDCP1 | CUB domain containing protein 1 | -0.0281979 |
| CUX1 | cut-like homeobox 1 | -0.02787 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0276858 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0276258 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0275797 |
| RPS23 | ribosomal protein S23 | -0.0274244 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0270589 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0269421 |
| RPL5 | ribosomal protein L5 | -0.0267397 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0262329 |
| EHBP1 | EH domain binding protein 1 | -0.0260862 |
| RPS6 | ribosomal protein S6 | -0.0260112 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0259317 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0258235 |
| RPL35A | ribosomal protein L35a | -0.025767 |
| RAB10 | RAB10, member RAS oncogene family | -0.0256887 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.025634 |
| PRDX1 | peroxiredoxin 1 | -0.025072 |
| ANXA2 | annexin A2 | -0.0250606 |
| FOXP1 | forkhead box P1 | -0.0248743 |
