| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.128477 |
| GOLGA4 | golgin A4 | 0.113038 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.104236 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.090228 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0869042 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0789204 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0715413 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0677513 |
| NAV2 | neuron navigator 2 | 0.065927 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0593621 |
| FAM13A | family with sequence similarity 13, member A | 0.0588624 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0582845 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0579868 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0575547 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0545829 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0542959 |
| NBAS | neuroblastoma amplified sequence | 0.0519318 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.051871 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0514651 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0512101 |
| USP34 | ubiquitin specific peptidase 34 | 0.0506307 |
| ANKRD28 | ankyrin repeat domain 28 | 0.05022 |
| SIK3 | SIK family kinase 3 | 0.0501917 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0486107 |
| PCBP2 | poly(rC) binding protein 2 | 0.0451839 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0451341 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0447341 |
| COG5 | component of oligomeric golgi complex 5 | 0.0444909 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0441853 |
| HELZ | helicase with zinc finger | 0.0435727 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0434695 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0433476 |
| MORF4L2 | mortality factor 4 like 2 | 0.0424577 |
| SPAG9 | sperm associated antigen 9 | 0.0424246 |
| SRP54 | signal recognition particle 54kDa | 0.0423657 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0412029 |
| FNIP1 | folliculin interacting protein 1 | 0.0407614 |
| LOX | lysyl oxidase | 0.0404586 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0401083 |
| RBM39 | RNA binding motif protein 39 | 0.0399062 |
| SEC24A | SEC24 family member A | 0.0398841 |
| COPA | coatomer protein complex, subunit alpha | 0.0397223 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0392619 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0387228 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0385891 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0385291 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0382947 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0381804 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0380756 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0379456 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0373115 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0372639 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0365106 |
| MEF2A | myocyte enhancer factor 2A | 0.0344949 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0344753 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0339748 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0331404 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0327242 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.032617 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0320555 |
| NGLY1 | N-glycanase 1 | 0.0319309 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.031847 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0317867 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0316932 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0314572 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0314041 |
| FAM107B | family with sequence similarity 107, member B | 0.031221 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0311661 |
| TNNC1 | troponin C type 1 (slow) | 0.0311019 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0310169 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0307208 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0305222 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0300544 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0300113 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0299736 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0299566 |
| MYOF | myoferlin | 0.0298204 |
| EGFR | epidermal growth factor receptor | 0.0297762 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.029692 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0294523 |
| RAB7A | RAB7A, member RAS oncogene family | 0.029003 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0287327 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.028706 |
| MCL1 | myeloid cell leukemia 1 | 0.0283484 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0280728 |
| CD109 | CD109 molecule | 0.0278865 |
| HDAC9 | histone deacetylase 9 | 0.0278337 |
| PRELID2 | PRELI domain containing 2 | 0.0276332 |
| ATP13A3 | ATPase type 13A3 | 0.0275215 |
| LRRC49 | leucine rich repeat containing 49 | 0.0270334 |
| CALU | calumenin | 0.0268608 |
| SETD5 | SET domain containing 5 | 0.0265576 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.026181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0259067 |
| SCFD1 | sec1 family domain containing 1 | 0.0258056 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0257111 |
| HM13 | histocompatibility (minor) 13 | 0.025681 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0256628 |
| VEGFA | vascular endothelial growth factor A | 0.0255714 |
| GPC6 | glypican 6 | 0.0255556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.165547 |
| VIM | vimentin | -0.156349 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.114746 |
| FTL | ferritin, light polypeptide | -0.100998 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0929488 |
| NRG1 | neuregulin 1 | -0.0919762 |
| MT2A | metallothionein 2A | -0.0847628 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0779201 |
| GLCCI1 | glucocorticoid induced 1 | -0.0766984 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0743619 |
| STC1 | stanniocalcin 1 | -0.073803 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0703067 |
| HMGA2 | high mobility group AT-hook 2 | -0.0702368 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0688784 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0589487 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0587309 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0577605 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0574351 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0538216 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0522367 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0516809 |
| AHNAK | AHNAK nucleoprotein | -0.0506608 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0500421 |
| FAM20C | family with sequence similarity 20, member C | -0.0495046 |
| PTMA | prothymosin, alpha | -0.0489686 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0464968 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0459989 |
| IER3 | immediate early response 3 | -0.045752 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0448133 |
| TMSB4X | thymosin beta 4, X-linked | -0.0445398 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0441033 |
| MTSS1 | metastasis suppressor 1 | -0.0435293 |
| ENOSF1 | enolase superfamily member 1 | -0.0431569 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0424035 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0419911 |
| CDH13 | cadherin 13 | -0.0417696 |
| RPS19 | ribosomal protein S19 | -0.0411345 |
| RAI14 | retinoic acid induced 14 | -0.0407037 |
| RPLP2 | ribosomal protein, large, P2 | -0.0395443 |
| CDCP1 | CUB domain containing protein 1 | -0.038662 |
| NRP1 | neuropilin 1 | -0.0383753 |
| EREG | epiregulin | -0.037619 |
| HLA-B | major histocompatibility complex, class I, B | -0.0375288 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0373557 |
| RPLP1 | ribosomal protein, large, P1 | -0.0372562 |
| RPL32 | ribosomal protein L32 | -0.037227 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0370805 |
| RPS24 | ribosomal protein S24 | -0.0364893 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0363566 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0363535 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0360106 |
| B2M | beta-2-microglobulin | -0.0354346 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0348915 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0348853 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0343446 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0342618 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0339343 |
| IL1B | interleukin 1, beta | -0.0334778 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0334035 |
| RPL31 | ribosomal protein L31 | -0.0333095 |
| ETV6 | ets variant 6 | -0.0329359 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0320478 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0319577 |
| FN1 | fibronectin 1 | -0.0315276 |
| SLFN5 | schlafen family member 5 | -0.0309031 |
| ANXA10 | annexin A10 | -0.0306444 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0297335 |
| TPM4 | tropomyosin 4 | -0.0295549 |
| RIGI | RNA sensor RIG-I | -0.0294776 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0294153 |
| S100A10 | S100 calcium binding protein A10 | -0.0292516 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0290068 |
| CP | ceruloplasmin (ferroxidase) | -0.0289788 |
| RPL35A | ribosomal protein L35a | -0.0287905 |
| DIAPH2 | diaphanous-related formin 2 | -0.0285831 |
| SP100 | SP100 nuclear antigen | -0.0283535 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0281199 |
| MECOM | MDS1 and EVI1 complex locus | -0.0280222 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0278484 |
| EFNA5 | ephrin-A5 | -0.0272436 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0272132 |
| CLMP | CXADR-like membrane protein | -0.0269081 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.026882 |
| RPL37A | ribosomal protein L37a | -0.0267735 |
| RPS29 | ribosomal protein S29 | -0.026648 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0265953 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0260145 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.025964 |
| NUMB | numb homolog (Drosophila) | -0.0259054 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.025734 |
| EHBP1 | EH domain binding protein 1 | -0.0253911 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0253169 |
| S100A6 | S100 calcium binding protein A6 | -0.0252004 |
| RPS12 | ribosomal protein S12 | -0.025129 |
| RPS8 | ribosomal protein S8 | -0.0250278 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0247689 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0247056 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0246275 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | -0.0242307 |
| VRK2 | vaccinia related kinase 2 | -0.0237309 |
