| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.154028 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.137173 |
| PM20D1 | peptidase M20 domain containing 1 | 0.11321 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0896179 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0894393 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0799163 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.068543 |
| WWOX | WW domain containing oxidoreductase | 0.0620855 |
| EGR1 | early growth response 1 | 0.0574719 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0511364 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0506664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0465105 |
| PDLIM5 | PDZ and LIM domain 5 | 0.044566 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0426409 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0405282 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0391881 |
| CMIP | c-Maf inducing protein | 0.0384555 |
| USP34 | ubiquitin specific peptidase 34 | 0.0380047 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0370304 |
| OSMR | oncostatin M receptor | 0.0360776 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0354386 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0351653 |
| RTN4 | reticulon 4 | 0.0349984 |
| RPS19 | ribosomal protein S19 | 0.033587 |
| CCNL1 | cyclin L1 | 0.0331842 |
| RPLP1 | ribosomal protein, large, P1 | 0.0331584 |
| BICC1 | BicC family RNA binding protein 1 | 0.0330328 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0326721 |
| RAD51B | RAD51 paralog B | 0.0325808 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0324462 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0320558 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.031917 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0311675 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0303912 |
| NRG1 | neuregulin 1 | 0.0303213 |
| PCNX1 | pecanex 1 | 0.029691 |
| RRM2 | ribonucleotide reductase M2 | 0.0293898 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0291399 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0287484 |
| AREG | amphiregulin | 0.0285246 |
| PHIP | pleckstrin homology domain interacting protein | 0.0282741 |
| NEBL | nebulette | 0.0280862 |
| TXNRD1 | thioredoxin reductase 1 | 0.0278376 |
| MKI67 | marker of proliferation Ki-67 | 0.0277629 |
| NUP58 | nucleoporin 58 | 0.0277312 |
| RCOR1 | REST corepressor 1 | 0.0268891 |
| RPL13A | ribosomal protein L13a | 0.0265963 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0261469 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0257342 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.02559 |
| RPS23 | ribosomal protein S23 | 0.0253019 |
| COG5 | component of oligomeric golgi complex 5 | 0.0252012 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0250788 |
| RPL31 | ribosomal protein L31 | 0.0249971 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0247386 |
| ANKRD28 | ankyrin repeat domain 28 | 0.024694 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0246459 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0238325 |
| ZNF277 | zinc finger protein 277 | 0.0236244 |
| KLF6 | Kruppel-like factor 6 | 0.0235375 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0234099 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0230619 |
| ITGB5 | integrin, beta 5 | 0.0229819 |
| CLTC | clathrin, heavy chain (Hc) | 0.0227789 |
| BMP6 | bone morphogenetic protein 6 | 0.0226895 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0223654 |
| NHSL1 | NHS-like 1 | 0.0222947 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0221921 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0220252 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0217904 |
| EPGN | epithelial mitogen | 0.0216707 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0213293 |
| NBAS | neuroblastoma amplified sequence | 0.0211606 |
| GLIS3 | GLIS family zinc finger 3 | 0.0208891 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0207842 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0207179 |
| RPL9 | ribosomal protein L9 | 0.0203932 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0203878 |
| RPS12 | ribosomal protein S12 | 0.0202677 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0202594 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0202248 |
| CABIN1 | calcineurin binding protein 1 | 0.0201324 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0201216 |
| SP3 | Sp3 transcription factor | 0.0201207 |
| ATXN3 | ataxin 3 | 0.0200009 |
| VMP1 | vacuole membrane protein 1 | 0.0199844 |
| BRD2 | bromodomain containing 2 | 0.0199392 |
| RPS29 | ribosomal protein S29 | 0.0197134 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0197093 |
| GANAB | glucosidase, alpha; neutral AB | 0.0196794 |
| SON | SON DNA binding protein | 0.0196438 |
| WDR43 | WD repeat domain 43 | 0.0194612 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0193848 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0193522 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0193065 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0192981 |
| SCFD1 | sec1 family domain containing 1 | 0.0188889 |
| RPL36 | ribosomal protein L36 | 0.0186961 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.01865 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0186039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.172743 |
| FTL | ferritin, light polypeptide | -0.172342 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149388 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.139038 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0958022 |
| VIM | vimentin | -0.0812522 |
| TMSB10 | thymosin beta 10 | -0.0747277 |
| S100A6 | S100 calcium binding protein A6 | -0.0738843 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0685949 |
| IGF2 | insulin-like growth factor 2 | -0.0635513 |
| S100A10 | S100 calcium binding protein A10 | -0.0588467 |
| IER3 | immediate early response 3 | -0.0574176 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0539566 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0503389 |
| FGB | fibrinogen beta chain | -0.0498095 |
| CAVIN1 | caveolae associated protein 1 | -0.0475459 |
| ACTG1 | actin gamma 1 | -0.0460115 |
| HLA-B | major histocompatibility complex, class I, B | -0.0444624 |
| ANXA2 | annexin A2 | -0.0440997 |
| GNAS | GNAS complex locus | -0.04185 |
| SRGN | serglycin | -0.0416273 |
| PTMA | prothymosin, alpha | -0.0415378 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0414115 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0407146 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0399688 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0390376 |
| DENND4A | DENN/MADD domain containing 4A | -0.0389498 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0382306 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0380075 |
| FAM168A | family with sequence similarity 168, member A | -0.0370681 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0370186 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0359971 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0354287 |
| YBX1 | Y box binding protein 1 | -0.0331882 |
| FMNL2 | formin-like 2 | -0.0330015 |
| AHNAK | AHNAK nucleoprotein | -0.0319536 |
| ASPH | aspartate beta-hydroxylase | -0.0317087 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0316338 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0313389 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.030576 |
| CLU | clusterin | -0.0300634 |
| LDHA | lactate dehydrogenase A | -0.0293805 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0291469 |
| B2M | beta-2-microglobulin | -0.0291429 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0288399 |
| ASTN2 | astrotactin 2 | -0.0287959 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0284156 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0283593 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0281992 |
| APP | amyloid beta (A4) precursor protein | -0.027827 |
| PTK2 | protein tyrosine kinase 2 | -0.0278026 |
| LMNA | lamin A/C | -0.0277511 |
| POTEF | POTE ankyrin domain family, member F | -0.0275554 |
| ENO1 | enolase 1, (alpha) | -0.0275196 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0272688 |
| UBC | ubiquitin C | -0.0270611 |
| TAGLN2 | transgelin 2 | -0.0266104 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0264227 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0263174 |
| MPZL1 | myelin protein zero-like 1 | -0.0261709 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0261155 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0250684 |
| SETD5 | SET domain containing 5 | -0.024969 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0249321 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0246798 |
| CALR | calreticulin | -0.023817 |
| SEPTIN7 | septin 7 | -0.0237781 |
| SDC4 | syndecan 4 | -0.0233756 |
| TPM1 | tropomyosin 1 (alpha) | -0.0233292 |
| S100A9 | S100 calcium binding protein A9 | -0.0230587 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0229822 |
| TPM3 | tropomyosin 3 | -0.0228681 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0228035 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0222097 |
| CD99 | CD99 molecule | -0.0221323 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0221166 |
| JUN | jun proto-oncogene | -0.0218938 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0218299 |
| FERMT2 | fermitin family member 2 | -0.0217791 |
| HLA-A | major histocompatibility complex, class I, A | -0.0217235 |
| ANXA1 | annexin A1 | -0.0213519 |
| TNS3 | tensin 3 | -0.0212756 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0209979 |
| CANX | calnexin | -0.0208495 |
| DENND5B | DENN/MADD domain containing 5B | -0.0207156 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.020484 |
| CUX1 | cut-like homeobox 1 | -0.0202713 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0202227 |
| TPI1 | triosephosphate isomerase 1 | -0.0199455 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.019856 |
| TFG | TRK-fused gene | -0.0197964 |
| NDRG1 | N-myc downstream regulated 1 | -0.0197685 |
| MAP4 | microtubule-associated protein 4 | -0.0197361 |
| ADM | adrenomedullin | -0.0195793 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0195542 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0195196 |
| SYNRG | synergin, gamma | -0.0194462 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0193296 |
| FNBP1L | formin binding protein 1-like | -0.0192059 |
| RPLP0 | ribosomal protein, large, P0 | -0.0191637 |
