| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.191259 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.186465 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.125064 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0817977 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0784807 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0698881 |
| CCNL1 | cyclin L1 | 0.0690466 |
| ACTG1 | actin gamma 1 | 0.0660995 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0613447 |
| LDHA | lactate dehydrogenase A | 0.0542924 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0477049 |
| PGK1 | phosphoglycerate kinase 1 | 0.0472696 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0468397 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0411636 |
| PKM | pyruvate kinase, muscle | 0.0376452 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0366521 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0354818 |
| RPL35A | ribosomal protein L35a | 0.0349297 |
| CTSB | cathepsin B | 0.0336228 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0332913 |
| FAM13A | family with sequence similarity 13, member A | 0.0321793 |
| FLNA | filamin A, alpha | 0.0317592 |
| MXD1 | MAX dimerization protein 1 | 0.0313749 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0312595 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0311416 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0309124 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.029386 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0292909 |
| RPL23 | ribosomal protein L23 | 0.0291195 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0285366 |
| OCLN | occludin | 0.0273932 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.026778 |
| GNAS | GNAS complex locus | 0.0267577 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0265722 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0255616 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0251566 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0248828 |
| S100A6 | S100 calcium binding protein A6 | 0.0248755 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0248428 |
| COPA | coatomer protein complex, subunit alpha | 0.0246565 |
| HMGA1 | high mobility group AT-hook 1 | 0.0244099 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0239863 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.023519 |
| FBXO34 | F-box protein 34 | 0.0234513 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0234389 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0230826 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0215988 |
| ARF1 | ADP-ribosylation factor 1 | 0.0214306 |
| WASF2 | WAS protein family, member 2 | 0.0214139 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0211336 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0211302 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0207188 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0207115 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0203996 |
| KRT7 | keratin 7, type II | 0.0201095 |
| AOPEP | aminopeptidase O (putative) | 0.0193122 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0192663 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0192352 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0191255 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0189396 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0187135 |
| RPN1 | ribophorin I | 0.0186451 |
| GANAB | glucosidase, alpha; neutral AB | 0.0181378 |
| MSI2 | musashi RNA-binding protein 2 | 0.0176852 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0176323 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0172143 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0170569 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.016992 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0168314 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0167064 |
| TPI1 | triosephosphate isomerase 1 | 0.0167054 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0166278 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0164272 |
| SIK3 | SIK family kinase 3 | 0.0164018 |
| PLAU | plasminogen activator, urokinase | 0.0163558 |
| ANXA2 | annexin A2 | 0.0162852 |
| TUBB | tubulin, beta class I | 0.0162544 |
| FLNB | filamin B, beta | 0.0160772 |
| FLNC | filamin C, gamma | 0.0159785 |
| MEF2D | myocyte enhancer factor 2D | 0.0158785 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0158123 |
| CD109 | CD109 molecule | 0.0157676 |
| POTEF | POTE ankyrin domain family, member F | 0.0156153 |
| HELZ | helicase with zinc finger | 0.0155959 |
| SEC24D | SEC24 family member D | 0.0155257 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0153782 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0151383 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.015085 |
| HLA-A | major histocompatibility complex, class I, A | 0.0150626 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0146181 |
| AGRN | agrin | 0.0145639 |
| JUP | junction plakoglobin | 0.0144083 |
| PCBP1 | poly(rC) binding protein 1 | 0.0142746 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0141409 |
| PLS3 | plastin 3 | 0.0141216 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0139728 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0138776 |
| WTAP | Wilms tumor 1 associated protein | 0.0138454 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0137022 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0135462 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.234828 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.168168 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.14863 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.140106 |
| FTL | ferritin, light polypeptide | -0.127472 |
| NDRG1 | N-myc downstream regulated 1 | -0.109962 |
| ASPH | aspartate beta-hydroxylase | -0.109793 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0995117 |
| PTMA | prothymosin, alpha | -0.0941356 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0904345 |
| LAMC2 | laminin, gamma 2 | -0.0822644 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0734534 |
| TMSB10 | thymosin beta 10 | -0.0731036 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.072367 |
| TMSB4X | thymosin beta 4, X-linked | -0.0682179 |
| DTNA | dystrobrevin, alpha | -0.0662615 |
| TXNRD1 | thioredoxin reductase 1 | -0.0628653 |
| DSPP | dentin sialophosphoprotein | -0.0586003 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0560803 |
| TPM3 | tropomyosin 3 | -0.0558678 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0539006 |
| CANX | calnexin | -0.0522772 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0500847 |
| RPS3 | ribosomal protein S3 | -0.0499807 |
| AHNAK | AHNAK nucleoprotein | -0.0495033 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0492906 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0477626 |
| UPP1 | uridine phosphorylase 1 | -0.0464949 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0461726 |
| RPS12 | ribosomal protein S12 | -0.0442764 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0430377 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0422097 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0420507 |
| GOLGA4 | golgin A4 | -0.0418399 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0417181 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0403093 |
| EPCAM | epithelial cell adhesion molecule | -0.0401654 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0392825 |
| S100A10 | S100 calcium binding protein A10 | -0.0389091 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0383471 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0381201 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0379262 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0368674 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0367041 |
| RPS6 | ribosomal protein S6 | -0.0366042 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354703 |
| SET | SET nuclear proto-oncogene | -0.0353619 |
| HSPA8 | heat shock 70kDa protein 8 | -0.035242 |
| EZR | ezrin | -0.035079 |
| MSN | moesin | -0.0350327 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0348441 |
| RPL32 | ribosomal protein L32 | -0.034821 |
| MYO6 | myosin VI | -0.0347672 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0345949 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0345213 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0343651 |
| DSG2 | desmoglein 2 | -0.0339457 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0338805 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0333419 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.032998 |
| RPS17 | ribosomal protein S17 | -0.032667 |
| RPL5 | ribosomal protein L5 | -0.032614 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0318299 |
| SQSTM1 | sequestosome 1 | -0.0306962 |
| TPM4 | tropomyosin 4 | -0.0306407 |
| MKI67 | marker of proliferation Ki-67 | -0.0304865 |
| DST | dystonin | -0.0300737 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.030001 |
| RPS8 | ribosomal protein S8 | -0.0295598 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0292665 |
| MEF2A | myocyte enhancer factor 2A | -0.0286877 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0286562 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0284048 |
| CENPF | centromere protein F, 350/400kDa | -0.0283251 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0281898 |
| BBX | bobby sox homolog (Drosophila) | -0.0280459 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.0280377 |
| RPL14 | ribosomal protein L14 | -0.0278608 |
| NAV2 | neuron navigator 2 | -0.0276304 |
| SDC4 | syndecan 4 | -0.0275835 |
| RPLP2 | ribosomal protein, large, P2 | -0.0273417 |
| DSTN | destrin (actin depolymerizing factor) | -0.0272166 |
| RPL31 | ribosomal protein L31 | -0.0270442 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0267753 |
| RPL3 | ribosomal protein L3 | -0.0266335 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0262944 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0260242 |
| SEPTIN7 | septin 7 | -0.0260089 |
| RPS2 | ribosomal protein S2 | -0.0257943 |
| ANO6 | anoctamin 6 | -0.0256206 |
| ANXA1 | annexin A1 | -0.0255766 |
| FHIT | fragile histidine triad | -0.0254622 |
| RPS27A | ribosomal protein S27a | -0.0252497 |
| JMJD1C | jumonji domain containing 1C | -0.0252424 |
| RPL7 | ribosomal protein L7 | -0.0251357 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0249472 |
| MYO5B | myosin VB | -0.0247706 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0244092 |
| MAP4 | microtubule-associated protein 4 | -0.0243965 |
| RPL19 | ribosomal protein L19 | -0.024135 |
