| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | 0.165898 |
| PDGFC | platelet derived growth factor C | 0.0832701 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0826538 |
| EVI5 | ecotropic viral integration site 5 | 0.0765914 |
| HDAC9 | histone deacetylase 9 | 0.0718769 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0682792 |
| GOLGA4 | golgin A4 | 0.0663083 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0619621 |
| TJP1 | tight junction protein 1 | 0.0613296 |
| POTEF | POTE ankyrin domain family, member F | 0.0567238 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0559296 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0557462 |
| LDHA | lactate dehydrogenase A | 0.0541891 |
| SLC38A2 | solute carrier family 38, member 2 | 0.053365 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0510626 |
| EGFR | epidermal growth factor receptor | 0.0506971 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0455454 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0442727 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0437827 |
| FLNB | filamin B, beta | 0.0426142 |
| ANK2 | ankyrin 2, neuronal | 0.0420231 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0413438 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0407691 |
| RTN4 | reticulon 4 | 0.0406064 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0404728 |
| YAP1 | Yes-associated protein 1 | 0.0399998 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0396328 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0394872 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0380547 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0380254 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0379366 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.037423 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0370561 |
| FOXP1 | forkhead box P1 | 0.0368485 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0365377 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0365222 |
| QKI | QKI, KH domain containing, RNA binding | 0.0364888 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0362604 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0355358 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0352704 |
| TCF12 | transcription factor 12 | 0.0350493 |
| JMJD1C | jumonji domain containing 1C | 0.0346395 |
| DUSP4 | dual specificity phosphatase 4 | 0.033751 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0336975 |
| CDC73 | cell division cycle 73 | 0.0335699 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0333748 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0331791 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0328655 |
| PCBP2 | poly(rC) binding protein 2 | 0.0318321 |
| NBAS | neuroblastoma amplified sequence | 0.0312077 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0304945 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0303542 |
| RPS2 | ribosomal protein S2 | 0.0302968 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0301812 |
| USP34 | ubiquitin specific peptidase 34 | 0.0299942 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0296822 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0295489 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0292495 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0290294 |
| SQSTM1 | sequestosome 1 | 0.0283183 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0282318 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0280441 |
| ZNF207 | zinc finger protein 207 | 0.0279173 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0278368 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0266997 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0265819 |
| CALU | calumenin | 0.0262276 |
| NCKAP1 | NCK-associated protein 1 | 0.0259589 |
| RHOA | ras homolog family member A | 0.0258861 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0253978 |
| CCNL1 | cyclin L1 | 0.0251296 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0251194 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0250751 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.024988 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0249355 |
| MLIP | muscular LMNA-interacting protein | 0.0246687 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0244668 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0243217 |
| EZR | ezrin | 0.0243197 |
| COG6 | component of oligomeric golgi complex 6 | 0.0241829 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0241289 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0241064 |
| SGMS1 | sphingomyelin synthase 1 | 0.0240732 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0239826 |
| NUP58 | nucleoporin 58 | 0.0238333 |
| FNIP1 | folliculin interacting protein 1 | 0.023789 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0236915 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.023602 |
| SESN2 | sestrin 2 | 0.0235744 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0235318 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.023401 |
| TNPO1 | transportin 1 | 0.023359 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0230721 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0229816 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0229158 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0228778 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0228305 |
| METTL15 | methyltransferase like 15 | 0.0228186 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0227741 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.022755 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.162636 |
| AHNAK | AHNAK nucleoprotein | -0.153596 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0876106 |
| BMP10 | bone morphogenetic protein 10 | -0.0809766 |
| TMSB4X | thymosin beta 4, X-linked | -0.0777595 |
| MKI67 | marker of proliferation Ki-67 | -0.0697559 |
| MT2A | metallothionein 2A | -0.0574422 |
| DIAPH3 | diaphanous-related formin 3 | -0.0559479 |
| GLI3 | GLI family zinc finger 3 | -0.0553074 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0497611 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0481366 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0477123 |
| RPS8 | ribosomal protein S8 | -0.0454493 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0453155 |
| RPL34 | ribosomal protein L34 | -0.0441871 |
| NAV2 | neuron navigator 2 | -0.0437211 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0435098 |
| RPS27A | ribosomal protein S27a | -0.042788 |
| RPL7A | ribosomal protein L7a | -0.0386189 |
| RPL23 | ribosomal protein L23 | -0.0370577 |
| S100A6 | S100 calcium binding protein A6 | -0.0370178 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.036806 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0367473 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0360482 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0359365 |
| IGF2 | insulin-like growth factor 2 | -0.0342469 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0342365 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0324999 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0314845 |
| RPS6 | ribosomal protein S6 | -0.0304188 |
| GLI2 | GLI family zinc finger 2 | -0.0301366 |
| B2M | beta-2-microglobulin | -0.0297927 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0295088 |
| RPS24 | ribosomal protein S24 | -0.0294045 |
| CENPE | centromere protein E, 312kDa | -0.0293752 |
| RPS21 | ribosomal protein S21 | -0.0281677 |
| HMGB2 | high mobility group box 2 | -0.0270225 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0270146 |
| ZNF438 | zinc finger protein 438 | -0.0267684 |
| RPL36 | ribosomal protein L36 | -0.0265974 |
| RRBP1 | ribosome binding protein 1 | -0.0261883 |
| HJURP | Holliday junction recognition protein | -0.0260061 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0258305 |
| TPM4 | tropomyosin 4 | -0.025252 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0251733 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0251308 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0249238 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0245045 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0240327 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0238337 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0236333 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.023528 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.023454 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0232852 |
| BCOR | BCL6 corepressor | -0.0224648 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0223248 |
| KPNB1 | karyopherin (importin) beta 1 | -0.022149 |
| RPS25 | ribosomal protein S25 | -0.0219485 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.021846 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0216053 |
| KIF5B | kinesin family member 5B | -0.0214997 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0213823 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0213454 |
| CTBP2 | C-terminal binding protein 2 | -0.02132 |
| CENPF | centromere protein F, 350/400kDa | -0.0212661 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.021016 |
| NRF1 | nuclear respiratory factor 1 | -0.021006 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0210041 |
| ANLN | anillin, actin binding protein | -0.0208036 |
| CEP112 | centrosomal protein 112kDa | -0.020743 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0205213 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0205008 |
| ACTG1 | actin gamma 1 | -0.0200799 |
| RPLP0 | ribosomal protein, large, P0 | -0.0199738 |
| RSF1 | remodeling and spacing factor 1 | -0.0199631 |
| YY1 | YY1 transcription factor | -0.0194957 |
| RPS19 | ribosomal protein S19 | -0.0193927 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0193678 |
| CCDC88A | coiled-coil domain containing 88A | -0.0193053 |
| S100A10 | S100 calcium binding protein A10 | -0.01916 |
| KIF18B | kinesin family member 18B | -0.0190482 |
| SEC61G | Sec61 gamma subunit | -0.0190371 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0189465 |
| MAP4 | microtubule-associated protein 4 | -0.0188799 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0187829 |
| DST | dystonin | -0.0186959 |
| RPL8 | ribosomal protein L8 | -0.0186373 |
| RRM2 | ribonucleotide reductase M2 | -0.0185783 |
| MYO5C | myosin VC | -0.0184869 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0184757 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.0182836 |
| RPL31 | ribosomal protein L31 | -0.0181692 |
| DIAPH2 | diaphanous-related formin 2 | -0.0181514 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0181056 |
| FMN1 | formin 1 | -0.0179145 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0178327 |
| RPS27 | ribosomal protein S27 | -0.0178253 |
| GPATCH8 | G patch domain containing 8 | -0.0177177 |
| CUL1 | cullin 1 | -0.0176349 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0176246 |
