| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.142592 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.12337 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.100082 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0951835 |
| PGK1 | phosphoglycerate kinase 1 | 0.0947397 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0801557 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0783111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0733619 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0672937 |
| LDHA | lactate dehydrogenase A | 0.064001 |
| CD44 | CD44 molecule (Indian blood group) | 0.0608803 |
| PDE10A | phosphodiesterase 10A | 0.0597439 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0559501 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0554275 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0519547 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0474614 |
| FLNA | filamin A, alpha | 0.0472886 |
| GLIS3 | GLIS family zinc finger 3 | 0.0470474 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0467228 |
| STC1 | stanniocalcin 1 | 0.0450774 |
| SFTPA2 | surfactant protein A2 | 0.0449866 |
| SMAD3 | SMAD family member 3 | 0.0431821 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0428074 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0424986 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0420789 |
| HDAC9 | histone deacetylase 9 | 0.0418888 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.039334 |
| KYNU | kynureninase | 0.0392508 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0386291 |
| LOXL2 | lysyl oxidase-like 2 | 0.0370769 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.037075 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0360126 |
| LOX | lysyl oxidase | 0.035008 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0342166 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.033707 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0334062 |
| RND3 | Rho family GTPase 3 | 0.0333311 |
| FLNB | filamin B, beta | 0.0330281 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0316789 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0315005 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.030399 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0302138 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0298391 |
| THBS2 | thrombospondin 2 | 0.0293413 |
| FNIP1 | folliculin interacting protein 1 | 0.0292898 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0292531 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0291551 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0286223 |
| TNS3 | tensin 3 | 0.0282297 |
| ATXN1 | ataxin 1 | 0.0281691 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0276963 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0275979 |
| EGFR | epidermal growth factor receptor | 0.0271094 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0267831 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0265342 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0262374 |
| CD68 | CD68 molecule | 0.0260457 |
| C3 | complement component 3 | 0.0257514 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0252901 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0251804 |
| INHBA | inhibin, beta A | 0.0249 |
| OSMR | oncostatin M receptor | 0.0244651 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0244331 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0241199 |
| TGM2 | transglutaminase 2 | 0.0239333 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0237594 |
| NABP1 | nucleic acid binding protein 1 | 0.0236743 |
| VCL | vinculin | 0.023278 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0230389 |
| ACTN1 | actinin, alpha 1 | 0.0227649 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0227173 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0225752 |
| COL5A1 | collagen, type V, alpha 1 | 0.0223866 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0223732 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0220082 |
| CLTC | clathrin, heavy chain (Hc) | 0.0219397 |
| ARFGEF3 | ARFGEF family member 3 | 0.0217179 |
| NAV2 | neuron navigator 2 | 0.0214627 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0203632 |
| MMP2 | matrix metallopeptidase 2 | 0.0203564 |
| GANAB | glucosidase, alpha; neutral AB | 0.0200974 |
| NONO | non-POU domain containing, octamer-binding | 0.0198448 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0198061 |
| CTSB | cathepsin B | 0.0197438 |
| VEGFA | vascular endothelial growth factor A | 0.0196255 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0195382 |
| RUNX1 | runt-related transcription factor 1 | 0.0193673 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0190056 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.018767 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0186032 |
| GPC6 | glypican 6 | 0.0185921 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0185505 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0185115 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0185055 |
| HMGA2 | high mobility group AT-hook 2 | 0.0184754 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0180537 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0179269 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0178423 |
| FOXO3 | forkhead box O3 | 0.0178024 |
| FAM20C | family with sequence similarity 20, member C | 0.0177688 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.198708 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.140769 |
| FTL | ferritin, light polypeptide | -0.125065 |
| TMSB10 | thymosin beta 10 | -0.095342 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0794023 |
| PTMA | prothymosin, alpha | -0.0602064 |
| IER3 | immediate early response 3 | -0.0591559 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0571397 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0555757 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0532627 |
| RPS12 | ribosomal protein S12 | -0.0528349 |
| RPS24 | ribosomal protein S24 | -0.0498606 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.048945 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0462323 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0410833 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0400594 |
| RPS6 | ribosomal protein S6 | -0.0395411 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0386377 |
| ZNF292 | zinc finger protein 292 | -0.0378527 |
| YBX1 | Y box binding protein 1 | -0.0374061 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.037331 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0372794 |
| QKI | QKI, KH domain containing, RNA binding | -0.0366817 |
| RPS3 | ribosomal protein S3 | -0.0353007 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0334551 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0323076 |
| TXNRD1 | thioredoxin reductase 1 | -0.0309446 |
| CANX | calnexin | -0.0304986 |
| TAPBP | TAP binding protein (tapasin) | -0.0299279 |
| PCBP2 | poly(rC) binding protein 2 | -0.0283283 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.027921 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0278643 |
| FRMD4A | FERM domain containing 4A | -0.0275078 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0271069 |
| MATR3 | matrin 3 | -0.0269632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0263456 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0261786 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0260159 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0259639 |
| DSTN | destrin (actin depolymerizing factor) | -0.0255205 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.025511 |
| OGA | O-GlcNAcase | -0.0254252 |
| TPM4 | tropomyosin 4 | -0.0253027 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0246488 |
| ARF4 | ADP-ribosylation factor 4 | -0.0245676 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0244693 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0239262 |
| RPL31 | ribosomal protein L31 | -0.0238251 |
| WDR45B | WD repeat domain 45B | -0.0238035 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0235262 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0229763 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0228483 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0222665 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.022245 |
| TXNIP | thioredoxin interacting protein | -0.0221842 |
| RPS8 | ribosomal protein S8 | -0.0221111 |
| RYBP | RING1 and YY1 binding protein | -0.0219315 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0218387 |
| ASPH | aspartate beta-hydroxylase | -0.0217542 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0216592 |
| RPL5 | ribosomal protein L5 | -0.021588 |
| RPL32 | ribosomal protein L32 | -0.0212993 |
| OPTN | optineurin | -0.0207898 |
| HLA-B | major histocompatibility complex, class I, B | -0.020494 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0204868 |
| TMSB4X | thymosin beta 4, X-linked | -0.0203453 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0201698 |
| MAP4 | microtubule-associated protein 4 | -0.0200982 |
| CALD1 | caldesmon 1 | -0.0199502 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0199415 |
| GOLGA4 | golgin A4 | -0.0194918 |
| RPS17 | ribosomal protein S17 | -0.0192537 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0192009 |
| B2M | beta-2-microglobulin | -0.018983 |
| RPL19 | ribosomal protein L19 | -0.0189129 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0187658 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.018691 |
| UBC | ubiquitin C | -0.0185559 |
| TFG | TRK-fused gene | -0.0184925 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0183357 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0182121 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0181706 |
| POTEF | POTE ankyrin domain family, member F | -0.0180074 |
| RPL12 | ribosomal protein L12 | -0.0180068 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.017955 |
| MX1 | MX dynamin-like GTPase 1 | -0.017732 |
| PLIN2 | perilipin 2 | -0.0175738 |
| HELZ | helicase with zinc finger | -0.0175294 |
| SNX3 | sorting nexin 3 | -0.0174735 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0174429 |
| RPS23 | ribosomal protein S23 | -0.0173664 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.017188 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0170788 |
| RPL21 | ribosomal protein L21 | -0.0169324 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.016918 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.016909 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0167641 |
| FAM13A | family with sequence similarity 13, member A | -0.0167244 |
| RNF145 | ring finger protein 145 | -0.0164857 |
| JMJD1C | jumonji domain containing 1C | -0.0160223 |
