| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.188688 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.148785 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0978949 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0925164 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0767705 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0733161 |
| ATP13A3 | ATPase type 13A3 | 0.0730287 |
| STC1 | stanniocalcin 1 | 0.0719335 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0656026 |
| IL6 | interleukin 6 | 0.0569318 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0508986 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.050842 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0493806 |
| YEATS2 | YEATS domain containing 2 | 0.0483576 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0466557 |
| FOXJ3 | forkhead box J3 | 0.0459169 |
| FNIP1 | folliculin interacting protein 1 | 0.0444326 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0424145 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0419726 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.041771 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0416325 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0414953 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0409366 |
| EGR1 | early growth response 1 | 0.0408833 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0404365 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0403369 |
| C1D | C1D nuclear receptor corepressor | 0.0397861 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.039639 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0394145 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0391811 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0391341 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0389591 |
| MYADM | myeloid-associated differentiation marker | 0.0386846 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.038257 |
| STK10 | serine/threonine kinase 10 | 0.0365717 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0364282 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0358514 |
| ARRDC3 | arrestin domain containing 3 | 0.0355922 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0351957 |
| NDRG1 | N-myc downstream regulated 1 | 0.0351196 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0350461 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0349622 |
| TMEM165 | transmembrane protein 165 | 0.0345999 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0345312 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0339779 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0339696 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0338425 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0332883 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0332557 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.033159 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0330126 |
| YTHDC1 | YTH domain containing 1 | 0.0325323 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0323176 |
| OXSR1 | oxidative stress responsive 1 | 0.0322656 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0320626 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0319991 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0319648 |
| L1CAM | L1 cell adhesion molecule | 0.0316142 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0315353 |
| TANK | TRAF family member-associated NFKB activator | 0.0309963 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.030872 |
| FAM13A | family with sequence similarity 13, member A | 0.0305686 |
| VEGFA | vascular endothelial growth factor A | 0.0303818 |
| INSIG2 | insulin induced gene 2 | 0.0302682 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0299032 |
| TMEM263 | transmembrane protein 263 | 0.0295627 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0293596 |
| COG6 | component of oligomeric golgi complex 6 | 0.0291959 |
| SRP72 | signal recognition particle 72kDa | 0.0288155 |
| SRP54 | signal recognition particle 54kDa | 0.0287849 |
| COG5 | component of oligomeric golgi complex 5 | 0.0286179 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0285215 |
| SFTPA2 | surfactant protein A2 | 0.0282868 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.028035 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0279599 |
| DIDO1 | death inducer-obliterator 1 | 0.0279325 |
| USP48 | ubiquitin specific peptidase 48 | 0.0276579 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0276033 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0274749 |
| LASP1 | LIM and SH3 protein 1 | 0.0273272 |
| TNRC6A | trinucleotide repeat containing 6A | 0.027268 |
| YME1L1 | YME1-like 1 ATPase | 0.0271092 |
| SUCO | SUN domain containing ossification factor | 0.0271082 |
| PCNX1 | pecanex 1 | 0.0270341 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | 0.0269283 |
| TNPO3 | transportin 3 | 0.0267423 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0267376 |
| USP15 | ubiquitin specific peptidase 15 | 0.0267015 |
| ANLN | anillin, actin binding protein | 0.0267005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.026635 |
| COPA | coatomer protein complex, subunit alpha | 0.0266037 |
| MMP2 | matrix metallopeptidase 2 | 0.0265506 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0261268 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.0260178 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0259956 |
| FAM13B | family with sequence similarity 13, member B | 0.0259394 |
| PARD3 | par-3 family cell polarity regulator | 0.0258952 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0258175 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.025814 |
| MT2A | metallothionein 2A | 0.0254868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.248398 |
| TMSB10 | thymosin beta 10 | -0.205128 |
| VIM | vimentin | -0.143352 |
| FN1 | fibronectin 1 | -0.109168 |
| COL1A1 | collagen, type I, alpha 1 | -0.107164 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0971565 |
| PTMA | prothymosin, alpha | -0.096759 |
| CALD1 | caldesmon 1 | -0.0898869 |
| COL1A2 | collagen, type I, alpha 2 | -0.0875719 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0786293 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.078485 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0758267 |
| CD44 | CD44 molecule (Indian blood group) | -0.075249 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.073317 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0695835 |
| CDK6 | cyclin-dependent kinase 6 | -0.069466 |
| AHNAK | AHNAK nucleoprotein | -0.0667605 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0657805 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0623417 |
| ENO1 | enolase 1, (alpha) | -0.0601576 |
| POTEF | POTE ankyrin domain family, member F | -0.0592525 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0591934 |
| RRBP1 | ribosome binding protein 1 | -0.0578898 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0568446 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0563711 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0555891 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0516693 |
| SDC4 | syndecan 4 | -0.0513602 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0505093 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0490285 |
| CALU | calumenin | -0.0485417 |
| DST | dystonin | -0.0482449 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0478453 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0468681 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0449143 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0448153 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0446677 |
| RTN4 | reticulon 4 | -0.0441027 |
| RAD51B | RAD51 paralog B | -0.0440126 |
| GLIS3 | GLIS family zinc finger 3 | -0.0428014 |
| VEGFC | vascular endothelial growth factor C | -0.0427768 |
| PRKCA | protein kinase C, alpha | -0.0422979 |
| ASPH | aspartate beta-hydroxylase | -0.0421921 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0420654 |
| ATXN1 | ataxin 1 | -0.0382339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.037505 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0374887 |
| TPM4 | tropomyosin 4 | -0.0373559 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0366303 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0365859 |
| MYO10 | myosin X | -0.0362362 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0356889 |
| TXNIP | thioredoxin interacting protein | -0.0355468 |
| MEF2A | myocyte enhancer factor 2A | -0.0352791 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0346725 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.034333 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0341478 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0341285 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0339161 |
| COL4A2 | collagen, type IV, alpha 2 | -0.033568 |
| COL5A1 | collagen, type V, alpha 1 | -0.0333995 |
| UBC | ubiquitin C | -0.0329956 |
| FBN1 | fibrillin 1 | -0.0327338 |
| PLCB4 | phospholipase C, beta 4 | -0.0326993 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0325955 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0325737 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0325523 |
| CDH13 | cadherin 13 | -0.0322808 |
| MYLK | myosin light chain kinase | -0.0322549 |
| MYOF | myoferlin | -0.0317014 |
| PRELID2 | PRELI domain containing 2 | -0.0316543 |
| WTAP | Wilms tumor 1 associated protein | -0.0312824 |
| PRSS23 | protease, serine, 23 | -0.0312726 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0312662 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311789 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0307723 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.030513 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0301074 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | -0.0300348 |
| TNS3 | tensin 3 | -0.0297023 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0296419 |
| COL5A2 | collagen, type V, alpha 2 | -0.0295078 |
| MAP4 | microtubule-associated protein 4 | -0.0291181 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0289669 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0287135 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.028343 |
| ITGAV | integrin, alpha V | -0.0283096 |
| QKI | QKI, KH domain containing, RNA binding | -0.0282918 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0281133 |
| ACTG1 | actin gamma 1 | -0.0278386 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0277706 |
| TMSB4X | thymosin beta 4, X-linked | -0.0277514 |
| TPM1 | tropomyosin 1 (alpha) | -0.0276217 |
| GSE1 | Gse1 coiled-coil protein | -0.0271951 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0270265 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0268856 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0267499 |
| CLIC4 | chloride intracellular channel 4 | -0.0265803 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0265002 |
| EXOC4 | exocyst complex component 4 | -0.026473 |