| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pimozide_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.441251 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0997211 |
| LDHA | lactate dehydrogenase A | 0.096268 |
| PKM | pyruvate kinase, muscle | 0.0762041 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0716677 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0684555 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0641156 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0602911 |
| EGR1 | early growth response 1 | 0.0556753 |
| NUP58 | nucleoporin 58 | 0.0525362 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0507531 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0475069 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0474106 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0444258 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0423867 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0419999 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.041352 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0405439 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0397708 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0371692 |
| RPL4 | ribosomal protein L4 | 0.0362137 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0356772 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0353529 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0348459 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0333673 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0333627 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0325409 |
| ATP13A3 | ATPase type 13A3 | 0.0325333 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0312644 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0308928 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.030328 |
| HDLBP | high density lipoprotein binding protein | 0.0300388 |
| INSIG1 | insulin induced gene 1 | 0.0285263 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0283794 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0283492 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.027875 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0278096 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0277748 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0277682 |
| NUP153 | nucleoporin 153kDa | 0.0277296 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0275018 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0274746 |
| TTK | TTK protein kinase | 0.0268609 |
| NUP98 | nucleoporin 98kDa | 0.0265036 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0264469 |
| CCDC88A | coiled-coil domain containing 88A | 0.0261848 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0258521 |
| EXOC5 | exocyst complex component 5 | 0.0258405 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0257648 |
| PER1 | period circadian clock 1 | 0.0256581 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0254973 |
| SETD5 | SET domain containing 5 | 0.0252916 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0249261 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0248059 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0247371 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0245624 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0239946 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0237046 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0236793 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0235404 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.023496 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0233203 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0233143 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0229541 |
| BSG | basigin (Ok blood group) | 0.0228614 |
| SPAG9 | sperm associated antigen 9 | 0.022814 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0227144 |
| SEC24A | SEC24 family member A | 0.0225325 |
| FLNA | filamin A, alpha | 0.0224672 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0224186 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0223553 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.0222232 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0221543 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0220539 |
| GPR107 | G protein-coupled receptor 107 | 0.0219762 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0219085 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0218654 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0216467 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0216261 |
| MCL1 | myeloid cell leukemia 1 | 0.0215742 |
| HELZ | helicase with zinc finger | 0.0214787 |
| NONO | non-POU domain containing, octamer-binding | 0.0214443 |
| ZNF207 | zinc finger protein 207 | 0.0212938 |
| IPO11 | importin 11 | 0.0212753 |
| ZFR | zinc finger RNA binding protein | 0.0211122 |
| CCNL1 | cyclin L1 | 0.0211081 |
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.0210572 |
| ATXN2L | ataxin 2-like | 0.0208226 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0205988 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0203201 |
| OGFRL1 | opioid growth factor receptor-like 1 | 0.0202592 |
| SEPTIN2 | septin 2 | 0.0202243 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0199013 |
| QSER1 | glutamine and serine rich 1 | 0.0197919 |
| PDS5A | PDS5 cohesin associated factor A | 0.0197235 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.019707 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0196248 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 0.019621 |
| TBK1 | TANK-binding kinase 1 | 0.0195874 |
| TNPO1 | transportin 1 | 0.0194994 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.132626 |
| VIM | vimentin | -0.104402 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104113 |
| TMSB10 | thymosin beta 10 | -0.089965 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0797122 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0787656 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0688937 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0687159 |
| AHNAK | AHNAK nucleoprotein | -0.0671832 |
| SMYD3 | SET and MYND domain containing 3 | -0.0667566 |
| DST | dystonin | -0.064068 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0636046 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0615135 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0589614 |
| PTMA | prothymosin, alpha | -0.0556194 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0545855 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0539591 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0526904 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0523977 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0519789 |
| ATM | ATM serine/threonine kinase | -0.0509041 |
| MT2A | metallothionein 2A | -0.0480027 |
| GOLGA4 | golgin A4 | -0.0477937 |
| ASPH | aspartate beta-hydroxylase | -0.0475948 |
| HMGA2 | high mobility group AT-hook 2 | -0.0475718 |
| ANO6 | anoctamin 6 | -0.0445543 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0425043 |
| RORA | RAR-related orphan receptor A | -0.0424006 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0418812 |
| GOLGB1 | golgin B1 | -0.04068 |
| SDC4 | syndecan 4 | -0.0398743 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0393019 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0385963 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0385946 |
| PYGL | phosphorylase, glycogen, liver | -0.0379561 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0379019 |
| TPM4 | tropomyosin 4 | -0.0373869 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0368044 |
| FMN1 | formin 1 | -0.0366334 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0364892 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0361634 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0358915 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0350482 |
| OGA | O-GlcNAcase | -0.034929 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0346581 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0344905 |
| RBM39 | RNA binding motif protein 39 | -0.034485 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0344724 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0341807 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0339067 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0337016 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0331028 |
| CPNE1 | copine I | -0.033062 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0327601 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0326234 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0325911 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0322022 |
| PTK2 | protein tyrosine kinase 2 | -0.0320211 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0316815 |
| KIF5B | kinesin family member 5B | -0.0311708 |
| CEP57 | centrosomal protein 57kDa | -0.0306242 |
| RPS25 | ribosomal protein S25 | -0.0304546 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0299179 |
| LMO7 | LIM domain 7 | -0.0297814 |
| EXOC4 | exocyst complex component 4 | -0.0296165 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0295987 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0295113 |
| NDRG1 | N-myc downstream regulated 1 | -0.0293752 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0293672 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0293036 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0292826 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0292437 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0290794 |
| RPS12 | ribosomal protein S12 | -0.028921 |
| SYNJ2 | synaptojanin 2 | -0.0288022 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.0284923 |
| ANGPTL4 | angiopoietin-like 4 | -0.0284733 |
| RPS17 | ribosomal protein S17 | -0.0284691 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0280533 |
| VCL | vinculin | -0.0280501 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0279206 |
| ATP9B | ATPase, class II, type 9B | -0.0278343 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0277573 |
| SMAD3 | SMAD family member 3 | -0.0276971 |
| RPLP0 | ribosomal protein, large, P0 | -0.0273523 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0271969 |
| RAI14 | retinoic acid induced 14 | -0.0271161 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0270711 |
| H3-3B | H3.3 histone B | -0.0268702 |
| CD2AP | CD2-associated protein | -0.0268028 |
| BBX | bobby sox homolog (Drosophila) | -0.0267888 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0267543 |
| MYO9B | myosin IXB | -0.0266576 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0266502 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0264919 |
| VMP1 | vacuole membrane protein 1 | -0.0263948 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0263535 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0263026 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0261067 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0259646 |
