| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pimozide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pimozide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.218813 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.200696 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.137582 |
| EXT1 | exostosin glycosyltransferase 1 | 0.11302 |
| OSMR | oncostatin M receptor | 0.0958528 |
| NRP1 | neuropilin 1 | 0.0792346 |
| TMEM156 | transmembrane protein 156 | 0.0777362 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0686725 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0596152 |
| RUNX2 | runt-related transcription factor 2 | 0.0527352 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0486821 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0484431 |
| FN1 | fibronectin 1 | 0.0479951 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0474152 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0460586 |
| AHR | aryl hydrocarbon receptor | 0.0450096 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0444877 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.044108 |
| FLNA | filamin A, alpha | 0.0437363 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0435028 |
| CD44 | CD44 molecule (Indian blood group) | 0.0388313 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0381683 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0377938 |
| ETNK1 | ethanolamine kinase 1 | 0.0377568 |
| CLTC | clathrin, heavy chain (Hc) | 0.0376216 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0371688 |
| PKM | pyruvate kinase, muscle | 0.036647 |
| KSR1 | kinase suppressor of ras 1 | 0.0359395 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0355571 |
| TPR | translocated promoter region, nuclear basket protein | 0.034397 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0342787 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0342177 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0338618 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0338386 |
| NPC1 | Niemann-Pick disease, type C1 | 0.033833 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0329482 |
| WDR26 | WD repeat domain 26 | 0.0325944 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0323859 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0316512 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0314775 |
| ITGB5 | integrin, beta 5 | 0.0313067 |
| IL6ST | interleukin 6 signal transducer | 0.0311592 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0308727 |
| KLHL5 | kelch-like family member 5 | 0.0303441 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0297668 |
| CAB39 | calcium binding protein 39 | 0.0296797 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.029663 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0295285 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0293469 |
| NTN4 | netrin 4 | 0.0290504 |
| MAP1B | microtubule-associated protein 1B | 0.0289069 |
| COG5 | component of oligomeric golgi complex 5 | 0.0276516 |
| HOMER2 | homer scaffolding protein 2 | 0.0275591 |
| ANKRD17 | ankyrin repeat domain 17 | 0.027508 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0273658 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0273328 |
| PLPP6 | phospholipid phosphatase 6 | 0.0271263 |
| PELO | pelota homolog (Drosophila) | 0.0270929 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0267981 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.026628 |
| GLIS3 | GLIS family zinc finger 3 | 0.0264861 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0262736 |
| TGM2 | transglutaminase 2 | 0.0261711 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.026085 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.025855 |
| ETV6 | ets variant 6 | 0.0257866 |
| EREG | epiregulin | 0.0256245 |
| FNBP1 | formin binding protein 1 | 0.025551 |
| SMAD3 | SMAD family member 3 | 0.0255009 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253504 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0253404 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0253341 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0251016 |
| SFTPA2 | surfactant protein A2 | 0.0250118 |
| SMOX | spermine oxidase | 0.0249744 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0247492 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0246917 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0246569 |
| FAM3C | family with sequence similarity 3, member C | 0.0244073 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0242157 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0242061 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.023946 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0238123 |
| SYNJ2 | synaptojanin 2 | 0.0237309 |
| ADD3 | adducin 3 (gamma) | 0.0237234 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0232061 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0231606 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0227299 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0224642 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0223693 |
| FAF2 | Fas associated factor family member 2 | 0.0215364 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0212031 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.02114 |
| COPA | coatomer protein complex, subunit alpha | 0.0211111 |
| RAB31 | RAB31, member RAS oncogene family | 0.0210252 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0209564 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0203464 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0202071 |
| SETD5 | SET domain containing 5 | 0.0201774 |
| CDC73 | cell division cycle 73 | 0.0200955 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.134513 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0816737 |
| PTMA | prothymosin, alpha | -0.0807868 |
| TMSB10 | thymosin beta 10 | -0.0733902 |
| ASPH | aspartate beta-hydroxylase | -0.0628212 |
| MT2A | metallothionein 2A | -0.0625547 |
| HMGA2 | high mobility group AT-hook 2 | -0.0591111 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0572809 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0536706 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0519955 |
| HLA-B | major histocompatibility complex, class I, B | -0.0502634 |
| INTS6 | integrator complex subunit 6 | -0.045116 |
| FTL | ferritin, light polypeptide | -0.0426598 |
| TMSB4X | thymosin beta 4, X-linked | -0.0422454 |
| S100A10 | S100 calcium binding protein A10 | -0.0409125 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0376608 |
| RPS19 | ribosomal protein S19 | -0.0365184 |
| AHNAK | AHNAK nucleoprotein | -0.0340283 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.033806 |
| EFNA5 | ephrin-A5 | -0.0333319 |
| AEBP2 | AE binding protein 2 | -0.0333221 |
| RPS6 | ribosomal protein S6 | -0.0329471 |
| LMNA | lamin A/C | -0.0329057 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0321767 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0321056 |
| IER3 | immediate early response 3 | -0.0313632 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0313629 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0313365 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0310168 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0308083 |
| RPS29 | ribosomal protein S29 | -0.0302343 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0297483 |
| VIM | vimentin | -0.02877 |
| RPS8 | ribosomal protein S8 | -0.0284085 |
| RPL35A | ribosomal protein L35a | -0.0281479 |
| RPS21 | ribosomal protein S21 | -0.0274542 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0272836 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0269597 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0269514 |
| MYOF | myoferlin | -0.0264174 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0261639 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.026043 |
| LRRC23 | leucine rich repeat containing 23 | -0.0259549 |
| FLNB | filamin B, beta | -0.0253077 |
| CTBP2 | C-terminal binding protein 2 | -0.0250357 |
| RAI14 | retinoic acid induced 14 | -0.0246523 |
| B2M | beta-2-microglobulin | -0.0244098 |
| CANX | calnexin | -0.0242326 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0240583 |
| GNAS | GNAS complex locus | -0.0237769 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.023007 |
| RPL23 | ribosomal protein L23 | -0.0229784 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0228053 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0225168 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0221219 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0221214 |
| RPS3 | ribosomal protein S3 | -0.0220102 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0216932 |
| RPS27A | ribosomal protein S27a | -0.0216829 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0216779 |
| TENM4 | teneurin transmembrane protein 4 | -0.0215942 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0215167 |
| RAD51B | RAD51 paralog B | -0.021426 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0211015 |
| RPLP1 | ribosomal protein, large, P1 | -0.0208271 |
| RPL36 | ribosomal protein L36 | -0.0207958 |
| CADM1 | cell adhesion molecule 1 | -0.0205159 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0204635 |
| RPS24 | ribosomal protein S24 | -0.0203988 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0203207 |
| FHIT | fragile histidine triad | -0.020207 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0202042 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0201762 |
| RPL12 | ribosomal protein L12 | -0.0201388 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0200964 |
| FAM13A | family with sequence similarity 13, member A | -0.0200042 |
| MCL1 | myeloid cell leukemia 1 | -0.0197027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0194533 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0194102 |
| RPL31 | ribosomal protein L31 | -0.0193004 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0190952 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0190806 |
| RPLP2 | ribosomal protein, large, P2 | -0.019055 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0190109 |
| RPL38 | ribosomal protein L38 | -0.0190104 |
| ENO1 | enolase 1, (alpha) | -0.018914 |
| EZR | ezrin | -0.0187751 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0187196 |
| ANXA2 | annexin A2 | -0.0183733 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0183505 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0182307 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0182036 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.018155 |
| RPS27 | ribosomal protein S27 | -0.0180689 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0180677 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0180583 |
| RPS23 | ribosomal protein S23 | -0.0178663 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0177475 |
| JUN | jun proto-oncogene | -0.0176382 |
| S100A9 | S100 calcium binding protein A9 | -0.0175961 |
