Pineoblastoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A pineal gland neoplasm located_in the brain. (Human Disease Ontology, DOID_1664)
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Genes

115 genes co-occuring with the disease Pineoblastoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
DICER1 dicer 1, ribonuclease type III 2.851
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 2.844
FOXR2 forkhead box R2 2.723
SYP synaptophysin 2.386
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 2.301
DROSHA drosha, ribonuclease type III 2.281
PDE4DIP phosphodiesterase 4D interacting protein 2.116
SHH sonic hedgehog 2.056
CRX cone-rod homeobox 1.976
DGCR8 DGCR8 microprocessor complex subunit 1.974
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.918
SAG S-antigen; retina and pineal gland (arrestin) 1.821
OLIG2 oligodendrocyte lineage transcription factor 2 1.807
GFAP glial fibrillary acidic protein 1.783
TP53 tumor protein p53 1.764
PTPRS protein tyrosine phosphatase, receptor type, S 1.751
AFP alpha-fetoprotein 1.751
ALPP alkaline phosphatase, placental 1.746
OR4C12 olfactory receptor, family 4, subfamily C, member 12 1.745
ENO2 enolase 2 (gamma, neuronal) 1.735
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.726
NF1 neurofibromin 1 1.725
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 1.724
ASMT acetylserotonin O-methyltransferase 1.683
CD99 CD99 molecule 1.669
MN1 meningioma (disrupted in balanced translocation) 1 1.581
EWSR1 EWS RNA-binding protein 1 1.55
LIN28A lin-28 homolog A (C. elegans) 1.544
RBP3 retinol binding protein 3, interstitial 1.534
ATRX alpha thalassemia/mental retardation syndrome X-linked 1.528
CD99L2 CD99 molecule-like 2 1.525
H3-3A H3.3 histone A 1.52
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.509
KIAA1549 KIAA1549 1.506
OTX2 orthodenticle homeobox 2 1.505
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 1.499
TTYH1 tweety family member 1 1.482
MGMT O-6-methylguanine-DNA methyltransferase 1.455
CHGA chromogranin A 1.436
TERT telomerase reverse transcriptase 1.428
RB1 retinoblastoma 1 1.417
PTCH1 patched 1 1.384
PCDHGA3 protocadherin gamma subfamily A, 3 1.383
NUTM1 NUT midline carcinoma, family member 1 1.376
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.372
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.372
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.365
POU4F2 POU class 4 homeobox 2 1.364
SIAH3 siah E3 ubiquitin protein ligase family member 3 1.355
PLAGL2 pleiomorphic adenoma gene-like 2 1.353
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 1.352
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.35
VGLL2 vestigial-like family member 2 1.346
TARBP1 TAR (HIV-1) RNA binding protein 1 1.339
PTEN phosphatase and tensin homolog 1.327
RUNDC3A RUN domain containing 3A 1.31
SCGN secretagogin, EF-hand calcium binding protein 1.302
EGFR epidermal growth factor receptor 1.29
PHOX2B paired-like homeobox 2b 1.285
EZHIP EZH inhibitory protein 1.284
CDKN2A cyclin-dependent kinase inhibitor 2A 1.283
H3-3B H3.3 histone B 1.282
NFIB nuclear factor I/B 1.282
SUFU suppressor of fused homolog (Drosophila) 1.279
XPO5 exportin 5 1.276
PRR23A proline rich 23A 1.269
PRAME preferentially expressed antigen in melanoma 1.26
ANKRD36C ankyrin repeat domain 36C 1.249
LIPN lipase, family member N 1.239
TYR tyrosinase 1.233
MYOG myogenin (myogenic factor 4) 1.231
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.22
INTS13 integrator complex subunit 13 1.218
NF2 neurofibromin 2 (merlin) 1.2
SALL4 spalt-like transcription factor 4 1.195
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.193
SOX2 SRY (sex determining region Y)-box 2 1.191
NES nestin 1.19
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) 1.19
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 1.178
CCNB3 cyclin B3 1.176
PDE4D phosphodiesterase 4D, cAMP-specific 1.175
SOX10 SRY (sex determining region Y)-box 10 1.173
CADPS Ca++-dependent secretion activator 1.156
H3C3 H3 clustered histone 3 1.147
ANKRD36 ankyrin repeat domain 36 1.129
PPP6C protein phosphatase 6, catalytic subunit 1.129
H3C12 H3 clustered histone 12 1.126
NHLH1 nescient helix loop helix 1 1.108
YAP1 Yes-associated protein 1 1.105
PRDM6 PR domain containing 6 1.103
RGS16 regulator of G-protein signaling 16 1.101
PAX3 paired box 3 1.096
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.092
CCND1 cyclin D1 1.092
WT1 Wilms tumor 1 1.089
RLBP1 retinaldehyde binding protein 1 1.087
HINFP histone H4 transcription factor 1.082
TUBB3 tubulin, beta 3 class III 1.068
POU5F1 POU class 5 homeobox 1 1.066
HOXD13 homeobox D13 1.063
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.062
RFX3 regulatory factor X, 3 (influences HLA class II expression) 1.06
MUTYH mutY homolog 1.048
KRT75 keratin 75, type II 1.045
GLI2 GLI family zinc finger 2 1.039
CHRDL2 chordin-like 2 1.035
SNCAIP synuclein, alpha interacting protein 1.021
TACC1 transforming, acidic coiled-coil containing protein 1 1.02
H3C2 H3 clustered histone 2 1.018
RHO rhodopsin 1.012
GPC2 glypican 2 1.012
MYB v-myb avian myeloblastosis viral oncogene homolog 1.011
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.003
CIC capicua transcriptional repressor 1.002