Pioglitazone Gene Set

Dataset	HMDB Metabolites of Enzymes
Category	physical interactions
Type	metabolite
Description	A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity. (Chemical Entities of Biological Interest Ontology, CHEBI_8228)
External Link	http://www.hmdb.ca/metabolites/HMDB15264
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Genes

9 interacting proteins for the Pioglitazone metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol	Name
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4
PPARG	peroxisome proliferator-activated receptor gamma
PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SLCO1B1	solute carrier organic anion transporter family, member 1B1
SLCO1B3	solute carrier organic anion transporter family, member 1B3