| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pioglitazone_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.224193 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.13286 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0996161 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0908608 |
| FBN1 | fibrillin 1 | 0.0851972 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0710366 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0699757 |
| CANX | calnexin | 0.0655448 |
| SEPTIN9 | septin 9 | 0.0643759 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0600757 |
| LOXL2 | lysyl oxidase-like 2 | 0.0586662 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0585666 |
| COL1A2 | collagen, type I, alpha 2 | 0.0551374 |
| APP | amyloid beta (A4) precursor protein | 0.0536452 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0515371 |
| CALR | calreticulin | 0.050472 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0502321 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0501905 |
| COL5A1 | collagen, type V, alpha 1 | 0.044504 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0433171 |
| GOLGA4 | golgin A4 | 0.0424067 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0419295 |
| CD109 | CD109 molecule | 0.0414349 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0412748 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0392217 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0392081 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0377286 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0356082 |
| COL5A2 | collagen, type V, alpha 2 | 0.0340047 |
| COL3A1 | collagen, type III, alpha 1 | 0.0339379 |
| MYOF | myoferlin | 0.0336332 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0336092 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.033525 |
| YEATS2 | YEATS domain containing 2 | 0.0330808 |
| FNIP1 | folliculin interacting protein 1 | 0.0330134 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0319769 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0319617 |
| AUTS2 | autism susceptibility candidate 2 | 0.0319028 |
| OPTN | optineurin | 0.0318176 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0316841 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0316392 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0313722 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.031127 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0309606 |
| SBF2 | SET binding factor 2 | 0.030549 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0304023 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0303526 |
| AHNAK | AHNAK nucleoprotein | 0.0299593 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0295074 |
| MSN | moesin | 0.0286175 |
| EZR | ezrin | 0.0274957 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0272505 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0271355 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0270006 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0265052 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0264076 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0263278 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0261941 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0258846 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.025613 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0251469 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0247132 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0244356 |
| EGFR | epidermal growth factor receptor | 0.0242705 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0241939 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0241765 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0241321 |
| NAV2 | neuron navigator 2 | 0.0240753 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0239358 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0238668 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0237104 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.023644 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.023568 |
| AFDN | afadin, adherens junction formation factor | 0.0235481 |
| UBXN7 | UBX domain protein 7 | 0.0235462 |
| DST | dystonin | 0.0235183 |
| FAM107B | family with sequence similarity 107, member B | 0.0234341 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.022991 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0229092 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0228552 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0227718 |
| PFKP | phosphofructokinase, platelet | 0.0227394 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0224232 |
| CEP170 | centrosomal protein 170kDa | 0.0223404 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0221832 |
| MMP12 | matrix metallopeptidase 12 | 0.0221679 |
| GANAB | glucosidase, alpha; neutral AB | 0.0221612 |
| FAM219A | family with sequence similarity 219, member A | 0.0220463 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218147 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0218086 |
| COPA | coatomer protein complex, subunit alpha | 0.0217411 |
| XPO1 | exportin 1 | 0.0217189 |
| VEGFA | vascular endothelial growth factor A | 0.0216282 |
| PLEC | plectin | 0.021604 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0213919 |
| ANXA1 | annexin A1 | 0.0212762 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0212374 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.021125 |
| PTK2 | protein tyrosine kinase 2 | 0.0210449 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0210214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.287757 |
| TMSB10 | thymosin beta 10 | -0.234218 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.165454 |
| MT2A | metallothionein 2A | -0.155241 |
| VIM | vimentin | -0.137475 |
| S100A10 | S100 calcium binding protein A10 | -0.0950257 |
| UBC | ubiquitin C | -0.0908043 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0674207 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0664524 |
| ACTG1 | actin gamma 1 | -0.0592452 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0583007 |
| POTEF | POTE ankyrin domain family, member F | -0.0567717 |
| S100A6 | S100 calcium binding protein A6 | -0.056635 |
| LOX | lysyl oxidase | -0.0564045 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0519718 |
| MT1X | metallothionein 1X | -0.0485174 |
| HLA-B | major histocompatibility complex, class I, B | -0.0483237 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0472307 |
| RPL28 | ribosomal protein L28 | -0.0464799 |
| TMSB4X | thymosin beta 4, X-linked | -0.0457328 |
| LMNA | lamin A/C | -0.0440999 |
| S100A4 | S100 calcium binding protein A4 | -0.043813 |
| MAP1B | microtubule-associated protein 1B | -0.0378884 |
| CSTB | cystatin B (stefin B) | -0.0369722 |
| MX2 | MX dynamin-like GTPase 2 | -0.0360406 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0345191 |
| RPS27A | ribosomal protein S27a | -0.0343816 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0341872 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0341054 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0335393 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0333451 |
| HLA-C | major histocompatibility complex, class I, C | -0.0331303 |
| SP100 | SP100 nuclear antigen | -0.0319967 |
| RIGI | RNA sensor RIG-I | -0.0318714 |
| RPL37A | ribosomal protein L37a | -0.0318184 |
| RPLP1 | ribosomal protein, large, P1 | -0.031089 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0303895 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0301758 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0298846 |
| RPS24 | ribosomal protein S24 | -0.0296894 |
| RPS3 | ribosomal protein S3 | -0.0295375 |
| RPL36 | ribosomal protein L36 | -0.0293577 |
| PTMA | prothymosin, alpha | -0.0292385 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0291523 |
| RPL19 | ribosomal protein L19 | -0.0290466 |
| RPL34 | ribosomal protein L34 | -0.0290158 |
| RPL23 | ribosomal protein L23 | -0.0288092 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0286428 |
| SQSTM1 | sequestosome 1 | -0.0282618 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.028223 |
| PKM | pyruvate kinase, muscle | -0.0281386 |
| NAV1 | neuron navigator 1 | -0.0280911 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0277366 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0274146 |
| MEIS2 | Meis homeobox 2 | -0.0273005 |
| SEC61G | Sec61 gamma subunit | -0.0271797 |
| RPL26 | ribosomal protein L26 | -0.0271523 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0267535 |
| RPS19 | ribosomal protein S19 | -0.026479 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0261618 |
| PFN1 | profilin 1 | -0.0261394 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0255565 |
| RPS11 | ribosomal protein S11 | -0.0255324 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0251041 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0249357 |
| RPS5 | ribosomal protein S5 | -0.024901 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0248926 |
| RPL35A | ribosomal protein L35a | -0.0247932 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0243659 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0242933 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0241634 |
| S100A11 | S100 calcium binding protein A11 | -0.0240395 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0238703 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0236797 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.023666 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0236171 |
| CCND1 | cyclin D1 | -0.023611 |
| ARF1 | ADP-ribosylation factor 1 | -0.0234212 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0234195 |
| FTL | ferritin, light polypeptide | -0.0232176 |
| RPL32 | ribosomal protein L32 | -0.0230962 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0230684 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0229574 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0226642 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.0225169 |
| RACK1 | receptor for activated C kinase 1 | -0.0221067 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0218308 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.021805 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0215017 |
| RPS8 | ribosomal protein S8 | -0.0213368 |
| RPL35 | ribosomal protein L35 | -0.0212469 |
| ADAR | adenosine deaminase, RNA-specific | -0.0200942 |
| RPL12 | ribosomal protein L12 | -0.0200722 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0199885 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0199049 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0197976 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0197685 |
| RNF213 | ring finger protein 213 | -0.01972 |
| RPLP0 | ribosomal protein, large, P0 | -0.0196319 |
| NPR2 | natriuretic peptide receptor 2 | -0.0194448 |
