| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pioglitazone_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.224969 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.136878 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.102065 |
| PLAT | plasminogen activator, tissue | 0.0938544 |
| FMN1 | formin 1 | 0.0838357 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.062195 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0608094 |
| VCL | vinculin | 0.0600243 |
| SMAD3 | SMAD family member 3 | 0.0556146 |
| YEATS2 | YEATS domain containing 2 | 0.0550983 |
| SEPTIN9 | septin 9 | 0.0538315 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0519171 |
| NRG1 | neuregulin 1 | 0.0518993 |
| MCL1 | myeloid cell leukemia 1 | 0.0500735 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0498137 |
| CENPF | centromere protein F, 350/400kDa | 0.0496079 |
| ZNF148 | zinc finger protein 148 | 0.0493397 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0473246 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0471123 |
| CANX | calnexin | 0.0458953 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0447261 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0446476 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0442585 |
| MEIS2 | Meis homeobox 2 | 0.0437935 |
| ENO1 | enolase 1, (alpha) | 0.0430401 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0417395 |
| COL4A1 | collagen, type IV, alpha 1 | 0.041646 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0414078 |
| PGK1 | phosphoglycerate kinase 1 | 0.0412333 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0407329 |
| NDRG1 | N-myc downstream regulated 1 | 0.0407047 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0402672 |
| DST | dystonin | 0.0398335 |
| ASPH | aspartate beta-hydroxylase | 0.0389462 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0378853 |
| PFKP | phosphofructokinase, platelet | 0.0366579 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0363708 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0362549 |
| NAV2 | neuron navigator 2 | 0.0359557 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0357336 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0357114 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0355056 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0354837 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0354345 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0351275 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0347339 |
| SCG2 | secretogranin II | 0.0346544 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0341264 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0340312 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0337312 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0335639 |
| LPIN1 | lipin 1 | 0.0334019 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0332003 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0330191 |
| USP34 | ubiquitin specific peptidase 34 | 0.0325434 |
| FNDC3B | fibronectin type III domain containing 3B | 0.032535 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0323225 |
| CCNY | cyclin Y | 0.0322432 |
| VEGFA | vascular endothelial growth factor A | 0.0321898 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0321529 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0321211 |
| COL3A1 | collagen, type III, alpha 1 | 0.0314305 |
| APP | amyloid beta (A4) precursor protein | 0.0312598 |
| SETD2 | SET domain containing 2 | 0.0308674 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0308497 |
| ARRDC3 | arrestin domain containing 3 | 0.0308257 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0304292 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0303475 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0300156 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0298609 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0296823 |
| TRIB2 | tribbles pseudokinase 2 | 0.0296496 |
| COPA | coatomer protein complex, subunit alpha | 0.0296166 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0295108 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0294326 |
| PRKCE | protein kinase C, epsilon | 0.0292125 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0289658 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0289418 |
| INSIG2 | insulin induced gene 2 | 0.0288824 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0288655 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0288408 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0288318 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0285995 |
| SETD5 | SET domain containing 5 | 0.0284345 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0284199 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0282665 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0282373 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0281846 |
| FMNL2 | formin-like 2 | 0.0280813 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0280807 |
| DPH6 | diphthamine biosynthesis 6 | 0.0280023 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0278056 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0277815 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0276363 |
| NMD3 | NMD3 ribosome export adaptor | 0.027419 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0274092 |
| UBE3A | ubiquitin protein ligase E3A | 0.0271968 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0271866 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.026992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.414957 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150675 |
| ACTG1 | actin gamma 1 | -0.0882634 |
| VIM | vimentin | -0.0843241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.075412 |
| RPLP1 | ribosomal protein, large, P1 | -0.0670725 |
| RPL35A | ribosomal protein L35a | -0.0603644 |
| RPL23 | ribosomal protein L23 | -0.0593575 |
| RPL34 | ribosomal protein L34 | -0.0572831 |
| RPL19 | ribosomal protein L19 | -0.0557777 |
| RPS6 | ribosomal protein S6 | -0.0547512 |
| TMSB10 | thymosin beta 10 | -0.0516645 |
| COL1A1 | collagen, type I, alpha 1 | -0.050075 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0491642 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0480277 |
| MED13 | mediator complex subunit 13 | -0.0450007 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0437817 |
| PTMA | prothymosin, alpha | -0.0414812 |
| LMNA | lamin A/C | -0.0400306 |
| RPL26 | ribosomal protein L26 | -0.0393566 |
| RPL38 | ribosomal protein L38 | -0.0390348 |
| RPS24 | ribosomal protein S24 | -0.0370948 |
| QKI | QKI, KH domain containing, RNA binding | -0.0369524 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0362609 |
| PLPP1 | phospholipid phosphatase 1 | -0.0355734 |
| RPS19 | ribosomal protein S19 | -0.0355069 |
| IER3 | immediate early response 3 | -0.0338429 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0326668 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0326141 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0316138 |
| RACK1 | receptor for activated C kinase 1 | -0.0312043 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0311118 |
| AOPEP | aminopeptidase O (putative) | -0.0306793 |
| RPL36 | ribosomal protein L36 | -0.0305634 |
| RPLP0 | ribosomal protein, large, P0 | -0.0302757 |
| RPS25 | ribosomal protein S25 | -0.0301681 |
| POTEF | POTE ankyrin domain family, member F | -0.0300714 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0298989 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0291101 |
| PCM1 | pericentriolar material 1 | -0.0290725 |
| TLK2 | tousled-like kinase 2 | -0.0284202 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0282022 |
| RPL30 | ribosomal protein L30 | -0.0282004 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0274093 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0272716 |
| OGA | O-GlcNAcase | -0.0271389 |
| CCND1 | cyclin D1 | -0.026885 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0267762 |
| SYT1 | synaptotagmin I | -0.0267462 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0267123 |
| RPS16 | ribosomal protein S16 | -0.0262671 |
| SEPTIN2 | septin 2 | -0.0253576 |
| KLHL13 | kelch-like family member 13 | -0.0252744 |
| RPS27A | ribosomal protein S27a | -0.0249002 |
| RPS3 | ribosomal protein S3 | -0.0247935 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0244384 |
| GNAS | GNAS complex locus | -0.0244033 |
| RNF24 | ring finger protein 24 | -0.0243072 |
| NEK7 | NIMA-related kinase 7 | -0.0242502 |
| PARD3 | par-3 family cell polarity regulator | -0.0239248 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0238689 |
| SPAG9 | sperm associated antigen 9 | -0.0237314 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0236044 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0235015 |
| RLF | rearranged L-myc fusion | -0.0233867 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0233327 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0232374 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0231416 |
| RPS15 | ribosomal protein S15 | -0.0230518 |
| ZNF804A | zinc finger protein 804A | -0.0229591 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0229517 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.0227235 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0225541 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0223782 |
| RPS14 | ribosomal protein S14 | -0.0219596 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0218601 |
| PHIP | pleckstrin homology domain interacting protein | -0.0216989 |
| RPL35 | ribosomal protein L35 | -0.0215441 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0211088 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0210792 |
| FTL | ferritin, light polypeptide | -0.0205615 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0204486 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.02031 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0202957 |
| SSH2 | slingshot protein phosphatase 2 | -0.0201093 |
| MIS18BP1 | MIS18 binding protein 1 | -0.020073 |
| RUFY2 | RUN and FYVE domain containing 2 | -0.0199921 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0196617 |
| NRP1 | neuropilin 1 | -0.0195728 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0193802 |
| WDR45B | WD repeat domain 45B | -0.0191826 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0191686 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0191356 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0189078 |
| RTN4 | reticulon 4 | -0.0188786 |
| DENND4A | DENN/MADD domain containing 4A | -0.0187843 |
| RPL18 | ribosomal protein L18 | -0.0187376 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0187281 |
| BPTF | bromodomain PHD finger transcription factor | -0.0186751 |
| RIOK3 | RIO kinase 3 | -0.0186152 |
