| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0700037 |
| CADM1 | cell adhesion molecule 1 | 0.067358 |
| ATP13A3 | ATPase type 13A3 | 0.0658917 |
| NDRG1 | N-myc downstream regulated 1 | 0.0658908 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0622326 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0544145 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0533538 |
| ARRDC3 | arrestin domain containing 3 | 0.0524836 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0522608 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0514021 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0465312 |
| SPAG9 | sperm associated antigen 9 | 0.0451689 |
| RASA2 | RAS p21 protein activator 2 | 0.0442129 |
| FMNL2 | formin-like 2 | 0.0441836 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0422521 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0412789 |
| ZNF292 | zinc finger protein 292 | 0.0402899 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0395095 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0393324 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0380303 |
| PTK2 | protein tyrosine kinase 2 | 0.0371542 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0367695 |
| CANX | calnexin | 0.0364824 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.036129 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0352765 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0350434 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0349828 |
| ADM | adrenomedullin | 0.0339866 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0339718 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0334974 |
| CALR | calreticulin | 0.0334323 |
| CCNY | cyclin Y | 0.0334251 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0323677 |
| RLF | rearranged L-myc fusion | 0.0320549 |
| GOLGA4 | golgin A4 | 0.0320368 |
| TFG | TRK-fused gene | 0.031852 |
| MRTFA | myocardin related transcription factor A | 0.0307925 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0301812 |
| SMAD3 | SMAD family member 3 | 0.0300677 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.029627 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0295711 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0291784 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0288235 |
| SQLE | squalene epoxidase | 0.028801 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.028589 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0284873 |
| HELZ | helicase with zinc finger | 0.0283776 |
| USP3 | ubiquitin specific peptidase 3 | 0.0282518 |
| GANAB | glucosidase, alpha; neutral AB | 0.0280651 |
| PDE8A | phosphodiesterase 8A | 0.0279647 |
| WAC | WW domain containing adaptor with coiled-coil | 0.027934 |
| POSTN | periostin, osteoblast specific factor | 0.0277844 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0277211 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0275519 |
| RAB1A | RAB1A, member RAS oncogene family | 0.027219 |
| TSC22D2 | TSC22 domain family, member 2 | 0.026682 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0263354 |
| FOXJ3 | forkhead box J3 | 0.0260744 |
| HIP1 | huntingtin interacting protein 1 | 0.0255055 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0253229 |
| SUCO | SUN domain containing ossification factor | 0.0252505 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0249842 |
| XPO1 | exportin 1 | 0.0244895 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.024412 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0243511 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0240434 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0239794 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0237266 |
| QKI | QKI, KH domain containing, RNA binding | 0.0237016 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0236789 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0232652 |
| AZIN1 | antizyme inhibitor 1 | 0.0232544 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0229824 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0229258 |
| OGA | O-GlcNAcase | 0.0228713 |
| NUP58 | nucleoporin 58 | 0.0228158 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0225805 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0223691 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0222632 |
| ZNF148 | zinc finger protein 148 | 0.0218204 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0217223 |
| RYK | receptor-like tyrosine kinase | 0.0212381 |
| RHEB | Ras homolog enriched in brain | 0.0210213 |
| VEGFA | vascular endothelial growth factor A | 0.0210209 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0209606 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0207647 |
| CCNL1 | cyclin L1 | 0.0205573 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0205523 |
| APP | amyloid beta (A4) precursor protein | 0.020537 |
| NOP58 | NOP58 ribonucleoprotein | 0.0204842 |
| SRP54 | signal recognition particle 54kDa | 0.0203977 |
| RBM39 | RNA binding motif protein 39 | 0.0203149 |
| MATR3 | matrin 3 | 0.0198337 |
| PCBP2 | poly(rC) binding protein 2 | 0.0197645 |
| MLF1 | myeloid leukemia factor 1 | 0.019683 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0196829 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0194978 |
| DIAPH1 | diaphanous-related formin 1 | 0.0194782 |
| TNPO3 | transportin 3 | 0.0194 |
| COLEC11 | collectin sub-family member 11 | 0.019365 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.316763 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.182513 |
| COL1A1 | collagen, type I, alpha 1 | -0.152414 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.141599 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.106689 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0993878 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0976893 |
| FN1 | fibronectin 1 | -0.095681 |
| CDH13 | cadherin 13 | -0.0926824 |
| DPYD | dihydropyrimidine dehydrogenase | -0.08628 |
| HMGA2 | high mobility group AT-hook 2 | -0.0814783 |
| ASPH | aspartate beta-hydroxylase | -0.0811499 |
| TMSB10 | thymosin beta 10 | -0.073435 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0707367 |
| VIM | vimentin | -0.0705887 |
| FBN1 | fibrillin 1 | -0.0702255 |
| GLIS3 | GLIS family zinc finger 3 | -0.0699276 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0695939 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0658364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0629286 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0614007 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0603422 |
| VCAN | versican | -0.0602987 |
| CALD1 | caldesmon 1 | -0.0558428 |
| TPM4 | tropomyosin 4 | -0.0541682 |
| DST | dystonin | -0.0541681 |
| ACTG1 | actin gamma 1 | -0.0491931 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0487916 |
| NAV1 | neuron navigator 1 | -0.0473194 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0463443 |
| CNTN5 | contactin 5 | -0.0452827 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0446955 |
| IL6ST | interleukin 6 signal transducer | -0.0446002 |
| COL1A2 | collagen, type I, alpha 2 | -0.0444447 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0439874 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.043478 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0431784 |
| MAP1B | microtubule-associated protein 1B | -0.0425901 |
| LOX | lysyl oxidase | -0.0414422 |
| INHBA | inhibin, beta A | -0.0409511 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0385072 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0379272 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0375492 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0375151 |
| SMYD3 | SET and MYND domain containing 3 | -0.0369543 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0363445 |
| EGR1 | early growth response 1 | -0.0363032 |
| ATXN1 | ataxin 1 | -0.0358514 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0353186 |
| VCL | vinculin | -0.0350955 |
| ENO1 | enolase 1, (alpha) | -0.034897 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0345898 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0343327 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0337306 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0335876 |
| FOXP1 | forkhead box P1 | -0.0335041 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0327959 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0324493 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0323683 |
| IER3 | immediate early response 3 | -0.0321991 |
| NRP1 | neuropilin 1 | -0.0320218 |
| STC1 | stanniocalcin 1 | -0.0315196 |
| TENM3 | teneurin transmembrane protein 3 | -0.031302 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0311351 |
| OSMR | oncostatin M receptor | -0.0311082 |
| CLIC4 | chloride intracellular channel 4 | -0.0306461 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0305274 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0295035 |
| PRELID2 | PRELI domain containing 2 | -0.0294411 |
| EBF1 | early B-cell factor 1 | -0.0293831 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0293377 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0292315 |
| NREP | neuronal regeneration related protein | -0.028999 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0289251 |
| MT2A | metallothionein 2A | -0.0288703 |
| FRMD4A | FERM domain containing 4A | -0.0285117 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0283365 |
| LOXL2 | lysyl oxidase-like 2 | -0.0276438 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0274737 |
| TPM1 | tropomyosin 1 (alpha) | -0.0274298 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0274159 |
| ATM | ATM serine/threonine kinase | -0.026743 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0265534 |
| HMCN1 | hemicentin 1 | -0.0262534 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0262238 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0258111 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0251475 |
| NAV3 | neuron navigator 3 | -0.0250017 |
| COL5A1 | collagen, type V, alpha 1 | -0.024583 |
| EGFR | epidermal growth factor receptor | -0.0245739 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0245338 |
| COL6A1 | collagen, type VI, alpha 1 | -0.024488 |
| PALLD | palladin, cytoskeletal associated protein | -0.0244497 |
| CPQ | carboxypeptidase Q | -0.0239113 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0237295 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0235386 |
| FTL | ferritin, light polypeptide | -0.0233586 |
| CALU | calumenin | -0.0226378 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0226064 |
| PRSS23 | protease, serine, 23 | -0.0224601 |
