| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.18639 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.084521 |
| GOLGA4 | golgin A4 | 0.0750158 |
| CLU | clusterin | 0.074636 |
| ITGA6 | integrin, alpha 6 | 0.0647913 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0644238 |
| MSN | moesin | 0.0620836 |
| NDRG1 | N-myc downstream regulated 1 | 0.0597243 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.055246 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0542244 |
| POTEF | POTE ankyrin domain family, member F | 0.05158 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0498706 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0492819 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0471867 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0454383 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0429325 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0423832 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0421767 |
| SMAD3 | SMAD family member 3 | 0.0416252 |
| BCL2L1 | BCL2-like 1 | 0.0416003 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0413098 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0408893 |
| ANLN | anillin, actin binding protein | 0.0404729 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0401949 |
| SPAG9 | sperm associated antigen 9 | 0.0385498 |
| OGA | O-GlcNAcase | 0.0377563 |
| FOXO1 | forkhead box O1 | 0.0375888 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0368779 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0367894 |
| TGM2 | transglutaminase 2 | 0.0362252 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0355209 |
| KRT17 | keratin 17, type I | 0.0338341 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0334039 |
| GLYAT | glycine-N-acyltransferase | 0.0323941 |
| FOSL1 | FOS-like antigen 1 | 0.0323593 |
| EZR | ezrin | 0.0318781 |
| RNF19B | ring finger protein 19B | 0.0316578 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0313869 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0311361 |
| COPA | coatomer protein complex, subunit alpha | 0.0311078 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0310728 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0309182 |
| TPM3 | tropomyosin 3 | 0.0308699 |
| SRP54 | signal recognition particle 54kDa | 0.0302503 |
| CUL4B | cullin 4B | 0.0301775 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0301566 |
| SQLE | squalene epoxidase | 0.0300977 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0297713 |
| MEF2A | myocyte enhancer factor 2A | 0.0297567 |
| ENO1 | enolase 1, (alpha) | 0.0294111 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0290345 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0290026 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0288917 |
| INSIG2 | insulin induced gene 2 | 0.0283401 |
| SERINC3 | serine incorporator 3 | 0.0280314 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0277932 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0277555 |
| EFHD2 | EF-hand domain family, member D2 | 0.0277178 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0275611 |
| USP33 | ubiquitin specific peptidase 33 | 0.0274876 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0273521 |
| CD99 | CD99 molecule | 0.0273255 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0271883 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0271057 |
| NBAS | neuroblastoma amplified sequence | 0.0267414 |
| COG5 | component of oligomeric golgi complex 5 | 0.0266829 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0264441 |
| DIAPH3 | diaphanous-related formin 3 | 0.0263645 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0261834 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0256578 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0256502 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0255229 |
| ARRDC3 | arrestin domain containing 3 | 0.0252967 |
| YBX1 | Y box binding protein 1 | 0.0252883 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0250093 |
| PTMA | prothymosin, alpha | 0.024934 |
| NCOA3 | nuclear receptor coactivator 3 | 0.024233 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0242098 |
| GATA6 | GATA binding protein 6 | 0.0242031 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0242031 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0238688 |
| MCL1 | myeloid cell leukemia 1 | 0.0238118 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0237885 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0237479 |
| PCDH1 | protocadherin 1 | 0.0236866 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0236661 |
| MYO10 | myosin X | 0.0236241 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0235452 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0234475 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0231396 |
| PKM | pyruvate kinase, muscle | 0.0231063 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0229932 |
| EMP1 | epithelial membrane protein 1 | 0.0229845 |
| TAGLN2 | transgelin 2 | 0.0226086 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0225441 |
| ANXA11 | annexin A11 | 0.0223377 |
| MYOF | myoferlin | 0.0222675 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0221747 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0220864 |
| KRT6A | keratin 6A, type II | 0.0219279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.363001 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.257904 |
| MTSS1 | metastasis suppressor 1 | -0.149487 |
| PDLIM5 | PDZ and LIM domain 5 | -0.1177 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.116933 |
| INTS6 | integrator complex subunit 6 | -0.115577 |
| LMO7 | LIM domain 7 | -0.104673 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0915892 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0871977 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0819532 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.078313 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0765184 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0747329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0691998 |
| SULF2 | sulfatase 2 | -0.0689425 |
| PALLD | palladin, cytoskeletal associated protein | -0.0635094 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0628621 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0590091 |
| HMGA2 | high mobility group AT-hook 2 | -0.0555184 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0540817 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0539246 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0530174 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0520143 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0512623 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0512244 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0508201 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0507065 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0501038 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0499929 |
| HDAC9 | histone deacetylase 9 | -0.0488352 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.048422 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0461928 |
| SMYD3 | SET and MYND domain containing 3 | -0.0458447 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0444945 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.043877 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0423687 |
| VCL | vinculin | -0.0420406 |
| MTAP | methylthioadenosine phosphorylase | -0.0418383 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0417144 |
| ASPH | aspartate beta-hydroxylase | -0.0415133 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.04147 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0405452 |
| RPL34 | ribosomal protein L34 | -0.0404187 |
| DST | dystonin | -0.0402228 |
| EFNA5 | ephrin-A5 | -0.0398674 |
| RIGI | RNA sensor RIG-I | -0.0398057 |
| FOXP1 | forkhead box P1 | -0.0396968 |
| RAD51B | RAD51 paralog B | -0.0392482 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0382366 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0380272 |
| PRSS23 | protease, serine, 23 | -0.0377985 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0370206 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0368497 |
| SP100 | SP100 nuclear antigen | -0.036123 |
| RPS8 | ribosomal protein S8 | -0.0359567 |
| TMSB10 | thymosin beta 10 | -0.035788 |
| STC1 | stanniocalcin 1 | -0.0352263 |
| MECOM | MDS1 and EVI1 complex locus | -0.0350329 |
| RCOR1 | REST corepressor 1 | -0.0343592 |
| CDK6 | cyclin-dependent kinase 6 | -0.03389 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.033727 |
| RPS12 | ribosomal protein S12 | -0.032989 |
| GNAS | GNAS complex locus | -0.0329681 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0329053 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0327994 |
| EXOC4 | exocyst complex component 4 | -0.0319226 |
| RASAL2 | RAS protein activator like 2 | -0.0313672 |
| DOK5 | docking protein 5 | -0.0312864 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0311184 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.031071 |
| S100A10 | S100 calcium binding protein A10 | -0.0287758 |
| PCDH9 | protocadherin 9 | -0.0287089 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0285827 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0284559 |
| HLA-B | major histocompatibility complex, class I, B | -0.0283909 |
| DGKH | diacylglycerol kinase, eta | -0.0280496 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0279245 |
| IFI44L | interferon-induced protein 44-like | -0.0277688 |
| RPS24 | ribosomal protein S24 | -0.0276437 |
| CDK13 | cyclin-dependent kinase 13 | -0.0275546 |
| MT2A | metallothionein 2A | -0.0275116 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.027353 |
| JMJD1C | jumonji domain containing 1C | -0.0273509 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0272839 |
| RAI14 | retinoic acid induced 14 | -0.027238 |
| RPL37 | ribosomal protein L37 | -0.0271055 |
| SQSTM1 | sequestosome 1 | -0.0269419 |
| RPL26 | ribosomal protein L26 | -0.0266618 |
| AOPEP | aminopeptidase O (putative) | -0.0265632 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.026517 |
| DENND1A | DENN/MADD domain containing 1A | -0.026291 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.026286 |
| UTRN | utrophin | -0.0261341 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.025652 |
| RNF217 | ring finger protein 217 | -0.0255403 |
| CLIC4 | chloride intracellular channel 4 | -0.0248917 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0247986 |
| RPL35A | ribosomal protein L35a | -0.0247713 |
| OXR1 | oxidation resistance 1 | -0.0247335 |
| RPS6 | ribosomal protein S6 | -0.0246593 |
