| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pioglitazone_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA6 | integrin, alpha 6 | 0.177289 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.174317 |
| TXNIP | thioredoxin interacting protein | 0.131623 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.119983 |
| FAT1 | FAT atypical cadherin 1 | 0.116611 |
| DSPP | dentin sialophosphoprotein | 0.106517 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.106021 |
| AREG | amphiregulin | 0.0995468 |
| EZR | ezrin | 0.0973072 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0965117 |
| LDHA | lactate dehydrogenase A | 0.0945196 |
| FLNB | filamin B, beta | 0.0926864 |
| LMO7 | LIM domain 7 | 0.0894894 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0793986 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0755832 |
| KRT18 | keratin 18, type I | 0.0728199 |
| ENO1 | enolase 1, (alpha) | 0.0722541 |
| CANX | calnexin | 0.0659862 |
| ASPH | aspartate beta-hydroxylase | 0.0654941 |
| NDRG1 | N-myc downstream regulated 1 | 0.064627 |
| EMP1 | epithelial membrane protein 1 | 0.0636905 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0627035 |
| VEGFA | vascular endothelial growth factor A | 0.0604958 |
| FAM13A | family with sequence similarity 13, member A | 0.0538419 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0533217 |
| ANXA1 | annexin A1 | 0.0532192 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0526878 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0520071 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0514299 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0512581 |
| EHF | ets homologous factor | 0.0480463 |
| ANXA2 | annexin A2 | 0.047326 |
| KRT19 | keratin 19, type I | 0.0463375 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0454326 |
| MUC17 | mucin 17, cell surface associated | 0.0453552 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.044569 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0439601 |
| RPL11 | ribosomal protein L11 | 0.0439565 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0437242 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0435978 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0432161 |
| AHNAK | AHNAK nucleoprotein | 0.0431547 |
| MED13L | mediator complex subunit 13-like | 0.0428834 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0421677 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0421426 |
| PGK1 | phosphoglycerate kinase 1 | 0.0420969 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0417739 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0417297 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0408196 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0401892 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0399118 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0397269 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.039708 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0394459 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.039346 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.039286 |
| MYO1E | myosin IE | 0.038845 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0374851 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0372946 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0371352 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0369506 |
| MED13 | mediator complex subunit 13 | 0.0368222 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.036751 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0365772 |
| SLK | STE20-like kinase | 0.036162 |
| PCBP2 | poly(rC) binding protein 2 | 0.036062 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0360102 |
| CALB1 | calbindin 1, 28kDa | 0.0358817 |
| CALR | calreticulin | 0.0357774 |
| RCOR1 | REST corepressor 1 | 0.0352739 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0351594 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0347935 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.034659 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0344626 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0342362 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0335951 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0333514 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0332863 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0331499 |
| ANXA11 | annexin A11 | 0.0329982 |
| EREG | epiregulin | 0.0328037 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0324902 |
| TPM3 | tropomyosin 3 | 0.0324785 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0323888 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0323569 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0323514 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0321855 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0321658 |
| PRELID2 | PRELI domain containing 2 | 0.0319945 |
| MLEC | malectin | 0.0319765 |
| CCNY | cyclin Y | 0.0317978 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0313437 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0313205 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.031302 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0311674 |
| YTHDC1 | YTH domain containing 1 | 0.0309517 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0307854 |
| APP | amyloid beta (A4) precursor protein | 0.030569 |
| FBXO11 | F-box protein 11 | 0.0305626 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0298959 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.135705 |
| NPSR1 | neuropeptide S receptor 1 | -0.090285 |
| TNS4 | tensin 4 | -0.0857206 |
| GPHN | gephyrin | -0.0747881 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0746411 |
| VCL | vinculin | -0.0684193 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0649584 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0556081 |
| RNF43 | ring finger protein 43 | -0.0455391 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0443944 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0438204 |
| HMGB1 | high mobility group box 1 | -0.0433662 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0432926 |
| H1-0 | H1.0 linker histone | -0.0423648 |
| AGR2 | anterior gradient 2 | -0.0403541 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0402903 |
| PRSS3 | protease, serine, 3 | -0.0400248 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.03925 |
| RPS24 | ribosomal protein S24 | -0.0367224 |
| ONECUT3 | one cut homeobox 3 | -0.0365032 |
| RPLP1 | ribosomal protein, large, P1 | -0.0348808 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0339939 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0324099 |
| FOXP1 | forkhead box P1 | -0.0311955 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0299886 |
| RESF1 | retroelement silencing factor 1 | -0.0295596 |
| ACTG1 | actin gamma 1 | -0.0275322 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0266404 |
| CLTC | clathrin, heavy chain (Hc) | -0.0265885 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.026508 |
| FHIT | fragile histidine triad | -0.0264522 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0264422 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0261212 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0249451 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0247943 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0243436 |
| NRXN3 | neurexin 3 | -0.0236106 |
| RPL35A | ribosomal protein L35a | -0.0234991 |
| MECOM | MDS1 and EVI1 complex locus | -0.0229799 |
| PCNX2 | pecanex 2 | -0.022796 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0224596 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0219305 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0217679 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0217242 |
| TFRC | transferrin receptor | -0.0215073 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0214752 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.021313 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0207194 |
| PKP2 | plakophilin 2 | -0.0207078 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0204843 |
| TMSB10 | thymosin beta 10 | -0.0204428 |
| KAZN | kazrin, periplakin interacting protein | -0.020086 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0199817 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0199531 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0198656 |
| MAP4 | microtubule-associated protein 4 | -0.0198091 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0197849 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0196701 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0196239 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0193675 |
| PALLD | palladin, cytoskeletal associated protein | -0.0193635 |
| NFIA | nuclear factor I/A | -0.0193558 |
| RPL38 | ribosomal protein L38 | -0.0192086 |
| MYO9A | myosin IXA | -0.019188 |
| SEC24D | SEC24 family member D | -0.0191864 |
| TPM4 | tropomyosin 4 | -0.019152 |
| COMMD10 | COMM domain containing 10 | -0.0189827 |
| CCND1 | cyclin D1 | -0.0189688 |
| ENOSF1 | enolase superfamily member 1 | -0.0188593 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0187482 |
| FOXP2 | forkhead box P2 | -0.0187023 |
| SMYD3 | SET and MYND domain containing 3 | -0.0186918 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0185012 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0182833 |
| MTAP | methylthioadenosine phosphorylase | -0.0182695 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0180701 |
| LRRK1 | leucine-rich repeat kinase 1 | -0.0180649 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | -0.0179825 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0179204 |
| IER3 | immediate early response 3 | -0.0178118 |
| RPL6 | ribosomal protein L6 | -0.0178115 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0177613 |
| CUL1 | cullin 1 | -0.017756 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0176567 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0175272 |
| RPL9 | ribosomal protein L9 | -0.0173809 |
| RBM25 | RNA binding motif protein 25 | -0.01733 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0173242 |
| KIAA1217 | KIAA1217 | -0.0172016 |
| TPM1 | tropomyosin 1 (alpha) | -0.0170821 |
| EGR1 | early growth response 1 | -0.0170523 |
| RFX7 | regulatory factor X, 7 | -0.0169719 |
| RTN3 | reticulon 3 | -0.0166659 |
| RUBCNL | rubicon like autophagy enhancer | -0.0166603 |
| MALT1 | MALT1 paracaspase | -0.0165622 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0165616 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0165109 |
| HM13 | histocompatibility (minor) 13 | -0.0162453 |
| PYGB | phosphorylase, glycogen; brain | -0.0162108 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0161551 |
