| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.126241 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.110469 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.10366 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0942317 |
| CANX | calnexin | 0.0854567 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0844468 |
| TXNRD1 | thioredoxin reductase 1 | 0.0781266 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.076062 |
| FMNL2 | formin-like 2 | 0.0676943 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0649524 |
| EZR | ezrin | 0.0638184 |
| HDAC9 | histone deacetylase 9 | 0.0636359 |
| RAI1 | retinoic acid induced 1 | 0.063113 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.059676 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0594815 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0565903 |
| CALR | calreticulin | 0.0547396 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0530356 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0515327 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0514635 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0509773 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0498683 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0481406 |
| SQSTM1 | sequestosome 1 | 0.0473993 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.047387 |
| FNIP1 | folliculin interacting protein 1 | 0.0467119 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0454003 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0443338 |
| LOXL2 | lysyl oxidase-like 2 | 0.0442486 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0436495 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0433917 |
| RUNX1 | runt-related transcription factor 1 | 0.0432357 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0430217 |
| YEATS2 | YEATS domain containing 2 | 0.0423258 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0418822 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0416737 |
| RAD51B | RAD51 paralog B | 0.0415343 |
| ENO1 | enolase 1, (alpha) | 0.0414368 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0411721 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411691 |
| DENND1A | DENN/MADD domain containing 1A | 0.0398811 |
| SMAD3 | SMAD family member 3 | 0.0391282 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0387346 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0375579 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0375251 |
| ARRDC3 | arrestin domain containing 3 | 0.0374598 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0369747 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0365989 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0362473 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0361146 |
| MCL1 | myeloid cell leukemia 1 | 0.0359704 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0357471 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0354451 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0354068 |
| CLTC | clathrin, heavy chain (Hc) | 0.0343806 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0343336 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0338933 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0330018 |
| GLG1 | golgi glycoprotein 1 | 0.0327854 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0323128 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0322635 |
| MYOF | myoferlin | 0.0320601 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0318745 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0317939 |
| EXOC4 | exocyst complex component 4 | 0.0312717 |
| PLK2 | polo-like kinase 2 | 0.0309634 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0308801 |
| APP | amyloid beta (A4) precursor protein | 0.0308383 |
| UPP1 | uridine phosphorylase 1 | 0.0306791 |
| SBF2 | SET binding factor 2 | 0.0306369 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0301836 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0301098 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0298888 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0298819 |
| NAV2 | neuron navigator 2 | 0.0298358 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297895 |
| SMYD3 | SET and MYND domain containing 3 | 0.0297722 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0296354 |
| XPO1 | exportin 1 | 0.0295631 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.02937 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0293431 |
| PDE8A | phosphodiesterase 8A | 0.0292753 |
| VCL | vinculin | 0.0290347 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0287452 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.028663 |
| PTK2 | protein tyrosine kinase 2 | 0.0284868 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0283211 |
| USP34 | ubiquitin specific peptidase 34 | 0.0283152 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0281113 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0280006 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0279978 |
| PGK1 | phosphoglycerate kinase 1 | 0.0279859 |
| ZNF292 | zinc finger protein 292 | 0.027749 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0276487 |
| IGF1R | insulin-like growth factor 1 receptor | 0.02741 |
| CCDC47 | coiled-coil domain containing 47 | 0.0273682 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0273387 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0273139 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0269179 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269119 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.201912 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0781561 |
| MT2A | metallothionein 2A | -0.0759233 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0626193 |
| RPS6 | ribosomal protein S6 | -0.0624866 |
| RPL35A | ribosomal protein L35a | -0.0549138 |
| ACTG1 | actin gamma 1 | -0.054724 |
| POTEF | POTE ankyrin domain family, member F | -0.0503868 |
| TMSB10 | thymosin beta 10 | -0.045493 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0423426 |
| RAB27B | RAB27B, member RAS oncogene family | -0.036157 |
| MT1X | metallothionein 1X | -0.0350943 |
| RPS24 | ribosomal protein S24 | -0.0346367 |
| PTMA | prothymosin, alpha | -0.0344476 |
| RPL37 | ribosomal protein L37 | -0.0328336 |
| TMSB4X | thymosin beta 4, X-linked | -0.0324226 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0324014 |
| RPS8 | ribosomal protein S8 | -0.0314226 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0306993 |
| RPL9 | ribosomal protein L9 | -0.0306093 |
| RPS19 | ribosomal protein S19 | -0.0300997 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0280247 |
| HLA-B | major histocompatibility complex, class I, B | -0.0265452 |
| RPLP1 | ribosomal protein, large, P1 | -0.0261993 |
| PLIN2 | perilipin 2 | -0.0258128 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0257649 |
| KLF6 | Kruppel-like factor 6 | -0.0256336 |
| TP63 | tumor protein p63 | -0.0256331 |
| RPL26 | ribosomal protein L26 | -0.0254925 |
| RPS12 | ribosomal protein S12 | -0.0250285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0248321 |
| RPL19 | ribosomal protein L19 | -0.0244536 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0241541 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0228728 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227059 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0225712 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0224916 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0214021 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.021284 |
| RPS25 | ribosomal protein S25 | -0.0212806 |
| RPS23 | ribosomal protein S23 | -0.020959 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0209286 |
| RPL36 | ribosomal protein L36 | -0.0209275 |
| RPL37A | ribosomal protein L37a | -0.0207285 |
| H1-0 | H1.0 linker histone | -0.0199733 |
| CADM2 | cell adhesion molecule 2 | -0.0198834 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0196452 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0194796 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0193998 |
| HMGA1 | high mobility group AT-hook 1 | -0.019363 |
| DST | dystonin | -0.0189754 |
| HMGB1 | high mobility group box 1 | -0.0187312 |
| TAPBP | TAP binding protein (tapasin) | -0.0185805 |
| WDR43 | WD repeat domain 43 | -0.0185075 |
| TLK1 | tousled-like kinase 1 | -0.0184153 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0182742 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0179729 |
| CD44 | CD44 molecule (Indian blood group) | -0.0179647 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0176973 |
| RGS4 | regulator of G-protein signaling 4 | -0.0173254 |
| RPS11 | ribosomal protein S11 | -0.0173021 |
| RPL34 | ribosomal protein L34 | -0.0171825 |
| URI1 | URI1, prefoldin-like chaperone | -0.0171121 |
| NPR2 | natriuretic peptide receptor 2 | -0.0169943 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0169878 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0168527 |
| RPS28 | ribosomal protein S28 | -0.0164378 |
| NEMF | nuclear export mediator factor | -0.016268 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.016253 |
| HLA-A | major histocompatibility complex, class I, A | -0.0161863 |
| RPS4X | ribosomal protein S4, X-linked | -0.0161526 |
| RPS14 | ribosomal protein S14 | -0.0157366 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0157137 |
| RPS27A | ribosomal protein S27a | -0.0155691 |
| RPL27 | ribosomal protein L27 | -0.0155168 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0154181 |
| RPL36A | ribosomal protein L36a | -0.0154067 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0152911 |
| RPL23 | ribosomal protein L23 | -0.0152572 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0152106 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0151386 |
| COL5A2 | collagen, type V, alpha 2 | -0.0150816 |
| RPL12 | ribosomal protein L12 | -0.0150745 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0149874 |
| NOP58 | NOP58 ribonucleoprotein | -0.0149655 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.0149653 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0147484 |
| RPS21 | ribosomal protein S21 | -0.0145603 |
| DEK | DEK proto-oncogene | -0.0145511 |
| RPL35 | ribosomal protein L35 | -0.0145294 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0144916 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0144099 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0143268 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0143228 |
| BRD4 | bromodomain containing 4 | -0.0141599 |
| RPL31 | ribosomal protein L31 | -0.0141239 |
| RBM25 | RNA binding motif protein 25 | -0.0139494 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0139073 |
| YBX1 | Y box binding protein 1 | -0.0138549 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -0.0138451 |
