| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.118886 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0919238 |
| FAM13A | family with sequence similarity 13, member A | 0.0729303 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0723801 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0711473 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0701479 |
| SPAG9 | sperm associated antigen 9 | 0.0597314 |
| CANX | calnexin | 0.0588042 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0572794 |
| ARRDC3 | arrestin domain containing 3 | 0.0507457 |
| OGA | O-GlcNAcase | 0.0497031 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0463203 |
| NGLY1 | N-glycanase 1 | 0.0463077 |
| CES1 | carboxylesterase 1 | 0.0441227 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0431265 |
| LAMB3 | laminin, beta 3 | 0.0429613 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.042329 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0414277 |
| HDLBP | high density lipoprotein binding protein | 0.041012 |
| TOP1 | topoisomerase (DNA) I | 0.0396175 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0386764 |
| MKI67 | marker of proliferation Ki-67 | 0.0378917 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0356035 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0353191 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0349971 |
| WDR45B | WD repeat domain 45B | 0.0345561 |
| AHNAK | AHNAK nucleoprotein | 0.0344506 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0341397 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0340379 |
| ANO6 | anoctamin 6 | 0.0339166 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0333587 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0328233 |
| JMJD1C | jumonji domain containing 1C | 0.0327496 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.032037 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0316848 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0315994 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0314569 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0314493 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0310543 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0310464 |
| DSPP | dentin sialophosphoprotein | 0.0307776 |
| TPD52 | tumor protein D52 | 0.0304146 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0303796 |
| PLEC | plectin | 0.0303225 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0299224 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0295851 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294672 |
| TMEM165 | transmembrane protein 165 | 0.0294393 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.029346 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0289776 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0287848 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0287382 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.028685 |
| YTHDC1 | YTH domain containing 1 | 0.0286164 |
| HYOU1 | hypoxia up-regulated 1 | 0.0284129 |
| PRRC2C | proline-rich coiled-coil 2C | 0.028171 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0281574 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0280256 |
| FNIP1 | folliculin interacting protein 1 | 0.028013 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0279789 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268387 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0265871 |
| NDRG1 | N-myc downstream regulated 1 | 0.0261306 |
| SRP54 | signal recognition particle 54kDa | 0.0260084 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.026008 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0260026 |
| HELZ | helicase with zinc finger | 0.0255601 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0254522 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0252926 |
| SQSTM1 | sequestosome 1 | 0.0251217 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0248512 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0247566 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0245985 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0242862 |
| PGK1 | phosphoglycerate kinase 1 | 0.0241651 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0240154 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0239839 |
| RBM39 | RNA binding motif protein 39 | 0.0235552 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0235248 |
| SUCO | SUN domain containing ossification factor | 0.0235084 |
| RNF169 | ring finger protein 169 | 0.0234188 |
| LAMC2 | laminin, gamma 2 | 0.0234041 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.023323 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0232074 |
| UVRAG | UV radiation resistance associated | 0.0231587 |
| SMAD3 | SMAD family member 3 | 0.0226648 |
| NPTN | neuroplastin | 0.0225543 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.022208 |
| PTMA | prothymosin, alpha | 0.0221956 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0221867 |
| ABLIM1 | actin binding LIM protein 1 | 0.0221467 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0219328 |
| ATP13A3 | ATPase type 13A3 | 0.0218454 |
| PDE8A | phosphodiesterase 8A | 0.0217498 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0216529 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.021222 |
| ATG14 | autophagy related 14 | 0.0209829 |
| RNF145 | ring finger protein 145 | 0.0207236 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0206443 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0206125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155285 |
| EGFR | epidermal growth factor receptor | -0.126428 |
| TMSB10 | thymosin beta 10 | -0.119072 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0876067 |
| EGR1 | early growth response 1 | -0.0820527 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0727065 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0700967 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0686799 |
| ACTG1 | actin gamma 1 | -0.065835 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0619303 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0607966 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0599523 |
| ASPH | aspartate beta-hydroxylase | -0.0553173 |
| CST3 | cystatin C | -0.0474686 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0458362 |
| OSMR | oncostatin M receptor | -0.044725 |
| PKM | pyruvate kinase, muscle | -0.0436911 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0410377 |
| SCEL | sciellin | -0.0410293 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0399216 |
| EFNA5 | ephrin-A5 | -0.0379748 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0363501 |
| POTEF | POTE ankyrin domain family, member F | -0.0350262 |
| NABP1 | nucleic acid binding protein 1 | -0.0338789 |
| LAMA4 | laminin, alpha 4 | -0.0333711 |
| S100A10 | S100 calcium binding protein A10 | -0.033073 |
| AREG | amphiregulin | -0.0326298 |
| KRT7 | keratin 7, type II | -0.0325169 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0318408 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0314543 |
| GRAMD1B | GRAM domain containing 1B | -0.031185 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0310685 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0309941 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0307352 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0297217 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029155 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0291523 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0290755 |
| CAV2 | caveolin 2 | -0.0278695 |
| FOXP1 | forkhead box P1 | -0.0273922 |
| CCND1 | cyclin D1 | -0.0272429 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0270163 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0258554 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0256386 |
| MT2A | metallothionein 2A | -0.0249684 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0248837 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0244009 |
| S100A11 | S100 calcium binding protein A11 | -0.0240616 |
| SLC38A2 | solute carrier family 38, member 2 | -0.023267 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0232616 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0231724 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.022948 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0225958 |
| KRT8 | keratin 8, type II | -0.0218166 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0217291 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0215751 |
| VCL | vinculin | -0.0212624 |
| CUX1 | cut-like homeobox 1 | -0.0212316 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0211411 |
| TJP1 | tight junction protein 1 | -0.020681 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0203324 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0201095 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0200695 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0195934 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0195305 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0193999 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0190133 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0190029 |
| TPM4 | tropomyosin 4 | -0.0189531 |
| NTN4 | netrin 4 | -0.0187624 |
| TXNRD1 | thioredoxin reductase 1 | -0.018452 |
| RNF213 | ring finger protein 213 | -0.0184463 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0184431 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0181637 |
| MT1X | metallothionein 1X | -0.0181218 |
| MYO1D | myosin ID | -0.0175244 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0174779 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0174696 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0174123 |
| TNS3 | tensin 3 | -0.0171077 |
| PFN1 | profilin 1 | -0.0168389 |
| RIN2 | Ras and Rab interactor 2 | -0.0165968 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0165752 |
| IFI44L | interferon-induced protein 44-like | -0.0164741 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0159821 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.015946 |
| PCED1B | PC-esterase domain containing 1B | -0.0158432 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0157916 |
| KRT19 | keratin 19, type I | -0.0156406 |
| SUMF1 | sulfatase modifying factor 1 | -0.0156255 |
| HMGA1 | high mobility group AT-hook 1 | -0.0155815 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0154187 |
| MYO1E | myosin IE | -0.0152493 |
| CMIP | c-Maf inducing protein | -0.0151942 |
| RAD51B | RAD51 paralog B | -0.0151426 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0151244 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0148479 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0147899 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0145707 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0144671 |
