| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0982316 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0964399 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0917451 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0898322 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0853184 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0793036 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.070029 |
| PTK2 | protein tyrosine kinase 2 | 0.0674822 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0624608 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0573251 |
| FGB | fibrinogen beta chain | 0.0563054 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0558065 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553761 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.054398 |
| TPM3 | tropomyosin 3 | 0.0541472 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.052586 |
| MCL1 | myeloid cell leukemia 1 | 0.0484064 |
| FAM168A | family with sequence similarity 168, member A | 0.0483436 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0480729 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0477222 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0474662 |
| CALR | calreticulin | 0.0464595 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0462322 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0460906 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0454 |
| ERBIN | erbb2 interacting protein | 0.0450062 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0448547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0447586 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0442151 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0440722 |
| FMNL2 | formin-like 2 | 0.0439245 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0422628 |
| APP | amyloid beta (A4) precursor protein | 0.0419086 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.041295 |
| RTN4 | reticulon 4 | 0.0412396 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0404497 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0401888 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0399652 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0391195 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0387988 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0384604 |
| PCBP2 | poly(rC) binding protein 2 | 0.0378067 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0377903 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0368947 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.036207 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0356824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0345813 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0345527 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0345231 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0344257 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0344027 |
| UBAP2L | ubiquitin associated protein 2-like | 0.034066 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0339467 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0337244 |
| FLNB | filamin B, beta | 0.0332706 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0330361 |
| KIF5B | kinesin family member 5B | 0.0324437 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0323644 |
| TPD52 | tumor protein D52 | 0.0321066 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0318594 |
| WDR43 | WD repeat domain 43 | 0.0317343 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0316649 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0314721 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302049 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0299899 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0299035 |
| B2M | beta-2-microglobulin | 0.0295567 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0289595 |
| USP36 | ubiquitin specific peptidase 36 | 0.0284573 |
| CALU | calumenin | 0.0284253 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0283168 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0282502 |
| FNBP1L | formin binding protein 1-like | 0.0280405 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0278102 |
| MSN | moesin | 0.0270022 |
| PNN | pinin, desmosome associated protein | 0.0269565 |
| GANAB | glucosidase, alpha; neutral AB | 0.0268633 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0265958 |
| HELZ | helicase with zinc finger | 0.0262764 |
| YTHDC1 | YTH domain containing 1 | 0.0261067 |
| ANXA2 | annexin A2 | 0.0258547 |
| TAGLN2 | transgelin 2 | 0.0256086 |
| COPA | coatomer protein complex, subunit alpha | 0.0255631 |
| CANX | calnexin | 0.0254775 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0253233 |
| CLU | clusterin | 0.0253222 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0252984 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0251945 |
| JAK1 | Janus kinase 1 | 0.0251721 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0251465 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0249226 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0248339 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0246276 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0245705 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0245514 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.024462 |
| MYOF | myoferlin | 0.0243275 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0242231 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0240875 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0239659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.239438 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.237927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142795 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.135246 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.126678 |
| FTL | ferritin, light polypeptide | -0.116227 |
| TMSB10 | thymosin beta 10 | -0.107714 |
| TXNRD1 | thioredoxin reductase 1 | -0.0814793 |
| ACTG1 | actin gamma 1 | -0.0727219 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0640506 |
| IER3 | immediate early response 3 | -0.0567379 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0558886 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0531591 |
| GRAMD1B | GRAM domain containing 1B | -0.052277 |
| RPLP1 | ribosomal protein, large, P1 | -0.044571 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0425421 |
| NRG1 | neuregulin 1 | -0.0404829 |
| BICC1 | BicC family RNA binding protein 1 | -0.0400965 |
| IGF2 | insulin-like growth factor 2 | -0.0399484 |
| RPL35A | ribosomal protein L35a | -0.0374878 |
| RPS8 | ribosomal protein S8 | -0.0371362 |
| S100A10 | S100 calcium binding protein A10 | -0.0369906 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0364551 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0353705 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0347026 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0337638 |
| EFNA5 | ephrin-A5 | -0.0334844 |
| RPS19 | ribosomal protein S19 | -0.0334418 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0331706 |
| HMGB1 | high mobility group box 1 | -0.0316789 |
| RPS21 | ribosomal protein S21 | -0.0311049 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.030364 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0300826 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0297601 |
| RPS23 | ribosomal protein S23 | -0.0293762 |
| RPL19 | ribosomal protein L19 | -0.0292007 |
| WWOX | WW domain containing oxidoreductase | -0.0287649 |
| OSMR | oncostatin M receptor | -0.0276835 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0273969 |
| RPL34 | ribosomal protein L34 | -0.0271245 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0265943 |
| S100A6 | S100 calcium binding protein A6 | -0.0262247 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.025627 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0251119 |
| RPS25 | ribosomal protein S25 | -0.0244914 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0241705 |
| RPS6 | ribosomal protein S6 | -0.0237378 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0229473 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.022942 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0229358 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0225511 |
| KYNU | kynureninase | -0.0219331 |
| FHIT | fragile histidine triad | -0.0217503 |
| RSPO3 | R-spondin 3 | -0.0217216 |
| RPL12 | ribosomal protein L12 | -0.0215982 |
| RPS20 | ribosomal protein S20 | -0.0215149 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0213922 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0209957 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0209664 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0207932 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0207173 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0202419 |
| GNAS | GNAS complex locus | -0.0200445 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0191634 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0188319 |
| RPL36 | ribosomal protein L36 | -0.0182864 |
| RPL38 | ribosomal protein L38 | -0.0179739 |
| RPL27 | ribosomal protein L27 | -0.0178831 |
| RPLP0 | ribosomal protein, large, P0 | -0.0176511 |
| RPL9 | ribosomal protein L9 | -0.0175894 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0175564 |
| NEGR1 | neuronal growth regulator 1 | -0.0175347 |
| RPS11 | ribosomal protein S11 | -0.0173766 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0172392 |
| UBB | ubiquitin B | -0.0172372 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0171672 |
| EGR1 | early growth response 1 | -0.0169142 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0168467 |
| RPS16 | ribosomal protein S16 | -0.0167451 |
| TUBB | tubulin, beta class I | -0.0166373 |
| RPS5 | ribosomal protein S5 | -0.0166002 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0164718 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0163715 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0163423 |
| TKT | transketolase | -0.0160921 |
| SSH1 | slingshot protein phosphatase 1 | -0.0159855 |
| NAV3 | neuron navigator 3 | -0.0159304 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0157112 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0157077 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0156306 |
| STC1 | stanniocalcin 1 | -0.0155069 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0154388 |
| RPL30 | ribosomal protein L30 | -0.0153377 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.0153033 |
| TUBA1B | tubulin, alpha 1b | -0.0152385 |
| MT1X | metallothionein 1X | -0.0152215 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0152165 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0151066 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0150684 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0147724 |
