| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.13542 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.105112 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.104682 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0984778 |
| LDHA | lactate dehydrogenase A | 0.0944609 |
| KRT17 | keratin 17, type I | 0.0867696 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0815514 |
| EFNA5 | ephrin-A5 | 0.0776989 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0768415 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0768168 |
| SMYD3 | SET and MYND domain containing 3 | 0.0764702 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0742907 |
| HELZ | helicase with zinc finger | 0.0727953 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0724085 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0724018 |
| VMP1 | vacuole membrane protein 1 | 0.0716468 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0689209 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0671277 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0652959 |
| PTMA | prothymosin, alpha | 0.0626954 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0610476 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0604729 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0603481 |
| FTL | ferritin, light polypeptide | 0.0595704 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0587511 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.058196 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0564161 |
| EZR | ezrin | 0.0545349 |
| TXNIP | thioredoxin interacting protein | 0.05389 |
| GRB10 | growth factor receptor-bound protein 10 | 0.053192 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0531373 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0528232 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0516381 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0513659 |
| RCOR1 | REST corepressor 1 | 0.0512543 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0509606 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.050722 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0501654 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0492089 |
| NF1 | neurofibromin 1 | 0.0489025 |
| RAB10 | RAB10, member RAS oncogene family | 0.0487899 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0485639 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.048511 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0477759 |
| KIAA1217 | KIAA1217 | 0.0477466 |
| USP53 | ubiquitin specific peptidase 53 | 0.0476791 |
| GOLGA4 | golgin A4 | 0.0474071 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0472181 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0468168 |
| FLNB | filamin B, beta | 0.0461004 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0452799 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0439663 |
| YTHDC1 | YTH domain containing 1 | 0.0438241 |
| COG5 | component of oligomeric golgi complex 5 | 0.0437724 |
| RASA2 | RAS p21 protein activator 2 | 0.0436764 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0436073 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0428717 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0428667 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0416467 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0415998 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0408062 |
| KIF5B | kinesin family member 5B | 0.0405967 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0404093 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0394289 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0388879 |
| LAMB3 | laminin, beta 3 | 0.0383153 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0381306 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0380066 |
| TANK | TRAF family member-associated NFKB activator | 0.0371763 |
| CD2AP | CD2-associated protein | 0.0369577 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0363953 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0363728 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.035629 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0353932 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0348601 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0328048 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0326913 |
| GOLGB1 | golgin B1 | 0.0323786 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0323633 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0321419 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0314459 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.031178 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0307133 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0301093 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0291967 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0289336 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0289197 |
| RNF149 | ring finger protein 149 | 0.0286597 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0283864 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0280855 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0279594 |
| NUMB | numb homolog (Drosophila) | 0.0272525 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0267281 |
| RBM39 | RNA binding motif protein 39 | 0.0267044 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0259906 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0259459 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0256378 |
| PCBP2 | poly(rC) binding protein 2 | 0.0255972 |
| SEC24D | SEC24 family member D | 0.025446 |
| DSTN | destrin (actin depolymerizing factor) | 0.025361 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.161872 |
| EGFR | epidermal growth factor receptor | -0.114701 |
| VIM | vimentin | -0.107867 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.10602 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.104535 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.101702 |
| CD44 | CD44 molecule (Indian blood group) | -0.0965494 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0898436 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0887423 |
| RUNX1 | runt-related transcription factor 1 | -0.0839368 |
| LMO7 | LIM domain 7 | -0.0837304 |
| FN1 | fibronectin 1 | -0.0830962 |
| SLTM | SAFB-like, transcription modulator | -0.0815406 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0773316 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0769832 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0758914 |
| INHBA | inhibin, beta A | -0.0741386 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0676229 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0656246 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0624672 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0619098 |
| FBXO11 | F-box protein 11 | -0.0616313 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0606096 |
| ATOSA | atos homolog A | -0.0577884 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0569449 |
| VCL | vinculin | -0.0560967 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0543387 |
| MAP1B | microtubule-associated protein 1B | -0.0542728 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0540353 |
| CALD1 | caldesmon 1 | -0.0538272 |
| LOX | lysyl oxidase | -0.0537708 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0525725 |
| CADM1 | cell adhesion molecule 1 | -0.0505523 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.050086 |
| TMF1 | TATA element modulatory factor 1 | -0.0500646 |
| TPM4 | tropomyosin 4 | -0.0500352 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0493567 |
| SFTPA2 | surfactant protein A2 | -0.0484043 |
| HDAC9 | histone deacetylase 9 | -0.0480928 |
| TMEM165 | transmembrane protein 165 | -0.0468067 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0465514 |
| ETNK1 | ethanolamine kinase 1 | -0.046432 |
| DENND5B | DENN/MADD domain containing 5B | -0.0463459 |
| DST | dystonin | -0.0461495 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0442865 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0441047 |
| ARFGEF3 | ARFGEF family member 3 | -0.0440083 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0435652 |
| GPC6 | glypican 6 | -0.0428584 |
| FRMD5 | FERM domain containing 5 | -0.0426761 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0425821 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0421064 |
| PRELID2 | PRELI domain containing 2 | -0.0420361 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.041723 |
| RPS12 | ribosomal protein S12 | -0.0414322 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0402779 |
| JAK1 | Janus kinase 1 | -0.0402267 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0400238 |
| MT2A | metallothionein 2A | -0.039962 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0397986 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0395402 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0388254 |
| S100A9 | S100 calcium binding protein A9 | -0.0379409 |
| RPL35A | ribosomal protein L35a | -0.0378107 |
| RPS6 | ribosomal protein S6 | -0.0377665 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0376983 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0375517 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0373325 |
| ACTG1 | actin gamma 1 | -0.0372589 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0365365 |
| CLTC | clathrin, heavy chain (Hc) | -0.0355792 |
| POTEF | POTE ankyrin domain family, member F | -0.0349404 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0346195 |
| BPTF | bromodomain PHD finger transcription factor | -0.034132 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0341118 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0339553 |
| TPR | translocated promoter region, nuclear basket protein | -0.0332556 |
| PKM | pyruvate kinase, muscle | -0.0331153 |
| RPL7A | ribosomal protein L7a | -0.0327121 |
| PRKCA | protein kinase C, alpha | -0.0323007 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0319477 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0314867 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0313 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.031276 |
| ENO1 | enolase 1, (alpha) | -0.0310506 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0309118 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0308631 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0307316 |
| SBF2 | SET binding factor 2 | -0.0300198 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0299674 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0299539 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.029779 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0293277 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0284456 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0275079 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0274687 |
| SMAD3 | SMAD family member 3 | -0.02709 |
| ACTN1 | actinin, alpha 1 | -0.0270519 |
| TES | testin LIM domain protein | -0.026974 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.026746 |
