| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.165492 |
| DSCAM | Down syndrome cell adhesion molecule | 0.119905 |
| FN1 | fibronectin 1 | 0.119881 |
| FNDC3B | fibronectin type III domain containing 3B | 0.111007 |
| ASPH | aspartate beta-hydroxylase | 0.108757 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.1066 |
| CANX | calnexin | 0.106585 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.101534 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0995673 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0932041 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0931878 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0892738 |
| CALR | calreticulin | 0.0843441 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0840831 |
| MYO6 | myosin VI | 0.081013 |
| EXT1 | exostosin glycosyltransferase 1 | 0.077922 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0771761 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.076875 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0748743 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0747971 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0728777 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0721401 |
| PTK2 | protein tyrosine kinase 2 | 0.0717065 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0686989 |
| ANXA2 | annexin A2 | 0.0655433 |
| AHNAK | AHNAK nucleoprotein | 0.0653394 |
| FAM13A | family with sequence similarity 13, member A | 0.0612063 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0609654 |
| GOLGA4 | golgin A4 | 0.0602994 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0602322 |
| FLNB | filamin B, beta | 0.0585043 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0582831 |
| SPAG9 | sperm associated antigen 9 | 0.057967 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.057612 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0563087 |
| RCOR1 | REST corepressor 1 | 0.0550294 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0548121 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0545747 |
| LAMC2 | laminin, gamma 2 | 0.0544554 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.053622 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0527614 |
| LMO7 | LIM domain 7 | 0.0520021 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0512003 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0506693 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0505712 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0498592 |
| ERBIN | erbb2 interacting protein | 0.0497856 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0494512 |
| PLEC | plectin | 0.04945 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0493474 |
| HMGB2 | high mobility group box 2 | 0.0486471 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0478615 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0464297 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0461254 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.046067 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0460478 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0459748 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0457083 |
| DTNA | dystrobrevin, alpha | 0.0450459 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0448831 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0448258 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0446133 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0442376 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0441989 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0440567 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0437357 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0436614 |
| VCL | vinculin | 0.0436156 |
| ANXA1 | annexin A1 | 0.0435412 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0435261 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0430679 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0429431 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0425578 |
| DUSP10 | dual specificity phosphatase 10 | 0.0424732 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0419363 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0419033 |
| SMAD3 | SMAD family member 3 | 0.0415621 |
| CTBP2 | C-terminal binding protein 2 | 0.0413921 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.041204 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.041109 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0409634 |
| CD109 | CD109 molecule | 0.0407134 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0398359 |
| RBM39 | RNA binding motif protein 39 | 0.0397978 |
| TMF1 | TATA element modulatory factor 1 | 0.0394662 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0392643 |
| YTHDC1 | YTH domain containing 1 | 0.0391898 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0391638 |
| LAMB3 | laminin, beta 3 | 0.0387568 |
| LDHA | lactate dehydrogenase A | 0.0384207 |
| MYO1E | myosin IE | 0.0378044 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0376815 |
| EFNA5 | ephrin-A5 | 0.0372453 |
| MYO5B | myosin VB | 0.036965 |
| COPA | coatomer protein complex, subunit alpha | 0.0368077 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0364725 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0362896 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0362573 |
| FNIP1 | folliculin interacting protein 1 | 0.0358908 |
| HELZ | helicase with zinc finger | 0.0355831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.208998 |
| POTEF | POTE ankyrin domain family, member F | -0.134846 |
| ACTG1 | actin gamma 1 | -0.106172 |
| FTL | ferritin, light polypeptide | -0.0942204 |
| HMGA1 | high mobility group AT-hook 1 | -0.0921868 |
| TMSB10 | thymosin beta 10 | -0.0896317 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0716052 |
| RPL35A | ribosomal protein L35a | -0.0546838 |
| RPLP1 | ribosomal protein, large, P1 | -0.0484764 |
| MT2A | metallothionein 2A | -0.0480716 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0480441 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0410759 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0333232 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0330204 |
| FOSL1 | FOS-like antigen 1 | -0.031539 |
| RPS6 | ribosomal protein S6 | -0.0315253 |
| RPS19 | ribosomal protein S19 | -0.0305738 |
| RPLP2 | ribosomal protein, large, P2 | -0.029915 |
| RPL28 | ribosomal protein L28 | -0.02927 |
| RPS8 | ribosomal protein S8 | -0.027126 |
| RPS23 | ribosomal protein S23 | -0.0266301 |
| RPL9 | ribosomal protein L9 | -0.0263263 |
| S100A6 | S100 calcium binding protein A6 | -0.0261262 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0258591 |
| RPS14 | ribosomal protein S14 | -0.0258487 |
| RPL8 | ribosomal protein L8 | -0.0253994 |
| NDRG1 | N-myc downstream regulated 1 | -0.0253412 |
| CCND1 | cyclin D1 | -0.0247163 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.024559 |
| PFN1 | profilin 1 | -0.0242767 |
| HMGB1 | high mobility group box 1 | -0.024212 |
| S100A10 | S100 calcium binding protein A10 | -0.0229933 |
| LOC112694756 | uncharaterized LOC112694756 | -0.02142 |
| YBX1 | Y box binding protein 1 | -0.0213153 |
| RPL36 | ribosomal protein L36 | -0.0212325 |
| RPL32 | ribosomal protein L32 | -0.0211113 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0210649 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0207938 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0206356 |
| S100A11 | S100 calcium binding protein A11 | -0.0205186 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0204326 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0203828 |
| MUC1 | mucin 1, cell surface associated | -0.0196463 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0195484 |
| CCNL1 | cyclin L1 | -0.0189965 |
| EGR1 | early growth response 1 | -0.0189705 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0186764 |
| FHIT | fragile histidine triad | -0.0186737 |
| S100A9 | S100 calcium binding protein A9 | -0.0184403 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.0183166 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.0180896 |
| RPL30 | ribosomal protein L30 | -0.0179738 |
| TAPBP | TAP binding protein (tapasin) | -0.0178963 |
| RPL34 | ribosomal protein L34 | -0.0178336 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0176895 |
| RPS25 | ribosomal protein S25 | -0.017081 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0169906 |
| CLDN4 | claudin 4 | -0.016018 |
| RACK1 | receptor for activated C kinase 1 | -0.0159811 |
| TXNRD1 | thioredoxin reductase 1 | -0.0158849 |
| RPS5 | ribosomal protein S5 | -0.0153931 |
| RPL19 | ribosomal protein L19 | -0.0151501 |
| RPL37 | ribosomal protein L37 | -0.0150601 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0150434 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.014983 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.0149492 |
| SYT1 | synaptotagmin I | -0.0148678 |
| RPL35 | ribosomal protein L35 | -0.0147283 |
| RPS15 | ribosomal protein S15 | -0.0145998 |
| RPS20 | ribosomal protein S20 | -0.0145727 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0144588 |
| RPL37A | ribosomal protein L37a | -0.0144152 |
| SFTPA1 | surfactant protein A1 | -0.0138125 |
| IER3 | immediate early response 3 | -0.0137144 |
| GPX1 | glutathione peroxidase 1 | -0.0136814 |
| CST3 | cystatin C | -0.0135025 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0133985 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0133166 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0131693 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0131206 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0130312 |
| GPX4 | glutathione peroxidase 4 | -0.0129173 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0128224 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0127877 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0127689 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0127212 |
| BSG | basigin (Ok blood group) | -0.0126636 |
| S100A4 | S100 calcium binding protein A4 | -0.0126006 |
| TUBA1B | tubulin, alpha 1b | -0.0123735 |
| RHOF | ras homolog family member F (in filopodia) | -0.0122928 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0122675 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0122443 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0122128 |
| FOXP1 | forkhead box P1 | -0.012135 |
| RPS17 | ribosomal protein S17 | -0.0120813 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0120549 |
| RPS11 | ribosomal protein S11 | -0.0119912 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0118742 |
| RPL27 | ribosomal protein L27 | -0.0117161 |
| RPL23A | ribosomal protein L23a | -0.0115744 |
