| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.122017 |
| RUNX1 | runt-related transcription factor 1 | 0.113571 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.10819 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.103811 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0986703 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0986146 |
| RPS6 | ribosomal protein S6 | 0.0976905 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0964689 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0930173 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0917111 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0899252 |
| COG5 | component of oligomeric golgi complex 5 | 0.0872489 |
| DSPP | dentin sialophosphoprotein | 0.0850652 |
| RPLP1 | ribosomal protein, large, P1 | 0.0850462 |
| RPS8 | ribosomal protein S8 | 0.0840878 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0832423 |
| GOLGA4 | golgin A4 | 0.0814847 |
| CANX | calnexin | 0.0783814 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.074121 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.073655 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0729921 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0716524 |
| FAT1 | FAT atypical cadherin 1 | 0.0703009 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0695368 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0686125 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0672448 |
| SBF2 | SET binding factor 2 | 0.0668802 |
| BBX | bobby sox homolog (Drosophila) | 0.0667163 |
| LMO7 | LIM domain 7 | 0.0657398 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0639839 |
| SETD5 | SET domain containing 5 | 0.061872 |
| RPL19 | ribosomal protein L19 | 0.0618432 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.061178 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0591574 |
| SPAG9 | sperm associated antigen 9 | 0.0589543 |
| PGK1 | phosphoglycerate kinase 1 | 0.0588376 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0587321 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0575475 |
| DSCAM | Down syndrome cell adhesion molecule | 0.056898 |
| RPL23 | ribosomal protein L23 | 0.0507303 |
| ANXA2 | annexin A2 | 0.0503373 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0496847 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0493766 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.048716 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0484246 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0467193 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0464971 |
| NUP58 | nucleoporin 58 | 0.0462956 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0462525 |
| RBM39 | RNA binding motif protein 39 | 0.046167 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0451308 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0448325 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0440576 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0410058 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0409766 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0408091 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0395492 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0377935 |
| SEPTIN9 | septin 9 | 0.0364172 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0359533 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0353825 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0350662 |
| NCKAP1 | NCK-associated protein 1 | 0.0341156 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0340452 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.033729 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0328704 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.032642 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0326125 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0311401 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0305582 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0297653 |
| CTBP2 | C-terminal binding protein 2 | 0.0293484 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0292819 |
| JMJD1C | jumonji domain containing 1C | 0.0292401 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0291584 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0291382 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0285568 |
| ENO1 | enolase 1, (alpha) | 0.0284092 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0282758 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0280182 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0278918 |
| MYO1E | myosin IE | 0.0276921 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0275486 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0262866 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0262318 |
| ACTN4 | actinin, alpha 4 | 0.0251307 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0243223 |
| SLTM | SAFB-like, transcription modulator | 0.0242847 |
| FLNB | filamin B, beta | 0.0235357 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.022296 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0219172 |
| PDLIM5 | PDZ and LIM domain 5 | 0.021458 |
| FMNL2 | formin-like 2 | 0.0213633 |
| PKM | pyruvate kinase, muscle | 0.0212678 |
| DTNA | dystrobrevin, alpha | 0.0212456 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0206698 |
| FNIP1 | folliculin interacting protein 1 | 0.0204989 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0197111 |
| ZNF207 | zinc finger protein 207 | 0.0190547 |
| IER3 | immediate early response 3 | 0.0189132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260154 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.184599 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.152273 |
| EFNA5 | ephrin-A5 | -0.14102 |
| IGF2 | insulin-like growth factor 2 | -0.122535 |
| GPC6 | glypican 6 | -0.12197 |
| PDE10A | phosphodiesterase 10A | -0.105604 |
| VIM | vimentin | -0.100227 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0997434 |
| PRKCA | protein kinase C, alpha | -0.096984 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0886662 |
| RORA | RAR-related orphan receptor A | -0.0884196 |
| FN1 | fibronectin 1 | -0.0846813 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0836503 |
| SMYD3 | SET and MYND domain containing 3 | -0.0816735 |
| PARD3 | par-3 family cell polarity regulator | -0.0787948 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0767683 |
| TENM3 | teneurin transmembrane protein 3 | -0.0759434 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0743894 |
| VCL | vinculin | -0.0739389 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0709986 |
| EGR1 | early growth response 1 | -0.070662 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0701424 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0693008 |
| NAV2 | neuron navigator 2 | -0.0657489 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0644339 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0636535 |
| FTL | ferritin, light polypeptide | -0.0632817 |
| INTS6 | integrator complex subunit 6 | -0.0632607 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0631245 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.062584 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0603836 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0568806 |
| MED13L | mediator complex subunit 13-like | -0.0567125 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0556726 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0553524 |
| BPTF | bromodomain PHD finger transcription factor | -0.0553502 |
| STC1 | stanniocalcin 1 | -0.0551494 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.054702 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0537694 |
| ASPH | aspartate beta-hydroxylase | -0.0534725 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0515903 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0472761 |
| APP | amyloid beta (A4) precursor protein | -0.0466394 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0446493 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0442415 |
| ZNF638 | zinc finger protein 638 | -0.0419283 |
| RAD51B | RAD51 paralog B | -0.0416115 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0415575 |
| NDRG1 | N-myc downstream regulated 1 | -0.040715 |
| EGFR | epidermal growth factor receptor | -0.0357704 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0350916 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0345101 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0339444 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0334008 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0322936 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0318597 |
| NHSL1 | NHS-like 1 | -0.031722 |
| WASF2 | WAS protein family, member 2 | -0.031541 |
| NLGN1 | neuroligin 1 | -0.0314358 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0311982 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0305898 |
| CMIP | c-Maf inducing protein | -0.0305062 |
| FGF14 | fibroblast growth factor 14 | -0.0289389 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0280296 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0276196 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0276043 |
| STK24 | serine/threonine kinase 24 | -0.0275386 |
| HDLBP | high density lipoprotein binding protein | -0.0275055 |
| MT2A | metallothionein 2A | -0.0274753 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0266363 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0265089 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0256947 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0256841 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0255967 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0254559 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0253359 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0247159 |
| CDH13 | cadherin 13 | -0.0246398 |
| LAMB3 | laminin, beta 3 | -0.0245181 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0239842 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0239273 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0237618 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0233303 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0232995 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0231623 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0230792 |
| KLF12 | Kruppel-like factor 12 | -0.0221894 |
| CUX1 | cut-like homeobox 1 | -0.0218303 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0216678 |
| DSTN | destrin (actin depolymerizing factor) | -0.0214643 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0214598 |
| SMAD3 | SMAD family member 3 | -0.0213765 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0210123 |
| LDHA | lactate dehydrogenase A | -0.0208984 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0201577 |
| KIZ | kizuna centrosomal protein | -0.0201118 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0200917 |
| GPHN | gephyrin | -0.0189088 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0186112 |
