| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pioglitazone_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.162478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.128736 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0904512 |
| OGA | O-GlcNAcase | 0.082617 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0714844 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0687532 |
| FN1 | fibronectin 1 | 0.0678614 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0667351 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0665681 |
| ARRDC3 | arrestin domain containing 3 | 0.0640403 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0588134 |
| ZNF292 | zinc finger protein 292 | 0.0579213 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0576832 |
| SPAG9 | sperm associated antigen 9 | 0.0561382 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0518582 |
| GOLGA4 | golgin A4 | 0.0504543 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0481486 |
| ANXA2 | annexin A2 | 0.0471758 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0453845 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0440847 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0436835 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0423041 |
| ANLN | anillin, actin binding protein | 0.0415054 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0405427 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0399108 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0387347 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0383262 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.036623 |
| SERINC1 | serine incorporator 1 | 0.03619 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0359897 |
| MKI67 | marker of proliferation Ki-67 | 0.0356769 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0353673 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.034633 |
| HELZ | helicase with zinc finger | 0.0342821 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0342312 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.034104 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0327399 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0325657 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0324085 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0323566 |
| MATR3 | matrin 3 | 0.0322045 |
| RLF | rearranged L-myc fusion | 0.0321651 |
| APP | amyloid beta (A4) precursor protein | 0.0313175 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0311489 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0295198 |
| PCBP2 | poly(rC) binding protein 2 | 0.0286658 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0284134 |
| CANX | calnexin | 0.0276628 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0271951 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0268972 |
| CEP250 | centrosomal protein 250kDa | 0.0268408 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0267762 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0266025 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0265511 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0263645 |
| YTHDC1 | YTH domain containing 1 | 0.0260402 |
| RPL7 | ribosomal protein L7 | 0.0256887 |
| USP37 | ubiquitin specific peptidase 37 | 0.0256079 |
| ATP13A3 | ATPase type 13A3 | 0.0253396 |
| RNF145 | ring finger protein 145 | 0.0248818 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0247782 |
| NEK7 | NIMA-related kinase 7 | 0.0247023 |
| PHIP | pleckstrin homology domain interacting protein | 0.0247 |
| RBM39 | RNA binding motif protein 39 | 0.0246335 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0244483 |
| FMNL2 | formin-like 2 | 0.0243126 |
| AHNAK | AHNAK nucleoprotein | 0.0241966 |
| OPTN | optineurin | 0.0240727 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0240232 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0237814 |
| NAV2 | neuron navigator 2 | 0.0237624 |
| WTAP | Wilms tumor 1 associated protein | 0.0237506 |
| KIF4A | kinesin family member 4A | 0.0236243 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0235564 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0235235 |
| CENPF | centromere protein F, 350/400kDa | 0.0234387 |
| SRP54 | signal recognition particle 54kDa | 0.0233869 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0232493 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0230666 |
| ZNF654 | zinc finger protein 654 | 0.0229719 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0226668 |
| NUP58 | nucleoporin 58 | 0.0225585 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0225433 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0224561 |
| AHR | aryl hydrocarbon receptor | 0.0224343 |
| ADM | adrenomedullin | 0.0223192 |
| NUP153 | nucleoporin 153kDa | 0.022217 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0222002 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0221239 |
| RPL14 | ribosomal protein L14 | 0.0221076 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0221015 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0219451 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0219259 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0217104 |
| XPO1 | exportin 1 | 0.0216391 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0215964 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0213654 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0211732 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.021156 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0208781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.222145 |
| FRMD4A | FERM domain containing 4A | -0.180778 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.167125 |
| GLIS3 | GLIS family zinc finger 3 | -0.165077 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.123914 |
| HLA-B | major histocompatibility complex, class I, B | -0.108685 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.105044 |
| HMGA2 | high mobility group AT-hook 2 | -0.100326 |
| TMSB10 | thymosin beta 10 | -0.0967496 |
| CD44 | CD44 molecule (Indian blood group) | -0.0878965 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0851506 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0848601 |
| CDH13 | cadherin 13 | -0.0806089 |
| EGR1 | early growth response 1 | -0.0797133 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0766497 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0756998 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0728873 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0724492 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0702536 |
| VCL | vinculin | -0.0698449 |
| NAV1 | neuron navigator 1 | -0.0690836 |
| BICC1 | BicC family RNA binding protein 1 | -0.068358 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0634462 |
| IER3 | immediate early response 3 | -0.0620735 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0620156 |
| FTL | ferritin, light polypeptide | -0.0593587 |
| C3 | complement component 3 | -0.0569885 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0562892 |
| CTSD | cathepsin D | -0.0557635 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0547449 |
| TMEM132D | transmembrane protein 132D | -0.0540645 |
| EGFR | epidermal growth factor receptor | -0.053669 |
| DIAPH2 | diaphanous-related formin 2 | -0.0536287 |
| HDAC9 | histone deacetylase 9 | -0.0518529 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0504532 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0491699 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0486661 |
| VCAN | versican | -0.0482087 |
| TNS3 | tensin 3 | -0.0478828 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0461943 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0457868 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0443884 |
| HLA-A | major histocompatibility complex, class I, A | -0.0441493 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0441441 |
| DST | dystonin | -0.0437749 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0429334 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0427624 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0414634 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0413707 |
| CLMP | CXADR-like membrane protein | -0.0408323 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.040101 |
| RAI14 | retinoic acid induced 14 | -0.0397052 |
| ATXN1 | ataxin 1 | -0.0393333 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0393143 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0392144 |
| GPC6 | glypican 6 | -0.0391627 |
| NABP1 | nucleic acid binding protein 1 | -0.0385207 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0380842 |
| ASPH | aspartate beta-hydroxylase | -0.0378256 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376725 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0376715 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0376268 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0368932 |
| MT2A | metallothionein 2A | -0.0367405 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0365235 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0360443 |
| RNF213 | ring finger protein 213 | -0.0352509 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0351745 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0349738 |
| RAD51B | RAD51 paralog B | -0.034875 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0345633 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0345201 |
| COL5A1 | collagen, type V, alpha 1 | -0.0344401 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0340513 |
| PLIN2 | perilipin 2 | -0.0339276 |
| TPM1 | tropomyosin 1 (alpha) | -0.0335909 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0324367 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0320652 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0317264 |
| TENM2 | teneurin transmembrane protein 2 | -0.0315812 |
| BNC2 | basonuclin 2 | -0.0309613 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0308383 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0304566 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0303339 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0301134 |
| EFNA5 | ephrin-A5 | -0.0299563 |
| HMGA1 | high mobility group AT-hook 1 | -0.0298533 |
| VEGFA | vascular endothelial growth factor A | -0.0296699 |
| ACTG1 | actin gamma 1 | -0.0293341 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0292671 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0291694 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0287453 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0287433 |
| LDHA | lactate dehydrogenase A | -0.0287059 |
| COL1A1 | collagen, type I, alpha 1 | -0.0286847 |
| MAP1B | microtubule-associated protein 1B | -0.0279823 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0279446 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0278052 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0276804 |
| LOX | lysyl oxidase | -0.0276066 |
