| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pioglitazone perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pioglitazone_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0775668 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0731402 |
| SET | SET nuclear proto-oncogene | 0.0391533 |
| INSIG1 | insulin induced gene 1 | 0.0390951 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0388993 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0381998 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0379007 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0374169 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0373771 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0362891 |
| MKI67 | marker of proliferation Ki-67 | 0.0358491 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0341567 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0335115 |
| SRP54 | signal recognition particle 54kDa | 0.0332549 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0331588 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0324988 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0323101 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0317674 |
| RPL12 | ribosomal protein L12 | 0.0311667 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0307257 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0305405 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.030179 |
| ECT2 | epithelial cell transforming 2 | 0.0298027 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0290082 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0284896 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0275997 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.027016 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0264291 |
| IPO5 | importin 5 | 0.0258726 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.02551 |
| CENPF | centromere protein F, 350/400kDa | 0.0253869 |
| CEP250 | centrosomal protein 250kDa | 0.0252314 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0250604 |
| STX18 | syntaxin 18 | 0.0250017 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0248837 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0248356 |
| SPAG9 | sperm associated antigen 9 | 0.0240772 |
| RPL23 | ribosomal protein L23 | 0.0240543 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0240252 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.023976 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0238583 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0237128 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0236088 |
| TMEM248 | transmembrane protein 248 | 0.0235737 |
| HMGB2 | high mobility group box 2 | 0.0233993 |
| RSRP1 | arginine/serine-rich protein 1 | 0.023328 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0230187 |
| KNL1 | kinetochore scaffold 1 | 0.0229772 |
| RASA2 | RAS p21 protein activator 2 | 0.0229646 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0223622 |
| PHF3 | PHD finger protein 3 | 0.0222038 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0217712 |
| XPO6 | exportin 6 | 0.0215379 |
| MSN | moesin | 0.0214683 |
| KIF23 | kinesin family member 23 | 0.0213713 |
| ETNK1 | ethanolamine kinase 1 | 0.0211102 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.0210729 |
| SETD5 | SET domain containing 5 | 0.0210373 |
| PDE10A | phosphodiesterase 10A | 0.0207989 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0207787 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0207061 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0205857 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0204367 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0203766 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0200479 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.0198767 |
| MMS22L | MMS22-like, DNA repair protein | 0.0198465 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0197326 |
| MYO1D | myosin ID | 0.0196391 |
| TPX2 | TPX2, microtubule-associated | 0.0196096 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.0194916 |
| ANXA1 | annexin A1 | 0.0194564 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0194541 |
| SPAG5 | sperm associated antigen 5 | 0.0194092 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0193454 |
| HJURP | Holliday junction recognition protein | 0.0192031 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0191816 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0191791 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0191594 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0191557 |
| CCNL1 | cyclin L1 | 0.0191468 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0190889 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0190782 |
| NUCB2 | nucleobindin 2 | 0.0190372 |
| TPM3 | tropomyosin 3 | 0.0189225 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0189081 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0188749 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | 0.018853 |
| RPL19 | ribosomal protein L19 | 0.0188446 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0187796 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0187665 |
| FANCI | Fanconi anemia, complementation group I | 0.018718 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0186489 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0186042 |
| RCOR1 | REST corepressor 1 | 0.0184853 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 0.0184536 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0184519 |
| PCBP3 | poly(rC) binding protein 3 | 0.0184494 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0184084 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.0183808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.210076 |
| FNDC3B | fibronectin type III domain containing 3B | -0.123458 |
| TMSB10 | thymosin beta 10 | -0.104418 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0969742 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0930714 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0929124 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0875583 |
| DST | dystonin | -0.0814193 |
| SMYD3 | SET and MYND domain containing 3 | -0.0735629 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0725654 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0668866 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0666892 |
| FMN1 | formin 1 | -0.0642579 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.061333 |
| PRKCA | protein kinase C, alpha | -0.0603886 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.059887 |
| HMGA2 | high mobility group AT-hook 2 | -0.0597819 |
| IGF2 | insulin-like growth factor 2 | -0.0576304 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0528884 |
| FMNL2 | formin-like 2 | -0.0522312 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0505769 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0499329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0488698 |
| ATG7 | autophagy related 7 | -0.0483451 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0479019 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0474208 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0461582 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0443171 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0429457 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0418647 |
| MYO9A | myosin IXA | -0.0412252 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0411733 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0411138 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0408956 |
| CD44 | CD44 molecule (Indian blood group) | -0.0408886 |
| OSMR | oncostatin M receptor | -0.0405791 |
| ERBIN | erbb2 interacting protein | -0.040439 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0402996 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0402792 |
| FLNB | filamin B, beta | -0.0397215 |
| DSCAM | Down syndrome cell adhesion molecule | -0.039627 |
| RIGI | RNA sensor RIG-I | -0.0396037 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0393988 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.038313 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0380406 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0379911 |
| FAM3C | family with sequence similarity 3, member C | -0.0378684 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0376467 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0376153 |
| POTEF | POTE ankyrin domain family, member F | -0.0374027 |
| PKM | pyruvate kinase, muscle | -0.0372386 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0366875 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0361639 |
| PCNX4 | pecanex 4 | -0.0359349 |
| ATM | ATM serine/threonine kinase | -0.0354302 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0352298 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0351566 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0346128 |
| SVIL | supervillin | -0.034573 |
| AHNAK | AHNAK nucleoprotein | -0.0345561 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0341615 |
| PARD3 | par-3 family cell polarity regulator | -0.0338841 |
| ANGPTL4 | angiopoietin-like 4 | -0.0337648 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0336761 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0329118 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.032841 |
| VIM | vimentin | -0.0328262 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0327961 |
| ATXN1 | ataxin 1 | -0.0319801 |
| ATG10 | autophagy related 10 | -0.0319154 |
| PRSS23 | protease, serine, 23 | -0.0318052 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0317568 |
| NAV3 | neuron navigator 3 | -0.031658 |
| FNIP1 | folliculin interacting protein 1 | -0.0315282 |
| RAD51B | RAD51 paralog B | -0.0312551 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0310974 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0308581 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0303774 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0302898 |
| TAOK1 | TAO kinase 1 | -0.0298541 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0297652 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0296779 |
| SQSTM1 | sequestosome 1 | -0.0296307 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0296002 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0295944 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0295669 |
| UBC | ubiquitin C | -0.0294624 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0293951 |
| PCED1B | PC-esterase domain containing 1B | -0.0291753 |
| EFNA5 | ephrin-A5 | -0.0286702 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0286104 |
| NALCN | sodium leak channel, non selective | -0.0282781 |
| TAOK3 | TAO kinase 3 | -0.0280301 |
| ZNF609 | zinc finger protein 609 | -0.0280253 |
| PRR16 | proline rich 16 | -0.0279272 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0277371 |
| CYTH1 | cytohesin 1 | -0.0276628 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.0275659 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0274969 |
| STXBP1 | syntaxin binding protein 1 | -0.0274579 |
