| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Piroxicam_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.417535 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.148915 |
| VEGFA | vascular endothelial growth factor A | 0.101004 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.050274 |
| SEPTIN9 | septin 9 | 0.0496146 |
| PLAT | plasminogen activator, tissue | 0.0433006 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0412892 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0346262 |
| GPC5 | glypican 5 | 0.0345478 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0343164 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0329479 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0326832 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0319075 |
| SMAD3 | SMAD family member 3 | 0.0317466 |
| GOLGA4 | golgin A4 | 0.0304572 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0288609 |
| NDRG1 | N-myc downstream regulated 1 | 0.0286191 |
| SSH1 | slingshot protein phosphatase 1 | 0.028394 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0281889 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0270665 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0268782 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0268443 |
| WDR45B | WD repeat domain 45B | 0.0256182 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0255358 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.025319 |
| DNMBP | dynamin binding protein | 0.0247836 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0245812 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245397 |
| USP36 | ubiquitin specific peptidase 36 | 0.0242 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0240937 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0240851 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0240694 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0236349 |
| YTHDC1 | YTH domain containing 1 | 0.023622 |
| MATR3 | matrin 3 | 0.0233521 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0231839 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.02221 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0218225 |
| ARRDC3 | arrestin domain containing 3 | 0.0215517 |
| FNBP1 | formin binding protein 1 | 0.0215205 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0212576 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0209464 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0206519 |
| FAM13A | family with sequence similarity 13, member A | 0.0204784 |
| LPIN1 | lipin 1 | 0.020383 |
| PRPF3 | pre-mRNA processing factor 3 | 0.019524 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0194171 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0193879 |
| RARA | retinoic acid receptor, alpha | 0.0193639 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0193405 |
| APP | amyloid beta (A4) precursor protein | 0.0193038 |
| HDAC5 | histone deacetylase 5 | 0.019282 |
| CASC3 | cancer susceptibility candidate 3 | 0.0191427 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0190884 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0190195 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0188512 |
| ZNF146 | zinc finger protein 146 | 0.018787 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0183215 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0178292 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0176378 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0173429 |
| SFTPA2 | surfactant protein A2 | 0.0173249 |
| RPL37A | ribosomal protein L37a | 0.0173002 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0172464 |
| CDC27 | cell division cycle 27 | 0.017239 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0171794 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0171599 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0170175 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0169894 |
| AFDN | afadin, adherens junction formation factor | 0.0168251 |
| WDR43 | WD repeat domain 43 | 0.0167124 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0166977 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0166869 |
| MEF2A | myocyte enhancer factor 2A | 0.0166395 |
| ZFP36 | ZFP36 ring finger protein | 0.0163291 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0160913 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0159904 |
| MMP2 | matrix metallopeptidase 2 | 0.0158324 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0158043 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0156871 |
| ANGPTL4 | angiopoietin-like 4 | 0.0156448 |
| MEF2D | myocyte enhancer factor 2D | 0.0155573 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0154313 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0153824 |
| SET | SET nuclear proto-oncogene | 0.015363 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0152841 |
| CTSB | cathepsin B | 0.015248 |
| OGA | O-GlcNAcase | 0.0152398 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0152268 |
| TOB1 | transducer of ERBB2, 1 | 0.0151873 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0149618 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0149551 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0149527 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0148002 |
| L1CAM | L1 cell adhesion molecule | 0.0146549 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor | 0.0146281 |
| CCNL1 | cyclin L1 | 0.0144951 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.014462 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0143041 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.014261 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.272181 |
| LSAMP | limbic system-associated membrane protein | -0.192629 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.163992 |
| NRG1 | neuregulin 1 | -0.11719 |
| SYT1 | synaptotagmin I | -0.1085 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.106675 |
| VCL | vinculin | -0.0860208 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0751904 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0694988 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.067523 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0640693 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0615486 |
| PCDH9 | protocadherin 9 | -0.0613877 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0567559 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0556168 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.054353 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.05358 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0526669 |
| ZNF804A | zinc finger protein 804A | -0.0525691 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0501787 |
| NREP | neuronal regeneration related protein | -0.050143 |
| MEIS2 | Meis homeobox 2 | -0.0486585 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0473184 |
| TRIB2 | tribbles pseudokinase 2 | -0.045632 |
| FMN1 | formin 1 | -0.0435777 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0434406 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0427431 |
| CADM2 | cell adhesion molecule 2 | -0.0425026 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0407171 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0400815 |
| RPS24 | ribosomal protein S24 | -0.0396932 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0391535 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0380526 |
| AHNAK | AHNAK nucleoprotein | -0.0380463 |
| PRKCA | protein kinase C, alpha | -0.0379939 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0378695 |
| COL3A1 | collagen, type III, alpha 1 | -0.0366489 |
| BPTF | bromodomain PHD finger transcription factor | -0.0361936 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0361555 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0358377 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.034638 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0345082 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0344818 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0340871 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0336843 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0335559 |
| DTNA | dystrobrevin, alpha | -0.0331725 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0329366 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0326901 |
| RPL35A | ribosomal protein L35a | -0.0323964 |
| EFNA5 | ephrin-A5 | -0.0323389 |
| MED13 | mediator complex subunit 13 | -0.0321741 |
| EXOC4 | exocyst complex component 4 | -0.0320402 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0317624 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.031746 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0316711 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0313949 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0313475 |
| PTK2 | protein tyrosine kinase 2 | -0.0306515 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.030476 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0304378 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0300312 |
| RALYL | RALY RNA binding protein-like | -0.0299585 |
| DACH2 | dachshund family transcription factor 2 | -0.0298434 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.029639 |
| CNTN4 | contactin 4 | -0.029546 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0293095 |
| CUX1 | cut-like homeobox 1 | -0.0286872 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0286854 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0286544 |
| NF1 | neurofibromin 1 | -0.0286117 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0284572 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0280783 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0279463 |
| GATA3 | GATA binding protein 3 | -0.0278156 |
| FOXP1 | forkhead box P1 | -0.0277742 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0274315 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0270222 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0268645 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0266509 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.026562 |
| TPM1 | tropomyosin 1 (alpha) | -0.0263656 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.026124 |
| KLHL13 | kelch-like family member 13 | -0.0260366 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0258578 |
| NFIB | nuclear factor I/B | -0.0257828 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0249555 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0248943 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0247051 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.02461 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0240511 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0239574 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0237649 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0237485 |
| ASPH | aspartate beta-hydroxylase | -0.0236022 |
| FRMD4A | FERM domain containing 4A | -0.0234878 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0232582 |
| RPLP0 | ribosomal protein, large, P0 | -0.0231595 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.022844 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0228215 |
