| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.117438 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0841684 |
| MLPH | melanophilin | 0.059205 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0453703 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0413474 |
| MKI67 | marker of proliferation Ki-67 | 0.0382742 |
| RNF43 | ring finger protein 43 | 0.0373281 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0371972 |
| ARRDC3 | arrestin domain containing 3 | 0.036789 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.033853 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0319512 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0308102 |
| FAT1 | FAT atypical cadherin 1 | 0.0307454 |
| HLA-B | major histocompatibility complex, class I, B | 0.0303199 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0278298 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.027372 |
| PADI1 | peptidyl arginine deiminase, type I | 0.026544 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0264172 |
| H1-0 | H1.0 linker histone | 0.0263179 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0261975 |
| PRRC2C | proline-rich coiled-coil 2C | 0.02587 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0243085 |
| CST3 | cystatin C | 0.023889 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0234114 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.022824 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0228134 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0224485 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0224037 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0219459 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0216015 |
| PRELID2 | PRELI domain containing 2 | 0.0206503 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.019852 |
| EHF | ets homologous factor | 0.0195721 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0195711 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.019041 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0189839 |
| MATR3 | matrin 3 | 0.0187252 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0186859 |
| HPCAL1 | hippocalcin-like 1 | 0.0186649 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0184693 |
| OGA | O-GlcNAcase | 0.0183009 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0181789 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | 0.017903 |
| ZNF160 | zinc finger protein 160 | 0.0174969 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0174301 |
| TSPYL2 | TSPY-like 2 | 0.0173219 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0172919 |
| EFHD2 | EF-hand domain family, member D2 | 0.0172478 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0172428 |
| TPR | translocated promoter region, nuclear basket protein | 0.0168138 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0166436 |
| CLDN4 | claudin 4 | 0.0163976 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0162095 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0161393 |
| MINK1 | misshapen-like kinase 1 | 0.0160898 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0158349 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0158041 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0157867 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0156757 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0156253 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0155545 |
| BRD9 | bromodomain containing 9 | 0.0155145 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0153707 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0153331 |
| DNM2 | dynamin 2 | 0.0153201 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0147332 |
| AOPEP | aminopeptidase O (putative) | 0.0147008 |
| SMAD3 | SMAD family member 3 | 0.014548 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0145185 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0144953 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0143584 |
| CD68 | CD68 molecule | 0.0143536 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0142962 |
| ZNF841 | zinc finger protein 841 | 0.014151 |
| CENPF | centromere protein F, 350/400kDa | 0.0140151 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0138344 |
| MYO5B | myosin VB | 0.0138264 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.013798 |
| ATP10B | ATPase, class V, type 10B | 0.0137505 |
| CTTN | cortactin | 0.0136636 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0135133 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0134758 |
| SET | SET nuclear proto-oncogene | 0.0133968 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0133378 |
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.0133004 |
| SH3BP2 | SH3-domain binding protein 2 | 0.0131416 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 | 0.0130825 |
| PLXNB2 | plexin B2 | 0.0130149 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0128438 |
| LDHA | lactate dehydrogenase A | 0.0128381 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0127426 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.0127286 |
| USP47 | ubiquitin specific peptidase 47 | 0.0127087 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0126672 |
| SELENOF | selenoprotein F | 0.012658 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0125622 |
| QRICH1 | glutamine-rich 1 | 0.0124065 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0123268 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0123104 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0120873 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.185879 |
| LMO7 | LIM domain 7 | -0.166659 |
| PERP | PERP, TP53 apoptosis effector | -0.119686 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.117498 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.109777 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.109309 |
| ANXA2 | annexin A2 | -0.109154 |
| LYZ | lysozyme | -0.107384 |
| EGR1 | early growth response 1 | -0.10633 |
| RNF213 | ring finger protein 213 | -0.102101 |
| EZR | ezrin | -0.0959425 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0941266 |
| RIGI | RNA sensor RIG-I | -0.0929204 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0874998 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0861942 |
| SP100 | SP100 nuclear antigen | -0.085735 |
| MX1 | MX dynamin-like GTPase 1 | -0.0840557 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0813533 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0807117 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0799052 |
| ERBIN | erbb2 interacting protein | -0.079592 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0786154 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0768786 |
| PLSCR1 | phospholipid scramblase 1 | -0.0749932 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0746381 |
| INTS6 | integrator complex subunit 6 | -0.0733916 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0708223 |
| NDRG1 | N-myc downstream regulated 1 | -0.0660463 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0649943 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0648421 |
| MX2 | MX dynamin-like GTPase 2 | -0.0637852 |
| AHI1 | Abelson helper integration site 1 | -0.0622066 |
| CANX | calnexin | -0.060991 |
| NPSR1 | neuropeptide S receptor 1 | -0.0609075 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0604232 |
| MYO1E | myosin IE | -0.0581902 |
| ZNF292 | zinc finger protein 292 | -0.0572091 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0566036 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0549147 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0545116 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0526723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0525406 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0525268 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.052526 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.052467 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0510278 |
| TJP1 | tight junction protein 1 | -0.0508506 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0505898 |
| AREG | amphiregulin | -0.0499488 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0490752 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0490483 |
| SPAG9 | sperm associated antigen 9 | -0.0487987 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0474638 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0473567 |
| VCL | vinculin | -0.0472192 |
| VMP1 | vacuole membrane protein 1 | -0.0471393 |
| UBC | ubiquitin C | -0.0469198 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.046197 |
| XAF1 | XIAP associated factor 1 | -0.0444182 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0435095 |
| ABLIM1 | actin binding LIM protein 1 | -0.0421929 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0421704 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0417702 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0417672 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0408159 |
| TMC5 | transmembrane channel-like 5 | -0.0407382 |
| MAP7 | microtubule-associated protein 7 | -0.0407014 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0406913 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0402276 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0398867 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0395428 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0395287 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0391447 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.038956 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0388871 |
| PKM | pyruvate kinase, muscle | -0.0388353 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0386971 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0386896 |
| IRF1 | interferon regulatory factor 1 | -0.0385259 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0382313 |
| HLA-E | major histocompatibility complex, class I, E | -0.0381127 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.03784 |
| PLSCR2 | phospholipid scramblase 2 | -0.0376345 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0375866 |
| ITGA6 | integrin, alpha 6 | -0.0370083 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0370081 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0366409 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0362244 |
| MCL1 | myeloid cell leukemia 1 | -0.0360778 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0360721 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0357563 |
| RBM47 | RNA binding motif protein 47 | -0.0356268 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0355691 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0355236 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0354256 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0354203 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0354108 |
| SERINC5 | serine incorporator 5 | -0.0341983 |
| DGKH | diacylglycerol kinase, eta | -0.0339116 |
| JUN | jun proto-oncogene | -0.0338262 |