| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.357975 |
| CD44 | CD44 molecule (Indian blood group) | 0.16809 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0970654 |
| FN1 | fibronectin 1 | 0.0969568 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0927414 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.082694 |
| MT2A | metallothionein 2A | 0.0768645 |
| COL5A1 | collagen, type V, alpha 1 | 0.0688213 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0669532 |
| CST3 | cystatin C | 0.0657768 |
| RPS3 | ribosomal protein S3 | 0.0639976 |
| CALR | calreticulin | 0.0572263 |
| TMSB10 | thymosin beta 10 | 0.0553536 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0544216 |
| IER3 | immediate early response 3 | 0.0508871 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0490255 |
| FTL | ferritin, light polypeptide | 0.0475526 |
| RACK1 | receptor for activated C kinase 1 | 0.0462945 |
| PLEC | plectin | 0.0454528 |
| RPL36 | ribosomal protein L36 | 0.0453947 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0444978 |
| PTMA | prothymosin, alpha | 0.0442916 |
| HLA-B | major histocompatibility complex, class I, B | 0.0410575 |
| LDHA | lactate dehydrogenase A | 0.040111 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0387525 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0375606 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0371876 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0369857 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0369564 |
| H1-0 | H1.0 linker histone | 0.0367709 |
| ENO1 | enolase 1, (alpha) | 0.0365836 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0364353 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0360212 |
| ECE1 | endothelin converting enzyme 1 | 0.0359488 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0351852 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0338393 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0335497 |
| VCAN | versican | 0.033263 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.033053 |
| RPS6 | ribosomal protein S6 | 0.0325133 |
| RPS19 | ribosomal protein S19 | 0.0324627 |
| RPL23 | ribosomal protein L23 | 0.0306299 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0304511 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0303554 |
| EGFR | epidermal growth factor receptor | 0.0299971 |
| LOXL2 | lysyl oxidase-like 2 | 0.0298043 |
| NUCB1 | nucleobindin 1 | 0.0297915 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0296785 |
| FLNA | filamin A, alpha | 0.0292105 |
| CADM1 | cell adhesion molecule 1 | 0.0283731 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0282664 |
| RPS8 | ribosomal protein S8 | 0.0280993 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0280761 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0279485 |
| RPL26 | ribosomal protein L26 | 0.0279189 |
| RPL18 | ribosomal protein L18 | 0.0278052 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0277901 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0277581 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0271085 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0270332 |
| IL6 | interleukin 6 | 0.0268544 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0267599 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.026312 |
| S100A9 | S100 calcium binding protein A9 | 0.0257266 |
| LRRC59 | leucine rich repeat containing 59 | 0.0256295 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0255956 |
| B2M | beta-2-microglobulin | 0.0252517 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.0250812 |
| CDH13 | cadherin 13 | 0.0249825 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0249435 |
| SSR1 | signal sequence receptor, alpha | 0.0248626 |
| RPL13A | ribosomal protein L13a | 0.0245237 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0243296 |
| RRBP1 | ribosome binding protein 1 | 0.0242161 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.0240114 |
| ANXA6 | annexin A6 | 0.0239767 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0238037 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0230203 |
| RPS2 | ribosomal protein S2 | 0.0230131 |
| NAV1 | neuron navigator 1 | 0.0227509 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0227146 |
| ACTG1 | actin gamma 1 | 0.0223472 |
| RPL11 | ribosomal protein L11 | 0.0222827 |
| MKI67 | marker of proliferation Ki-67 | 0.02227 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0221152 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0220814 |
| RIGI | RNA sensor RIG-I | 0.0220695 |
| RPS12 | ribosomal protein S12 | 0.0217851 |
| ARRDC3 | arrestin domain containing 3 | 0.0215647 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0215201 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.021438 |
| CAVIN1 | caveolae associated protein 1 | 0.0210386 |
| MED15 | mediator complex subunit 15 | 0.0209065 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0209054 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0204946 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0204335 |
| TMSB4X | thymosin beta 4, X-linked | 0.0204242 |
| PTN | pleiotrophin | 0.0202885 |
| RPS21 | ribosomal protein S21 | 0.0202528 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0199533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.182946 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.169555 |
| NDRG1 | N-myc downstream regulated 1 | -0.149564 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.147751 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.107584 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.107141 |
| COL1A2 | collagen, type I, alpha 2 | -0.101615 |
| POSTN | periostin, osteoblast specific factor | -0.0835156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0822808 |
| TPM4 | tropomyosin 4 | -0.071528 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0714361 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0707294 |
| CANX | calnexin | -0.0612777 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0594594 |
| GOLGA4 | golgin A4 | -0.0550974 |
| CLIC4 | chloride intracellular channel 4 | -0.0517541 |
| LOX | lysyl oxidase | -0.051339 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0474845 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0456871 |
| FBN1 | fibrillin 1 | -0.0452362 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0447647 |
| TAPBP | TAP binding protein (tapasin) | -0.0438932 |
| NKTR | natural killer cell triggering receptor | -0.0436569 |
| PTK2 | protein tyrosine kinase 2 | -0.0427946 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0413465 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0407004 |
| TRAM1 | translocation associated membrane protein 1 | -0.0404714 |
| UBC | ubiquitin C | -0.0391262 |
| CLINT1 | clathrin interactor 1 | -0.0385835 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0383155 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0382629 |
| RBM39 | RNA binding motif protein 39 | -0.0381399 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.037809 |
| USP34 | ubiquitin specific peptidase 34 | -0.0373727 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367591 |
| ATP13A3 | ATPase type 13A3 | -0.0367458 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0361679 |
| COPA | coatomer protein complex, subunit alpha | -0.0361012 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0347304 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0344808 |
| VMP1 | vacuole membrane protein 1 | -0.0343289 |
| SPAG9 | sperm associated antigen 9 | -0.0342787 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.033743 |
| AHNAK | AHNAK nucleoprotein | -0.0334684 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0333519 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0328637 |
| MT1X | metallothionein 1X | -0.0326872 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0325785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0325363 |
| COG5 | component of oligomeric golgi complex 5 | -0.0325049 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.032426 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0322848 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0320986 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0319332 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0310244 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0306889 |
| COL1A1 | collagen, type I, alpha 1 | -0.0304646 |
| SRP54 | signal recognition particle 54kDa | -0.0302682 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0300949 |
| TFG | TRK-fused gene | -0.0297447 |
| TMEM165 | transmembrane protein 165 | -0.0292873 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0288592 |
| ZNF207 | zinc finger protein 207 | -0.0284684 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0282233 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0281826 |
| RASA2 | RAS p21 protein activator 2 | -0.0281825 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0281177 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0281048 |
| IL6ST | interleukin 6 signal transducer | -0.0280825 |
| MAP4 | microtubule-associated protein 4 | -0.0280763 |
| SEC24A | SEC24 family member A | -0.0280714 |
| WASF2 | WAS protein family, member 2 | -0.0276797 |
| GLG1 | golgi glycoprotein 1 | -0.0275197 |
| POTEF | POTE ankyrin domain family, member F | -0.0274587 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0272516 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0267456 |
| KIF1B | kinesin family member 1B | -0.0265691 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0264888 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0264745 |
| PCBP2 | poly(rC) binding protein 2 | -0.0264664 |
| XPO1 | exportin 1 | -0.0264392 |
| EVI5 | ecotropic viral integration site 5 | -0.0264034 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.02626 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0262438 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0262118 |
| JMJD1C | jumonji domain containing 1C | -0.0260724 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0260632 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0260025 |
| GOLGB1 | golgin B1 | -0.0259909 |
| RTN4 | reticulon 4 | -0.0259338 |
| SRPK2 | SRSF protein kinase 2 | -0.0259157 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0258906 |
| TAOK1 | TAO kinase 1 | -0.0256994 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0255119 |
| RPL35A | ribosomal protein L35a | -0.0255119 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | -0.0255105 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0252812 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0252277 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0251842 |
| SETD5 | SET domain containing 5 | -0.0251178 |
