| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.129938 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0976949 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0920928 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0751381 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0696606 |
| MYO10 | myosin X | 0.066909 |
| LAMB3 | laminin, beta 3 | 0.0666967 |
| ATP13A3 | ATPase type 13A3 | 0.0657757 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0624453 |
| LOX | lysyl oxidase | 0.0602504 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.058006 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0578731 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0574413 |
| STC1 | stanniocalcin 1 | 0.0568462 |
| INHBA | inhibin, beta A | 0.0565978 |
| ANXA2 | annexin A2 | 0.0565425 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0550594 |
| RAI14 | retinoic acid induced 14 | 0.0549322 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0546426 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0495804 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0482222 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0465631 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0463704 |
| CUL3 | cullin 3 | 0.0458535 |
| KIAA1217 | KIAA1217 | 0.0456118 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0455842 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0451755 |
| LOXL2 | lysyl oxidase-like 2 | 0.0451273 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0447398 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0446559 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0441414 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0440533 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0439416 |
| VEGFA | vascular endothelial growth factor A | 0.0437019 |
| TXNRD1 | thioredoxin reductase 1 | 0.0433327 |
| COL5A1 | collagen, type V, alpha 1 | 0.0431186 |
| COPA | coatomer protein complex, subunit alpha | 0.0429137 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0427245 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0425516 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0423324 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0420451 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0411043 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0409448 |
| NDRG1 | N-myc downstream regulated 1 | 0.0397605 |
| NRCAM | neuronal cell adhesion molecule | 0.0392486 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0386515 |
| CLTC | clathrin, heavy chain (Hc) | 0.0385936 |
| TUFT1 | tuftelin 1 | 0.0382769 |
| EFNA5 | ephrin-A5 | 0.0379595 |
| BPTF | bromodomain PHD finger transcription factor | 0.0379366 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0378841 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.037859 |
| PRKCA | protein kinase C, alpha | 0.0376462 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0372914 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0372675 |
| CANX | calnexin | 0.0370455 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0369492 |
| MUC16 | mucin 16, cell surface associated | 0.0368704 |
| EGFR | epidermal growth factor receptor | 0.036052 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0358755 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0358411 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.035836 |
| WDR43 | WD repeat domain 43 | 0.0357025 |
| PCBP3 | poly(rC) binding protein 3 | 0.0349821 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0348912 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0348215 |
| NUMB | numb homolog (Drosophila) | 0.0346012 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0342365 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0339956 |
| FAM13A | family with sequence similarity 13, member A | 0.0339626 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0339058 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0337814 |
| COL5A2 | collagen, type V, alpha 2 | 0.0337543 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0337433 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.033503 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0332625 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0329522 |
| ATOSA | atos homolog A | 0.0328955 |
| RACK1 | receptor for activated C kinase 1 | 0.0328948 |
| ATF3 | activating transcription factor 3 | 0.0326047 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0325687 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.0325404 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0318663 |
| RPL7A | ribosomal protein L7a | 0.0318481 |
| TMEM178B | transmembrane protein 178B | 0.0317468 |
| WDR26 | WD repeat domain 26 | 0.0316112 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0313716 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0311014 |
| TMEM87A | transmembrane protein 87A | 0.0310767 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0310326 |
| ASPH | aspartate beta-hydroxylase | 0.0308672 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0305204 |
| NOP58 | NOP58 ribonucleoprotein | 0.0299339 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0297265 |
| WDR45B | WD repeat domain 45B | 0.0294647 |
| MSI2 | musashi RNA-binding protein 2 | 0.0293221 |
| PRELID2 | PRELI domain containing 2 | 0.0292969 |
| TOP1 | topoisomerase (DNA) I | 0.0292927 |
| FLNB | filamin B, beta | 0.0292148 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0290938 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.116382 |
| PTMA | prothymosin, alpha | -0.0987479 |
| FN1 | fibronectin 1 | -0.0961498 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0936753 |
| VIM | vimentin | -0.0887892 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0875428 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0789239 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0781205 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0763348 |
| RPS19 | ribosomal protein S19 | -0.0717059 |
| RPS6 | ribosomal protein S6 | -0.069116 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0670644 |
| SEPTIN7 | septin 7 | -0.0667448 |
| RTN4 | reticulon 4 | -0.0645525 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.062918 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0615588 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0602955 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0602745 |
| SRPK2 | SRSF protein kinase 2 | -0.0597264 |
| USP33 | ubiquitin specific peptidase 33 | -0.05972 |
| ZNF638 | zinc finger protein 638 | -0.0594389 |
| RLF | rearranged L-myc fusion | -0.0591359 |
| RPLP1 | ribosomal protein, large, P1 | -0.0583156 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0578922 |
| PTK2 | protein tyrosine kinase 2 | -0.0554764 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0551651 |
| POTEF | POTE ankyrin domain family, member F | -0.0537388 |
| INSIG1 | insulin induced gene 1 | -0.0532407 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0530891 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0530097 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0522749 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0520421 |
| RNF145 | ring finger protein 145 | -0.0513558 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0507831 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0507232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0499894 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0494303 |
| RPS5 | ribosomal protein S5 | -0.0493053 |
| GOLGB1 | golgin B1 | -0.0489827 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0489647 |
| RPL8 | ribosomal protein L8 | -0.0489238 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0486148 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0467528 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0460242 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0449536 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0445201 |
| RPS12 | ribosomal protein S12 | -0.0444761 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0436501 |
| KIF5B | kinesin family member 5B | -0.0430757 |
| PLK2 | polo-like kinase 2 | -0.0420801 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0420045 |
| RPS4X | ribosomal protein S4, X-linked | -0.0413903 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0411069 |
| CUL4A | cullin 4A | -0.0409296 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0404994 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0399594 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0396869 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0396289 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | -0.0396244 |
| PDE10A | phosphodiesterase 10A | -0.0394415 |
| ZNF292 | zinc finger protein 292 | -0.0392655 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0387641 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0387611 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | -0.0386993 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0385671 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.038502 |
| HELZ | helicase with zinc finger | -0.0384819 |
| YAP1 | Yes-associated protein 1 | -0.0379554 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.037594 |
| ENO1 | enolase 1, (alpha) | -0.0375518 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0373244 |
| SYPL1 | synaptophysin-like 1 | -0.0367839 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0366912 |
| CDK19 | cyclin-dependent kinase 19 | -0.0365974 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0365954 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0365432 |
| CCNI | cyclin I | -0.0363491 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0362817 |
| WAPL | WAPL cohesin release factor | -0.0358065 |
| AK1 | adenylate kinase 1 | -0.0350578 |
| RPL35 | ribosomal protein L35 | -0.0349915 |
| RUNX1 | runt-related transcription factor 1 | -0.0341292 |
| AFDN | afadin, adherens junction formation factor | -0.0335013 |
| RPL7 | ribosomal protein L7 | -0.0334656 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0333868 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0333593 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0324768 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0324154 |
| GPC6 | glypican 6 | -0.032117 |
| SDCBP | syndecan binding protein (syntenin) | -0.0316137 |
| CNKSR3 | CNKSR family member 3 | -0.0314465 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.031406 |
| TMSB10 | thymosin beta 10 | -0.0313138 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0312852 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.0311242 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0309737 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0307972 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0307786 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0305176 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0304939 |
