| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.0757558 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0290278 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0244713 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0228359 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0219202 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0215534 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0203727 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.020147 |
| PLEC | plectin | 0.0201373 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0197028 |
| SMAD3 | SMAD family member 3 | 0.019023 |
| MKI67 | marker of proliferation Ki-67 | 0.0189414 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.017545 |
| OSMR | oncostatin M receptor | 0.0164359 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0161763 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0158758 |
| PRRC2B | proline-rich coiled-coil 2B | 0.015293 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0143589 |
| PRRC2A | proline-rich coiled-coil 2A | 0.014209 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0139165 |
| ACTN1 | actinin, alpha 1 | 0.0137159 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0136773 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0130953 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0130309 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0130275 |
| KRT18 | keratin 18, type I | 0.0129075 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0128956 |
| AOPEP | aminopeptidase O (putative) | 0.0124321 |
| CTTN | cortactin | 0.0124028 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.0123061 |
| DNMBP | dynamin binding protein | 0.0122707 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0121139 |
| ATP11A | ATPase, class VI, type 11A | 0.0121016 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0120875 |
| CAPRIN2 | caprin family member 2 | 0.0117427 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0116288 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0115911 |
| CCDC200 | coiled-coil domain containing 200 | 0.0113641 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0113213 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0113082 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.011251 |
| LIF | leukemia inhibitory factor | 0.0112387 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0110608 |
| TEAD4 | TEA domain family member 4 | 0.0108415 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0107493 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0107249 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0107143 |
| RAI1 | retinoic acid induced 1 | 0.0106596 |
| ANKRD36 | ankyrin repeat domain 36 | 0.01052 |
| CEP250 | centrosomal protein 250kDa | 0.0104882 |
| PLSCR1 | phospholipid scramblase 1 | 0.0103958 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.010384 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0103721 |
| ANKRD11 | ankyrin repeat domain 11 | 0.010359 |
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.010346 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0101862 |
| RIGI | RNA sensor RIG-I | 0.0101494 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0100901 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.00997669 |
| TMEM41B | transmembrane protein 41B | 0.00983298 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.00981726 |
| RPS18 | ribosomal protein S18 | 0.00978799 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0097796 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00973309 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00952326 |
| CAB39 | calcium binding protein 39 | 0.00952143 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00942819 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.00940493 |
| LOXL2 | lysyl oxidase-like 2 | 0.00935274 |
| PRCC | papillary renal cell carcinoma (translocation-associated) | 0.00929036 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.00926788 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00926348 |
| ITGB5 | integrin, beta 5 | 0.00924573 |
| SNX9 | sorting nexin 9 | 0.00920361 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00880898 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.00878782 |
| CHLSN | cholesin | 0.00876236 |
| MINK1 | misshapen-like kinase 1 | 0.00876009 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.0087598 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.00864635 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00864374 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.00862105 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00851797 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.00850067 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.00844397 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00836794 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00836432 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.00834794 |
| NBDY | negative regulator of P-body association | 0.00831012 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00828115 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00826745 |
| CDK17 | cyclin-dependent kinase 17 | 0.00820745 |
| TCIM | transcriptional and immune response regulator | 0.00819558 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00817206 |
| RESF1 | retroelement silencing factor 1 | 0.0081056 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.00804145 |
| KIAA0319L | KIAA0319-like | 0.00792248 |
| RBBP6 | retinoblastoma binding protein 6 | 0.00786809 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0078095 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.00780201 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.337507 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.168482 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.124369 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101938 |
| VIM | vimentin | -0.0977202 |
| PTMA | prothymosin, alpha | -0.0844739 |
| TMSB10 | thymosin beta 10 | -0.0698491 |
| MCL1 | myeloid cell leukemia 1 | -0.0617953 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0607581 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0607384 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0599856 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0598727 |
| CANX | calnexin | -0.0536659 |
| POTEF | POTE ankyrin domain family, member F | -0.0534358 |
| TPI1 | triosephosphate isomerase 1 | -0.0516595 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.050674 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0457058 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0454341 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0445251 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.043022 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0424231 |
| ENO1 | enolase 1, (alpha) | -0.0420129 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0417912 |
| PKM | pyruvate kinase, muscle | -0.041742 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0411268 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0407515 |
| MORF4L2 | mortality factor 4 like 2 | -0.0397525 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0381602 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0370502 |
| GNAS | GNAS complex locus | -0.0364074 |
| BBX | bobby sox homolog (Drosophila) | -0.035785 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0355379 |
| UBC | ubiquitin C | -0.0352713 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0352047 |
| RPL35A | ribosomal protein L35a | -0.034766 |
| USP34 | ubiquitin specific peptidase 34 | -0.0346534 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0342148 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0337167 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0334302 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.032915 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0321504 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0318737 |
| CALR | calreticulin | -0.0316682 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0315643 |
| HLA-B | major histocompatibility complex, class I, B | -0.0315569 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0315504 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0312311 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0309361 |
| COPA | coatomer protein complex, subunit alpha | -0.0308541 |
| RPL37 | ribosomal protein L37 | -0.0308077 |
| RPS8 | ribosomal protein S8 | -0.0307069 |
| FBXO11 | F-box protein 11 | -0.0306275 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.030608 |
| RSF1 | remodeling and spacing factor 1 | -0.0299985 |
| TPM4 | tropomyosin 4 | -0.0298723 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0298491 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0297774 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0295461 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0293626 |
| RPS15 | ribosomal protein S15 | -0.0293169 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0290714 |
| PCBP2 | poly(rC) binding protein 2 | -0.0289711 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0289404 |
| RPL37A | ribosomal protein L37a | -0.0289339 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0288822 |
| ATXN1 | ataxin 1 | -0.0287264 |
| RPL8 | ribosomal protein L8 | -0.0286121 |
| BPTF | bromodomain PHD finger transcription factor | -0.0284442 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0283873 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0282892 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0279991 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0278504 |
| RPS6 | ribosomal protein S6 | -0.0277579 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0277248 |
| ZNF207 | zinc finger protein 207 | -0.0276962 |
| GPHN | gephyrin | -0.0274022 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0273867 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0269637 |
| FNDC3B | fibronectin type III domain containing 3B | -0.026935 |
| VMP1 | vacuole membrane protein 1 | -0.0267918 |
| ACTG1 | actin gamma 1 | -0.0266057 |
| CLTC | clathrin, heavy chain (Hc) | -0.026536 |
| RPLP1 | ribosomal protein, large, P1 | -0.0264509 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0263865 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0262927 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.026169 |
| RBM39 | RNA binding motif protein 39 | -0.0261689 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0259535 |
| SPAG9 | sperm associated antigen 9 | -0.0258846 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0258762 |
| YBX1 | Y box binding protein 1 | -0.0258322 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0254148 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0250744 |
| PYGL | phosphorylase, glycogen, liver | -0.0250668 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0249352 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0245827 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0244249 |
| GOLGB1 | golgin B1 | -0.0242345 |
| RPLP0 | ribosomal protein, large, P0 | -0.0241903 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.024119 |
