| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.0798299 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0752612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0743099 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0728487 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.069397 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0656917 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0580357 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0567782 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0565948 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0526213 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0500689 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0492274 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0452726 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0449673 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0434843 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0427165 |
| NDRG1 | N-myc downstream regulated 1 | 0.0413583 |
| STC2 | stanniocalcin 2 | 0.0401571 |
| SPAG9 | sperm associated antigen 9 | 0.0400949 |
| CD109 | CD109 molecule | 0.040005 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0398343 |
| EFNA5 | ephrin-A5 | 0.0396835 |
| COPA | coatomer protein complex, subunit alpha | 0.0387162 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0380531 |
| NBAS | neuroblastoma amplified sequence | 0.0369169 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0365638 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0363217 |
| OGA | O-GlcNAcase | 0.036264 |
| ANXA5 | annexin A5 | 0.0356934 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0355266 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0354872 |
| GOLGA4 | golgin A4 | 0.0353047 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0345507 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0336275 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0335572 |
| RTN4 | reticulon 4 | 0.0332542 |
| FAM13A | family with sequence similarity 13, member A | 0.0330849 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0330037 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0329642 |
| MSN | moesin | 0.0326628 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0322281 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0322239 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0320022 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.031957 |
| NUP58 | nucleoporin 58 | 0.0311727 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0310741 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0309394 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0301498 |
| EZR | ezrin | 0.0297735 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0292233 |
| ECT2 | epithelial cell transforming 2 | 0.0291692 |
| WDR45B | WD repeat domain 45B | 0.0290971 |
| HELZ | helicase with zinc finger | 0.0290741 |
| WDR43 | WD repeat domain 43 | 0.0289137 |
| FLNB | filamin B, beta | 0.0284835 |
| TPD52 | tumor protein D52 | 0.0283779 |
| USP34 | ubiquitin specific peptidase 34 | 0.0280138 |
| PTEN | phosphatase and tensin homolog | 0.0277689 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0275001 |
| ATP13A3 | ATPase type 13A3 | 0.0273235 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0271763 |
| FMNL2 | formin-like 2 | 0.0270216 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0266201 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0265083 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0263258 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0260513 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0260425 |
| RUNX1 | runt-related transcription factor 1 | 0.0255828 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0255097 |
| FNIP1 | folliculin interacting protein 1 | 0.0254372 |
| JMJD1C | jumonji domain containing 1C | 0.0253742 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.0248235 |
| CCNL1 | cyclin L1 | 0.0247379 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0244013 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0238076 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0237621 |
| MEF2D | myocyte enhancer factor 2D | 0.0232468 |
| ATXN2 | ataxin 2 | 0.0231917 |
| RBM39 | RNA binding motif protein 39 | 0.0230593 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0229948 |
| LAMA1 | laminin, alpha 1 | 0.0226407 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.022342 |
| EGR1 | early growth response 1 | 0.0223353 |
| RNF145 | ring finger protein 145 | 0.0223156 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0221085 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0219898 |
| VMP1 | vacuole membrane protein 1 | 0.0218278 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0216801 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0215831 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0215354 |
| SEC24A | SEC24 family member A | 0.0213583 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0213172 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0212897 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0212569 |
| CTBP2 | C-terminal binding protein 2 | 0.0209033 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0204263 |
| COG5 | component of oligomeric golgi complex 5 | 0.0203632 |
| VEGFA | vascular endothelial growth factor A | 0.0202023 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0201965 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0201082 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.243226 |
| ASPH | aspartate beta-hydroxylase | -0.144891 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.140881 |
| PDE10A | phosphodiesterase 10A | -0.134212 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.126979 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125041 |
| COL5A2 | collagen, type V, alpha 2 | -0.109049 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.103649 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0880189 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0873182 |
| PCBP3 | poly(rC) binding protein 3 | -0.0859247 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0803056 |
| RPS27A | ribosomal protein S27a | -0.078537 |
| PTMA | prothymosin, alpha | -0.0775589 |
| SMYD3 | SET and MYND domain containing 3 | -0.0730479 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0713047 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0679988 |
| VIM | vimentin | -0.0664164 |
| FTL | ferritin, light polypeptide | -0.0643306 |
| NRCAM | neuronal cell adhesion molecule | -0.0634154 |
| RPL26 | ribosomal protein L26 | -0.0610916 |
| ENO1 | enolase 1, (alpha) | -0.0604748 |
| RPLP1 | ribosomal protein, large, P1 | -0.0600178 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0579425 |
| TMSB10 | thymosin beta 10 | -0.0576979 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0554758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0529748 |
| RPL12 | ribosomal protein L12 | -0.0529627 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0528516 |
| RPS24 | ribosomal protein S24 | -0.0521251 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0508529 |
| PTGR1 | prostaglandin reductase 1 | -0.0508342 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0502477 |
| UBC | ubiquitin C | -0.0502318 |
| RPS8 | ribosomal protein S8 | -0.0467804 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.046085 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0457033 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0442594 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0442322 |
| RPS3 | ribosomal protein S3 | -0.0437879 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0425317 |
| RPL19 | ribosomal protein L19 | -0.0409989 |
| RPS12 | ribosomal protein S12 | -0.0397058 |
| GNAS | GNAS complex locus | -0.0393307 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.038758 |
| RPL38 | ribosomal protein L38 | -0.0385007 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.038424 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0382561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0381882 |
| RPLP0 | ribosomal protein, large, P0 | -0.0366007 |
| CDH13 | cadherin 13 | -0.0363969 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0351447 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0346048 |
| RPL13A | ribosomal protein L13a | -0.034581 |
| RACK1 | receptor for activated C kinase 1 | -0.0341138 |
| AHNAK | AHNAK nucleoprotein | -0.0339067 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0333838 |
| RPL37A | ribosomal protein L37a | -0.033112 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0324365 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0323052 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0321577 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0317202 |
| RPL9 | ribosomal protein L9 | -0.0306931 |
| FN1 | fibronectin 1 | -0.0305688 |
| TXNRD1 | thioredoxin reductase 1 | -0.0304901 |
| RPL31 | ribosomal protein L31 | -0.0303604 |
| AOPEP | aminopeptidase O (putative) | -0.0297834 |
| RPL37 | ribosomal protein L37 | -0.0291675 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0289676 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0289224 |
| RPL4 | ribosomal protein L4 | -0.0286807 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0276429 |
| S100A6 | S100 calcium binding protein A6 | -0.02742 |
| B2M | beta-2-microglobulin | -0.0273651 |
| ACTG1 | actin gamma 1 | -0.0271952 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0268947 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0268611 |
| RTN1 | reticulon 1 | -0.0266973 |
| PALLD | palladin, cytoskeletal associated protein | -0.0263908 |
| SRGN | serglycin | -0.0260897 |
| NCKAP5 | NCK-associated protein 5 | -0.0253972 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0253591 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0251894 |
| RPL23 | ribosomal protein L23 | -0.0250869 |
| PRDX1 | peroxiredoxin 1 | -0.0250497 |
| S100A10 | S100 calcium binding protein A10 | -0.0249255 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0246648 |
| GRAMD1B | GRAM domain containing 1B | -0.0240909 |
| TENM3 | teneurin transmembrane protein 3 | -0.0240677 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0238419 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0237918 |
| MAP7 | microtubule-associated protein 7 | -0.0236042 |
| MT2A | metallothionein 2A | -0.0235945 |
| RPL11 | ribosomal protein L11 | -0.0235265 |
| RAD51B | RAD51 paralog B | -0.0234145 |
| RPS4X | ribosomal protein S4, X-linked | -0.0232652 |
| IER3 | immediate early response 3 | -0.0230066 |
| RPS29 | ribosomal protein S29 | -0.0224914 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221829 |
| SQSTM1 | sequestosome 1 | -0.0217846 |
