| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Piroxicam_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.232019 |
| NDRG1 | N-myc downstream regulated 1 | 0.133509 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.122361 |
| ZNF292 | zinc finger protein 292 | 0.119076 |
| NUP58 | nucleoporin 58 | 0.118702 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.114125 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.110575 |
| MEF2A | myocyte enhancer factor 2A | 0.109843 |
| PARD3 | par-3 family cell polarity regulator | 0.10807 |
| ENO1 | enolase 1, (alpha) | 0.107284 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.101319 |
| RNF145 | ring finger protein 145 | 0.100768 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0978073 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0970011 |
| PTK2 | protein tyrosine kinase 2 | 0.0948284 |
| USP34 | ubiquitin specific peptidase 34 | 0.0892423 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0891632 |
| RORA | RAR-related orphan receptor A | 0.0891021 |
| JMJD1C | jumonji domain containing 1C | 0.0826718 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0815323 |
| RUNX1 | runt-related transcription factor 1 | 0.079478 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0791891 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0747461 |
| GPC6 | glypican 6 | 0.074503 |
| WDR43 | WD repeat domain 43 | 0.0712493 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0708033 |
| VEGFA | vascular endothelial growth factor A | 0.0676557 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0667322 |
| HMGA2 | high mobility group AT-hook 2 | 0.0666234 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0657792 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0627033 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.062403 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0613025 |
| RBM39 | RNA binding motif protein 39 | 0.0610326 |
| PHF3 | PHD finger protein 3 | 0.0592553 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0586011 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0565803 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0561949 |
| CALD1 | caldesmon 1 | 0.0556665 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0553929 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0548535 |
| FAM168A | family with sequence similarity 168, member A | 0.0537551 |
| RPL37A | ribosomal protein L37a | 0.0505374 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0500697 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0481449 |
| LDHA | lactate dehydrogenase A | 0.0474237 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0471393 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0458509 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0452639 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0450482 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0436348 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0435569 |
| RPS21 | ribosomal protein S21 | 0.0405872 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0399935 |
| NAV1 | neuron navigator 1 | 0.0395323 |
| YAP1 | Yes-associated protein 1 | 0.0384683 |
| RPL27A | ribosomal protein L27a | 0.0382409 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0375634 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0354199 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0347929 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0343472 |
| PGK1 | phosphoglycerate kinase 1 | 0.0338837 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0338347 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0324487 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0320211 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0311938 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0309018 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0301381 |
| PRELID2 | PRELI domain containing 2 | 0.0297936 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0291369 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0286107 |
| BRD4 | bromodomain containing 4 | 0.0284927 |
| SMAD3 | SMAD family member 3 | 0.0284537 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0277622 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0273322 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0267431 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0265049 |
| RPS6 | ribosomal protein S6 | 0.0260229 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0259204 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0249678 |
| MTPN | myotrophin | 0.0245941 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0244518 |
| PHIP | pleckstrin homology domain interacting protein | 0.0242252 |
| EGR1 | early growth response 1 | 0.0240925 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0240473 |
| RTN4 | reticulon 4 | 0.0233898 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0221208 |
| RNF213 | ring finger protein 213 | 0.0217766 |
| S100A6 | S100 calcium binding protein A6 | 0.0214925 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.021443 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0212385 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0211051 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0207274 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.020569 |
| USP15 | ubiquitin specific peptidase 15 | 0.0202401 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0198732 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.019772 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0185449 |
| APP | amyloid beta (A4) precursor protein | 0.0182594 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0180359 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.157862 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.147639 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.146546 |
| CANX | calnexin | -0.134426 |
| FNDC3B | fibronectin type III domain containing 3B | -0.131891 |
| EFNA5 | ephrin-A5 | -0.131778 |
| OGA | O-GlcNAcase | -0.125542 |
| ASPH | aspartate beta-hydroxylase | -0.124332 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123887 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.121782 |
| CCNI | cyclin I | -0.118842 |
| TMSB10 | thymosin beta 10 | -0.1185 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.117 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.11619 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.112091 |
| FNDC3A | fibronectin type III domain containing 3A | -0.10968 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.104508 |
| PDE8A | phosphodiesterase 8A | -0.102344 |
| FAM13A | family with sequence similarity 13, member A | -0.0987258 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0940334 |
| GOLGB1 | golgin B1 | -0.0802186 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0787857 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.07453 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0713899 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0693923 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0681337 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.06759 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0660591 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0658823 |
| RPS13 | ribosomal protein S13 | -0.0655747 |
| LAMA4 | laminin, alpha 4 | -0.0653212 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0607836 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0602915 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.060064 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0597279 |
| GOLGA4 | golgin A4 | -0.0566812 |
| RPL8 | ribosomal protein L8 | -0.0554995 |
| PRKCA | protein kinase C, alpha | -0.0550006 |
| MT2A | metallothionein 2A | -0.0542543 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0521056 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0468456 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.04386 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0435795 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0429416 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0425361 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0420886 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0414992 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0402291 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0400216 |
| RIOK3 | RIO kinase 3 | -0.0398269 |
| RPL35A | ribosomal protein L35a | -0.0387641 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0377456 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0355976 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0348843 |
| ANXA2 | annexin A2 | -0.0347921 |
| RPL23 | ribosomal protein L23 | -0.034677 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0340997 |
| TJP1 | tight junction protein 1 | -0.0335375 |
| RAD51B | RAD51 paralog B | -0.0335063 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333836 |
| MED13 | mediator complex subunit 13 | -0.0312625 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0309187 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0308982 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0305604 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0295686 |
| DST | dystonin | -0.0284905 |
| EGFR | epidermal growth factor receptor | -0.0281038 |
| RPL37 | ribosomal protein L37 | -0.0275891 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0274937 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0268784 |
| FTL | ferritin, light polypeptide | -0.0266035 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0266017 |
| HELZ | helicase with zinc finger | -0.0265544 |
| FHIT | fragile histidine triad | -0.0255903 |
| FLNB | filamin B, beta | -0.024774 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0244459 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0233502 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.021811 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0217167 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0208847 |
| VCL | vinculin | -0.0206399 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0203216 |
| TPR | translocated promoter region, nuclear basket protein | -0.0202998 |
| PTMA | prothymosin, alpha | -0.0196189 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0181449 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0177255 |
| PDLIM5 | PDZ and LIM domain 5 | -0.017676 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0176697 |
| POU2F1 | POU class 2 homeobox 1 | -0.0176675 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0171333 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0170813 |
| NBAS | neuroblastoma amplified sequence | -0.0168501 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0167906 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0162641 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0159227 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.015837 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0158129 |
| DSTN | destrin (actin depolymerizing factor) | -0.0156649 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0150171 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0137657 |
