| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Piroxicam_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NTM | neurotrimin | 0.110233 |
| MKI67 | marker of proliferation Ki-67 | 0.0563376 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0562524 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0489052 |
| ANXA1 | annexin A1 | 0.043993 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0428274 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0417026 |
| RACK1 | receptor for activated C kinase 1 | 0.0414199 |
| PFN1 | profilin 1 | 0.0413417 |
| RPL36 | ribosomal protein L36 | 0.0393445 |
| RPS12 | ribosomal protein S12 | 0.0385522 |
| RIGI | RNA sensor RIG-I | 0.0372011 |
| CCN2 | cellular communication network factor 2 | 0.0364986 |
| RPS6 | ribosomal protein S6 | 0.0332237 |
| VEGFA | vascular endothelial growth factor A | 0.0325024 |
| CENPF | centromere protein F, 350/400kDa | 0.0316541 |
| TENM2 | teneurin transmembrane protein 2 | 0.0314002 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0310082 |
| PRTG | protogenin | 0.0296329 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0290528 |
| PEG10 | paternally expressed 10 | 0.0286793 |
| RPS2 | ribosomal protein S2 | 0.0286427 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0283537 |
| MSN | moesin | 0.0282345 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0281187 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0280491 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0272529 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0270127 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0268947 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.026769 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0267623 |
| SNX3 | sorting nexin 3 | 0.0263888 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0263355 |
| RPS3 | ribosomal protein S3 | 0.0253025 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0247901 |
| RPL23 | ribosomal protein L23 | 0.0247876 |
| FGF13 | fibroblast growth factor 13 | 0.0247166 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0243924 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0241616 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0237437 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0233749 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0229014 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0227065 |
| CBX5 | chromobox homolog 5 | 0.0226491 |
| CALR | calreticulin | 0.0223843 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0222939 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0221847 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0220975 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0220436 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0219658 |
| CTSB | cathepsin B | 0.0219246 |
| FAT1 | FAT atypical cadherin 1 | 0.0218449 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0216967 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0212707 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0210393 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | 0.0201922 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | 0.0201902 |
| TMSB10 | thymosin beta 10 | 0.0199797 |
| TGFB2 | transforming growth factor, beta 2 | 0.0198537 |
| WWC2 | WW and C2 domain containing 2 | 0.0197957 |
| RPL31 | ribosomal protein L31 | 0.0197565 |
| H1-0 | H1.0 linker histone | 0.019654 |
| SET | SET nuclear proto-oncogene | 0.0195561 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0195126 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0194984 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0193547 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0191243 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0190193 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0189944 |
| RPS10 | ribosomal protein S10 | 0.0189763 |
| FTL | ferritin, light polypeptide | 0.0188882 |
| PLPP1 | phospholipid phosphatase 1 | 0.0188736 |
| SLK | STE20-like kinase | 0.0186801 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0186551 |
| RPL3 | ribosomal protein L3 | 0.0185925 |
| WASF2 | WAS protein family, member 2 | 0.0184349 |
| FST | follistatin | 0.017924 |
| RPS14 | ribosomal protein S14 | 0.0177715 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0177537 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0174493 |
| RPL18 | ribosomal protein L18 | 0.0174376 |
| NGFR | nerve growth factor receptor | 0.0173566 |
| PRRC2B | proline-rich coiled-coil 2B | 0.017244 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0172434 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0168432 |
| PNN | pinin, desmosome associated protein | 0.0167986 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0167793 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0167249 |
| PLCG1 | phospholipase C, gamma 1 | 0.0165665 |
| TUBA1B | tubulin, alpha 1b | 0.0164793 |
| PCDH18 | protocadherin 18 | 0.0164321 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.0163825 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0162785 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0162674 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.0162421 |
| NUP188 | nucleoporin 188kDa | 0.0162336 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0161629 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0160773 |
| RPS7 | ribosomal protein S7 | 0.0158491 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0158252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.152908 |
| ZNF292 | zinc finger protein 292 | -0.096003 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0914138 |
| GPC3 | glypican 3 | -0.0858838 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0854277 |
| SPAG9 | sperm associated antigen 9 | -0.076994 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0768787 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0711367 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0603297 |
| MED13L | mediator complex subunit 13-like | -0.0595671 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0586315 |
| TSC22D2 | TSC22 domain family, member 2 | -0.05748 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0563219 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0554819 |
| VIM | vimentin | -0.0550844 |
| JMJD1C | jumonji domain containing 1C | -0.0534129 |
| TMSB4X | thymosin beta 4, X-linked | -0.049994 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0488322 |
| SYT1 | synaptotagmin I | -0.0485631 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0479269 |
| PHIP | pleckstrin homology domain interacting protein | -0.0465126 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0446075 |
| THBS1 | thrombospondin 1 | -0.0425873 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0423659 |
| ITGAV | integrin, alpha V | -0.0413145 |
| SMYD3 | SET and MYND domain containing 3 | -0.0408994 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0408717 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0405056 |
| RPS16 | ribosomal protein S16 | -0.0396098 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0384852 |
| COL3A1 | collagen, type III, alpha 1 | -0.0376092 |
| AHNAK | AHNAK nucleoprotein | -0.0371142 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0368326 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0365044 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0363921 |
| DSTN | destrin (actin depolymerizing factor) | -0.0357806 |
| FBXO11 | F-box protein 11 | -0.0356454 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0355747 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0346055 |
| RHEB | Ras homolog enriched in brain | -0.0345451 |
| TXNRD1 | thioredoxin reductase 1 | -0.0344855 |
| GNAS | GNAS complex locus | -0.0343383 |
| GLG1 | golgi glycoprotein 1 | -0.0340821 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0340161 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0338071 |
| RBM39 | RNA binding motif protein 39 | -0.0336585 |
| DENND4C | DENN/MADD domain containing 4C | -0.0335458 |
| METAP2 | methionyl aminopeptidase 2 | -0.0335405 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0333543 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0332846 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330702 |
| SEPTIN7 | septin 7 | -0.0328779 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0326029 |
| EMP1 | epithelial membrane protein 1 | -0.0323096 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0321182 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0320134 |
| USP34 | ubiquitin specific peptidase 34 | -0.0317862 |
| COG5 | component of oligomeric golgi complex 5 | -0.0316209 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0316014 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0315981 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0313641 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.031302 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.031253 |
| NF1 | neurofibromin 1 | -0.0309823 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0306101 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.030363 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0303118 |
| RLF | rearranged L-myc fusion | -0.0299302 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0298326 |
| ZFR | zinc finger RNA binding protein | -0.0294849 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0293391 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0287754 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0287166 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0287102 |
| ABI2 | abl-interactor 2 | -0.0286824 |
| PARD3 | par-3 family cell polarity regulator | -0.0284939 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0284051 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.028401 |
| ZNF207 | zinc finger protein 207 | -0.0283613 |
| KIF5B | kinesin family member 5B | -0.0283479 |
| ANKRD12 | ankyrin repeat domain 12 | -0.028217 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0280851 |
| CADM2 | cell adhesion molecule 2 | -0.0279674 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0277722 |
| COL1A2 | collagen, type I, alpha 2 | -0.0273232 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0273108 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0273048 |
| MED13 | mediator complex subunit 13 | -0.0272292 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.026911 |
| DST | dystonin | -0.0268648 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0266012 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0264517 |
| TMEM123 | transmembrane protein 123 | -0.0263488 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0263307 |
| EVI5 | ecotropic viral integration site 5 | -0.0262789 |
| VMP1 | vacuole membrane protein 1 | -0.0259427 |
| STAG2 | stromal antigen 2 | -0.0259303 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0259048 |
| XPO1 | exportin 1 | -0.0256927 |
| RHOA | ras homolog family member A | -0.0256594 |
