| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.156125 |
| PTMA | prothymosin, alpha | 0.144688 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.127976 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.123432 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.106351 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0861566 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0806055 |
| PLXNA1 | plexin A1 | 0.0666657 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.061711 |
| RPS3 | ribosomal protein S3 | 0.0583178 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0562819 |
| FLNB | filamin B, beta | 0.0554229 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0535971 |
| DUSP4 | dual specificity phosphatase 4 | 0.0534318 |
| VEGFA | vascular endothelial growth factor A | 0.0524093 |
| EGFR | epidermal growth factor receptor | 0.0520518 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0508262 |
| GLI2 | GLI family zinc finger 2 | 0.0490885 |
| RACK1 | receptor for activated C kinase 1 | 0.0477165 |
| ACTG1 | actin gamma 1 | 0.0476226 |
| GSE1 | Gse1 coiled-coil protein | 0.0463851 |
| ANXA1 | annexin A1 | 0.0463348 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0451726 |
| FAT1 | FAT atypical cadherin 1 | 0.0435746 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0433737 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0433043 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0432819 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0421683 |
| GOLGA4 | golgin A4 | 0.040544 |
| SET | SET nuclear proto-oncogene | 0.0404461 |
| MKI67 | marker of proliferation Ki-67 | 0.0398843 |
| FBLN2 | fibulin 2 | 0.0387437 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0382453 |
| RPL13A | ribosomal protein L13a | 0.038161 |
| TMSB4X | thymosin beta 4, X-linked | 0.0377496 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0376771 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0373401 |
| RPL3 | ribosomal protein L3 | 0.0359418 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0355164 |
| RPS6 | ribosomal protein S6 | 0.0351328 |
| RPL7A | ribosomal protein L7a | 0.0346213 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0340402 |
| ATN1 | atrophin 1 | 0.033752 |
| PHF3 | PHD finger protein 3 | 0.0317828 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0309544 |
| LDHA | lactate dehydrogenase A | 0.0306286 |
| MYOF | myoferlin | 0.0305761 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292854 |
| SLC41A1 | solute carrier family 41 (magnesium transporter), member 1 | 0.0291001 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.028899 |
| AMOTL2 | angiomotin like 2 | 0.0286234 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0284677 |
| TRIM44 | tripartite motif containing 44 | 0.0282677 |
| MATR3 | matrin 3 | 0.0280009 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0279231 |
| TMEM14C | transmembrane protein 14C | 0.0277195 |
| RRBP1 | ribosome binding protein 1 | 0.0277077 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0275913 |
| RPS18 | ribosomal protein S18 | 0.0273234 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0272201 |
| LOXL3 | lysyl oxidase-like 3 | 0.0270853 |
| PIAS3 | protein inhibitor of activated STAT, 3 | 0.0269945 |
| DENND1A | DENN/MADD domain containing 1A | 0.0267829 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0256454 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0253846 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0252816 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0251095 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0250132 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0249888 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | 0.0249816 |
| PRRC2B | proline-rich coiled-coil 2B | 0.024905 |
| EZR | ezrin | 0.0247553 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0247186 |
| RPL11 | ribosomal protein L11 | 0.0246786 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0246452 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0245291 |
| RPS12 | ribosomal protein S12 | 0.0244143 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0243617 |
| RPL36 | ribosomal protein L36 | 0.0241665 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0240765 |
| PYGB | phosphorylase, glycogen; brain | 0.024024 |
| RPL37A | ribosomal protein L37a | 0.023783 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0236641 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0234386 |
| SQSTM1 | sequestosome 1 | 0.0234006 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0232038 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0231732 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.023158 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0230554 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0227688 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0226534 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0223146 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0222536 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0220291 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0219604 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0218543 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0218359 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0218341 |
| HDGF | hepatoma-derived growth factor | 0.0217701 |
| CALR | calreticulin | 0.0216561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167535 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.107155 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0918249 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0879008 |
| RHOA | ras homolog family member A | -0.0748253 |
| AHNAK | AHNAK nucleoprotein | -0.0719355 |
| ZNF292 | zinc finger protein 292 | -0.0692983 |
| XPO1 | exportin 1 | -0.0685909 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0612305 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0609003 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0574421 |
| CANX | calnexin | -0.0574052 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0536102 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.052149 |
| USP34 | ubiquitin specific peptidase 34 | -0.0514896 |
| POTEF | POTE ankyrin domain family, member F | -0.0506147 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0503174 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0497436 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0490346 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.048848 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0481755 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0478558 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0478129 |
| NUP58 | nucleoporin 58 | -0.047798 |
| TXNIP | thioredoxin interacting protein | -0.0469666 |
| SEPTIN7 | septin 7 | -0.0468385 |
| VCL | vinculin | -0.0459267 |
| PGK1 | phosphoglycerate kinase 1 | -0.0454735 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0450731 |
| JMJD1C | jumonji domain containing 1C | -0.0448088 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0447194 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0441521 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0434336 |
| NCKAP1 | NCK-associated protein 1 | -0.0433792 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0429602 |
| SETD5 | SET domain containing 5 | -0.0426832 |
| ZNF644 | zinc finger protein 644 | -0.0426829 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0411613 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0405408 |
| RPS24 | ribosomal protein S24 | -0.0403836 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0401965 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0399543 |
| TAOK1 | TAO kinase 1 | -0.0399174 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0399024 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0394179 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0392785 |
| RYBP | RING1 and YY1 binding protein | -0.0387681 |
| MED13L | mediator complex subunit 13-like | -0.0386159 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0384182 |
| S100A6 | S100 calcium binding protein A6 | -0.0383142 |
| SRP54 | signal recognition particle 54kDa | -0.0378654 |
| RTN4 | reticulon 4 | -0.03783 |
| NBEA | neurobeachin | -0.03721 |
| GNAS | GNAS complex locus | -0.0362563 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0359926 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0359518 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0355829 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0354164 |
| RBM39 | RNA binding motif protein 39 | -0.0350636 |
| PRPF38B | pre-mRNA processing factor 38B | -0.0347211 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0345655 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0343574 |
| EXOC6B | exocyst complex component 6B | -0.0340178 |
| RPL27A | ribosomal protein L27a | -0.0339219 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0337365 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0334946 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0333308 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0332779 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0330378 |
| RPLP0 | ribosomal protein, large, P0 | -0.0327664 |
| PKM | pyruvate kinase, muscle | -0.0327073 |
| CDC73 | cell division cycle 73 | -0.0325591 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0321366 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0318437 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0317556 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0317076 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0315625 |
| YAP1 | Yes-associated protein 1 | -0.0308818 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0308598 |
| CCNL1 | cyclin L1 | -0.0308566 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0306805 |
| FBXO11 | F-box protein 11 | -0.0306362 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0305552 |
| ZNF207 | zinc finger protein 207 | -0.0304532 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.030267 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0302446 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0300639 |
| UBC | ubiquitin C | -0.02998 |
| SNX14 | sorting nexin 14 | -0.0297968 |
| MORF4L2 | mortality factor 4 like 2 | -0.0297428 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0295521 |
| EVI5 | ecotropic viral integration site 5 | -0.0295075 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0294869 |
| PCM1 | pericentriolar material 1 | -0.0293684 |
| FOXP1 | forkhead box P1 | -0.0288311 |
| OGA | O-GlcNAcase | -0.0284693 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0283143 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0282708 |
| MED13 | mediator complex subunit 13 | -0.0281729 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0281477 |