| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Piroxicam_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.147955 |
| COL6A3 | collagen, type VI, alpha 3 | 0.124493 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0880006 |
| HLA-B | major histocompatibility complex, class I, B | 0.0857668 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0746015 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.06574 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0615019 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0608687 |
| NDRG1 | N-myc downstream regulated 1 | 0.0600652 |
| IGF2 | insulin-like growth factor 2 | 0.0577774 |
| FAM13A | family with sequence similarity 13, member A | 0.0565307 |
| COL1A1 | collagen, type I, alpha 1 | 0.0557192 |
| FTL | ferritin, light polypeptide | 0.055254 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0541961 |
| MT1X | metallothionein 1X | 0.0510909 |
| SFTPA2 | surfactant protein A2 | 0.0507785 |
| TMSB10 | thymosin beta 10 | 0.0496913 |
| COL5A1 | collagen, type V, alpha 1 | 0.0489093 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0473505 |
| TMEM263 | transmembrane protein 263 | 0.0458039 |
| ARRDC3 | arrestin domain containing 3 | 0.0453258 |
| CD44 | CD44 molecule (Indian blood group) | 0.0450135 |
| ZNF292 | zinc finger protein 292 | 0.0445623 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0443953 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.0440137 |
| LOXL2 | lysyl oxidase-like 2 | 0.0432267 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0430376 |
| FLNA | filamin A, alpha | 0.0430229 |
| ATP13A3 | ATPase type 13A3 | 0.0428873 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0392697 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0380207 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0379494 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0379199 |
| YTHDC1 | YTH domain containing 1 | 0.0375163 |
| ZNF395 | zinc finger protein 395 | 0.0363717 |
| PGK1 | phosphoglycerate kinase 1 | 0.0359952 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0359595 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0356523 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0356345 |
| PTK2 | protein tyrosine kinase 2 | 0.0348798 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0336618 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0329096 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0321935 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0321789 |
| SMYD3 | SET and MYND domain containing 3 | 0.0320652 |
| ANXA6 | annexin A6 | 0.0319474 |
| RUNX1 | runt-related transcription factor 1 | 0.0318678 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.031811 |
| LDHA | lactate dehydrogenase A | 0.0313452 |
| SEC61G | Sec61 gamma subunit | 0.0312262 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0307026 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0306895 |
| RPS3 | ribosomal protein S3 | 0.0302097 |
| GOLGB1 | golgin B1 | 0.03014 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.029677 |
| HOMER2 | homer scaffolding protein 2 | 0.0294094 |
| COL6A2 | collagen, type VI, alpha 2 | 0.029081 |
| C1D | C1D nuclear receptor corepressor | 0.0290152 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0287845 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | 0.0286887 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0286265 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0284481 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0280245 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0278499 |
| SET | SET nuclear proto-oncogene | 0.0277862 |
| C1S | complement component 1, s subcomponent | 0.0276495 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0274118 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0272406 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.026926 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0267736 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0266594 |
| CSNK1E | casein kinase 1, epsilon | 0.0266162 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0260644 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0257678 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0256649 |
| CTSB | cathepsin B | 0.0256125 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0255817 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0255357 |
| LMNA | lamin A/C | 0.0255209 |
| PTMA | prothymosin, alpha | 0.0254877 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0253125 |
| TMSB4X | thymosin beta 4, X-linked | 0.0251023 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.0248808 |
| SEC24C | SEC24 family member C | 0.0248373 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0246776 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0243935 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0243927 |
| RRBP1 | ribosome binding protein 1 | 0.0243879 |
| CLSTN1 | calsyntenin 1 | 0.0243343 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0242907 |
| BMP1 | bone morphogenetic protein 1 | 0.0241551 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0238258 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.0237851 |
| RPLP2 | ribosomal protein, large, P2 | 0.0237724 |
| ACVR1 | activin A receptor, type I | 0.0237524 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0237185 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0237037 |
| CADM1 | cell adhesion molecule 1 | 0.0236063 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0234629 |
| RPL5 | ribosomal protein L5 | 0.0232878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.179367 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.131321 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0831826 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0830632 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0742366 |
| VCL | vinculin | -0.073384 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0733248 |
| STC1 | stanniocalcin 1 | -0.0729621 |
| LOX | lysyl oxidase | -0.0659466 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0627058 |
| POTEF | POTE ankyrin domain family, member F | -0.0623438 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0622157 |
| HMGA2 | high mobility group AT-hook 2 | -0.0572003 |
| ASPH | aspartate beta-hydroxylase | -0.0511125 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0505169 |
| ADM | adrenomedullin | -0.0464403 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0451791 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0449709 |
| CCNI | cyclin I | -0.0446594 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0439762 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0422762 |
| EXT1 | exostosin glycosyltransferase 1 | -0.042123 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0420657 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0419999 |
| TNS3 | tensin 3 | -0.0417076 |
| RTN4 | reticulon 4 | -0.0415634 |
| TPM1 | tropomyosin 1 (alpha) | -0.0409414 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0405496 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0405313 |
| B2M | beta-2-microglobulin | -0.039693 |
| CDK6 | cyclin-dependent kinase 6 | -0.0393283 |
| CLIC4 | chloride intracellular channel 4 | -0.0391713 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0390916 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0390816 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0383158 |
| SDC4 | syndecan 4 | -0.0382885 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0379714 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0379413 |
| ECE1 | endothelin converting enzyme 1 | -0.037563 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0375575 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0371869 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0371428 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0367602 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0366492 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0365187 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0362943 |
| AHNAK | AHNAK nucleoprotein | -0.0356454 |
| CBX3 | chromobox homolog 3 | -0.0355427 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.035346 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0347477 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0346386 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0345581 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0342922 |
| IL6ST | interleukin 6 signal transducer | -0.0340604 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0336846 |
| TXNRD1 | thioredoxin reductase 1 | -0.0335864 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -0.0332922 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0331133 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0329836 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0326305 |
| TPM4 | tropomyosin 4 | -0.0318468 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | -0.0316403 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0312404 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0310583 |
| SPAG9 | sperm associated antigen 9 | -0.0305993 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0303024 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0301078 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0298518 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0297826 |
| S100A10 | S100 calcium binding protein A10 | -0.0297201 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0296481 |
| RPL19 | ribosomal protein L19 | -0.0295166 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0294535 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0294266 |
| NABP1 | nucleic acid binding protein 1 | -0.0291127 |
| RHOA | ras homolog family member A | -0.0287062 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0283996 |
| KYNU | kynureninase | -0.0279169 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0278483 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0277873 |
| GLIS3 | GLIS family zinc finger 3 | -0.0276973 |
| VIM | vimentin | -0.0276767 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0274855 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0274662 |
| RPS16 | ribosomal protein S16 | -0.0274481 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.027126 |
| SRP54 | signal recognition particle 54kDa | -0.0269477 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0266927 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0264339 |
| EGFR | epidermal growth factor receptor | -0.0263781 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0262088 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0260042 |
| CCNK | cyclin K | -0.0259159 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0259051 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0258887 |
| TMEM87A | transmembrane protein 87A | -0.0258242 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0257676 |
| TFG | TRK-fused gene | -0.0254928 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0254584 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0254016 |
