| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Piroxicam perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Piroxicam_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.0959788 |
| LDHA | lactate dehydrogenase A | 0.0914505 |
| MATR3 | matrin 3 | 0.0552588 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.052342 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0503382 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0490853 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0486847 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0478079 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0476037 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.047445 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0465877 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0459228 |
| ARRDC3 | arrestin domain containing 3 | 0.0447687 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0430926 |
| CEP250 | centrosomal protein 250kDa | 0.0429853 |
| FLNA | filamin A, alpha | 0.0404799 |
| IGF2 | insulin-like growth factor 2 | 0.0386706 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0384933 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.037722 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0375527 |
| SMAD3 | SMAD family member 3 | 0.0372514 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0369818 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0365466 |
| VEGFA | vascular endothelial growth factor A | 0.0364122 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0354797 |
| SAFB2 | scaffold attachment factor B2 | 0.034792 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0346192 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0344937 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0331544 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0328138 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0324907 |
| QKI | QKI, KH domain containing, RNA binding | 0.0318858 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0317387 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0317165 |
| CAPRIN2 | caprin family member 2 | 0.0308652 |
| RACK1 | receptor for activated C kinase 1 | 0.0305405 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0303658 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0302586 |
| TMEM263 | transmembrane protein 263 | 0.0296924 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0296403 |
| MSN | moesin | 0.0292528 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0292102 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0278505 |
| KIF5B | kinesin family member 5B | 0.0276894 |
| ATP11A | ATPase, class VI, type 11A | 0.0272102 |
| CUL4B | cullin 4B | 0.0268673 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0267385 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0265209 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.026015 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0257021 |
| DUSP12 | dual specificity phosphatase 12 | 0.0254814 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0249399 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0247657 |
| PTMA | prothymosin, alpha | 0.0246878 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0246233 |
| INTS13 | integrator complex subunit 13 | 0.0245809 |
| KLF6 | Kruppel-like factor 6 | 0.0245237 |
| ACTN1 | actinin, alpha 1 | 0.0243318 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0239605 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0237473 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.023672 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.023657 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0235636 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0233475 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.02332 |
| MINK1 | misshapen-like kinase 1 | 0.0233021 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0232812 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.023187 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0231423 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0228784 |
| UBAP2L | ubiquitin associated protein 2-like | 0.022808 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0227781 |
| PYGL | phosphorylase, glycogen, liver | 0.0225814 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0223037 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0222236 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.022164 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0221063 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0220918 |
| RPS18 | ribosomal protein S18 | 0.0220183 |
| RASA3 | RAS p21 protein activator 3 | 0.0219735 |
| RPL3 | ribosomal protein L3 | 0.0218645 |
| XPOT | exportin, tRNA | 0.0218508 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0217953 |
| BRD2 | bromodomain containing 2 | 0.0216155 |
| ANXA1 | annexin A1 | 0.0215795 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0215017 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0215004 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0212737 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0211779 |
| WDR33 | WD repeat domain 33 | 0.0211763 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0211559 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0210404 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0210196 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0209074 |
| PAPOLA | poly(A) polymerase alpha | 0.020804 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0206949 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0206428 |
| STX18 | syntaxin 18 | 0.0206425 |
| UBQLN1 | ubiquilin 1 | 0.0205139 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0204008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.125326 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0798416 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0785115 |
| RPLP1 | ribosomal protein, large, P1 | -0.0597183 |
| AHNAK | AHNAK nucleoprotein | -0.0583031 |
| VCL | vinculin | -0.0544284 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0543047 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0541712 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0498304 |
| TMEM123 | transmembrane protein 123 | -0.0495337 |
| POTEF | POTE ankyrin domain family, member F | -0.0460509 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0460017 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0448103 |
| TAOK1 | TAO kinase 1 | -0.0426665 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.042384 |
| BPTF | bromodomain PHD finger transcription factor | -0.0421066 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0416274 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0403236 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.039984 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0394749 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039424 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0389838 |
| MT2A | metallothionein 2A | -0.0384805 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0383051 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0380062 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0379666 |
| RPLP0 | ribosomal protein, large, P0 | -0.0376752 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.037485 |
| PRELID2 | PRELI domain containing 2 | -0.0372487 |
| SEPTIN7 | septin 7 | -0.0371235 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0357071 |
| GLG1 | golgi glycoprotein 1 | -0.0356773 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0351933 |
| FBXO11 | F-box protein 11 | -0.0347375 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0345887 |
| ERBIN | erbb2 interacting protein | -0.0344826 |
| PHF20 | PHD finger protein 20 | -0.0344771 |
| DEK | DEK proto-oncogene | -0.0340791 |
| SP100 | SP100 nuclear antigen | -0.033886 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0338336 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0336696 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.033629 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0335075 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0331289 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0330296 |
| RTN4 | reticulon 4 | -0.0329582 |
| ZNF609 | zinc finger protein 609 | -0.0328165 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0326387 |
| PCNX2 | pecanex 2 | -0.0324926 |
| COG5 | component of oligomeric golgi complex 5 | -0.0322171 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0320223 |
| SVIL | supervillin | -0.0309228 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0307439 |
| DST | dystonin | -0.0304431 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0302814 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0299245 |
| NBEA | neurobeachin | -0.02992 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0298734 |
| WDR45B | WD repeat domain 45B | -0.0296132 |
| PRR11 | proline rich 11 | -0.0292897 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0292409 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0292293 |
| TUT4 | terminal uridylyl transferase 4 | -0.0291752 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0291744 |
| PTK2 | protein tyrosine kinase 2 | -0.0290267 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0287512 |
| TXNRD1 | thioredoxin reductase 1 | -0.0286913 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0285129 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0283755 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0283602 |
| HMGA2 | high mobility group AT-hook 2 | -0.0282659 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0279204 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0277512 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0274066 |
| LDHB | lactate dehydrogenase B | -0.0273016 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0272649 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.02726 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0272513 |
| PERP | PERP, TP53 apoptosis effector | -0.027012 |
| RPL32 | ribosomal protein L32 | -0.0268112 |
| CDCP1 | CUB domain containing protein 1 | -0.0267511 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0266347 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0265589 |
| PDE10A | phosphodiesterase 10A | -0.0264665 |
| JMJD1C | jumonji domain containing 1C | -0.0263873 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0263487 |
| USP34 | ubiquitin specific peptidase 34 | -0.0263475 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0262117 |
| H3-3B | H3.3 histone B | -0.0261701 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0260889 |
| FAM76B | family with sequence similarity 76, member B | -0.0260875 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0260746 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0259741 |
| PRKCA | protein kinase C, alpha | -0.0258129 |
| HELZ | helicase with zinc finger | -0.0256437 |
| MYO9A | myosin IXA | -0.025628 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0255798 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0255278 |
| TES | testin LIM domain protein | -0.0255252 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.025418 |
