| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0740135 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0671517 |
| CPOX | coproporphyrinogen oxidase | 0.0570092 |
| ANXA1 | annexin A1 | 0.0510644 |
| HDAC9 | histone deacetylase 9 | 0.0467605 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0445621 |
| KLF6 | Kruppel-like factor 6 | 0.0405928 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.037998 |
| EPHA5 | EPH receptor A5 | 0.0354323 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0347094 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0339082 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.032454 |
| GPR15 | G protein-coupled receptor 15 | 0.0293902 |
| RPL13A | ribosomal protein L13a | 0.0286951 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.028586 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0251687 |
| RNF145 | ring finger protein 145 | 0.0243667 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0243356 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0242813 |
| EZR | ezrin | 0.023957 |
| SPAG9 | sperm associated antigen 9 | 0.0238372 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0226689 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0226582 |
| TRIM33 | tripartite motif containing 33 | 0.0219684 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0218858 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0217794 |
| PTMA | prothymosin, alpha | 0.0215376 |
| PTMS | parathymosin | 0.021514 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0214437 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0198292 |
| PDGFC | platelet derived growth factor C | 0.019558 |
| RPS3 | ribosomal protein S3 | 0.0194686 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0191316 |
| RPSA | ribosomal protein SA | 0.0189836 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0186955 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0185721 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.018378 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0179607 |
| MGAT4C | MGAT4 family, member C | 0.0178635 |
| CALR | calreticulin | 0.0178268 |
| TFG | TRK-fused gene | 0.017759 |
| RPL37A | ribosomal protein L37a | 0.0176565 |
| TXNRD1 | thioredoxin reductase 1 | 0.017494 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0174381 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0171408 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | 0.0171046 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.016871 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0168176 |
| RPL36AL | ribosomal protein L36a-like | 0.016621 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0164854 |
| RHOB | ras homolog family member B | 0.016455 |
| NCKAP1 | NCK-associated protein 1 | 0.0162809 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0162326 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0161939 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0159353 |
| MATR3 | matrin 3 | 0.015921 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | 0.0158267 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.015544 |
| RPL3 | ribosomal protein L3 | 0.0154879 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0154807 |
| RPL23 | ribosomal protein L23 | 0.0153843 |
| SVIL | supervillin | 0.0152764 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.0147707 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0147123 |
| ATP5MK | ATP synthase membrane subunit k | 0.0146753 |
| USP24 | ubiquitin specific peptidase 24 | 0.014631 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0145794 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0145267 |
| RPS15A | ribosomal protein S15a | 0.0145222 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0142857 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0142768 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0141163 |
| CLDND1 | claudin domain containing 1 | 0.0141049 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0140703 |
| KMT5B | lysine methyltransferase 5B | 0.0139215 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0138349 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.013823 |
| RPS7 | ribosomal protein S7 | 0.0138077 |
| HDGF | hepatoma-derived growth factor | 0.013803 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0138008 |
| TMEM117 | transmembrane protein 117 | 0.0136357 |
| SNX27 | sorting nexin family member 27 | 0.0133695 |
| RPL26 | ribosomal protein L26 | 0.0133089 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0132585 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0132224 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.01297 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.0129514 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0127841 |
| RHOQ | ras homolog family member Q | 0.0126932 |
| SHTN1 | shootin 1 | 0.0126766 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0126065 |
| VDAC3 | voltage-dependent anion channel 3 | 0.0125013 |
| UBQLN1 | ubiquilin 1 | 0.0124829 |
| CFAP73 | cilia and flagella associated protein 73 | 0.0124779 |
| ATP9B | ATPase, class II, type 9B | 0.012466 |
| KLRC4 | killer cell lectin-like receptor subfamily C, member 4 | 0.0124284 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0123094 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0121383 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0121338 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0119799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.425286 |
| VIM | vimentin | -0.230079 |
| AREG | amphiregulin | -0.11563 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0937137 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0889354 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0845405 |
| ACTG1 | actin gamma 1 | -0.0808411 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.079991 |
| PCDH7 | protocadherin 7 | -0.0721788 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0718605 |
| VMP1 | vacuole membrane protein 1 | -0.0713649 |
| EHBP1 | EH domain binding protein 1 | -0.0706924 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0702664 |
| NEBL | nebulette | -0.0694354 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0679866 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0660738 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0655091 |
| MMP12 | matrix metallopeptidase 12 | -0.0646235 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0642569 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0638012 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0611995 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0586464 |
| PFN1 | profilin 1 | -0.0582953 |
| RASAL2 | RAS protein activator like 2 | -0.0569595 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0567378 |
| POTEF | POTE ankyrin domain family, member F | -0.0566288 |
| TMEM123 | transmembrane protein 123 | -0.056114 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0551058 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0548889 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0546747 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0546265 |
| DST | dystonin | -0.0535563 |
| NLGN1 | neuroligin 1 | -0.0530521 |
| RRM2 | ribonucleotide reductase M2 | -0.0510669 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0509351 |
| TUBA1B | tubulin, alpha 1b | -0.0507268 |
| EGR1 | early growth response 1 | -0.05054 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0504528 |
| PCBP2 | poly(rC) binding protein 2 | -0.0495761 |
| CCN2 | cellular communication network factor 2 | -0.0491082 |
| BCHE | butyrylcholinesterase | -0.0488725 |
| CMIP | c-Maf inducing protein | -0.0485185 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0472414 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.046709 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.046372 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0444413 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0440217 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0438302 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0438279 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0427208 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0422965 |
| LDHA | lactate dehydrogenase A | -0.0414113 |
| ASPH | aspartate beta-hydroxylase | -0.0411373 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0411355 |
| CCND1 | cyclin D1 | -0.0409432 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0408853 |
| ZNF804A | zinc finger protein 804A | -0.0380009 |
| GPHN | gephyrin | -0.0372867 |
| EDARADD | EDAR-associated death domain | -0.0370463 |
| BPTF | bromodomain PHD finger transcription factor | -0.0362454 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0355313 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0350586 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0350185 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0348391 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0346065 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.033708 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0333797 |
| CEP350 | centrosomal protein 350kDa | -0.0332729 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0332663 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0320829 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0319066 |
| MKI67 | marker of proliferation Ki-67 | -0.0318883 |
| RPLP0 | ribosomal protein, large, P0 | -0.0312788 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0312625 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0308027 |
| NHSL1 | NHS-like 1 | -0.0306941 |
| UBC | ubiquitin C | -0.0306442 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0306348 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0304952 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0304708 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302607 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0296717 |
| CLDN1 | claudin 1 | -0.0293852 |
| CDK6 | cyclin-dependent kinase 6 | -0.0292668 |
| RPS13 | ribosomal protein S13 | -0.0289616 |
| USP34 | ubiquitin specific peptidase 34 | -0.0287276 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0283197 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0282363 |
| WWOX | WW domain containing oxidoreductase | -0.0280257 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0277723 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0277281 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0277217 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0275397 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0275383 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0275325 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.027496 |
| DTNA | dystrobrevin, alpha | -0.0274654 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0273919 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0273055 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.027219 |
