| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.0548746 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0543384 |
| KYNU | kynureninase | 0.0520131 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0388348 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0383633 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0340801 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0335507 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.029397 |
| SMAD3 | SMAD family member 3 | 0.0292854 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0288886 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0279705 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0276435 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.026291 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0260943 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0251317 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0248179 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0244169 |
| KLF6 | Kruppel-like factor 6 | 0.0238881 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0222151 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0215098 |
| RASA2 | RAS p21 protein activator 2 | 0.0198467 |
| MYO1B | myosin IB | 0.0198338 |
| ANXA1 | annexin A1 | 0.0195224 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0193735 |
| SPAG9 | sperm associated antigen 9 | 0.0193555 |
| GPRIN3 | GPRIN family member 3 | 0.0184922 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0178542 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0174486 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0169669 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0164164 |
| APP | amyloid beta (A4) precursor protein | 0.0162993 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0152376 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0152335 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0151621 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0144276 |
| PLEC | plectin | 0.0142618 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0140051 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0139676 |
| EREG | epiregulin | 0.0137134 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0136592 |
| RHOB | ras homolog family member B | 0.0134177 |
| XDH | xanthine dehydrogenase | 0.0133805 |
| RPL4 | ribosomal protein L4 | 0.01328 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0127297 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.012509 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0124905 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0124598 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0123014 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0118331 |
| STC1 | stanniocalcin 1 | 0.0117743 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0116661 |
| PDZD8 | PDZ domain containing 8 | 0.0112583 |
| NGLY1 | N-glycanase 1 | 0.0112487 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0111361 |
| UBQLN1 | ubiquilin 1 | 0.0110648 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0110577 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0109822 |
| SQOR | sulfide quinone oxidoreductase | 0.0109582 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0106579 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0104107 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0103562 |
| RPSA | ribosomal protein SA | 0.010349 |
| FMNL2 | formin-like 2 | 0.0102823 |
| TMSB4X | thymosin beta 4, X-linked | 0.0102128 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0102127 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0101686 |
| IFNGR1 | interferon gamma receptor 1 | 0.0101001 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0100068 |
| RARB | retinoic acid receptor, beta | 0.00980051 |
| ETNK1 | ethanolamine kinase 1 | 0.00975942 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00955974 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00944491 |
| DENND5A | DENN/MADD domain containing 5A | 0.00935873 |
| ARRDC3 | arrestin domain containing 3 | 0.00929667 |
| H1-4 | H1.4 linker histone, cluster member | 0.00917048 |
| CYTH1 | cytohesin 1 | 0.00915345 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0091384 |
| RPS15A | ribosomal protein S15a | 0.00901428 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.00884128 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.00883714 |
| TDRD7 | tudor domain containing 7 | 0.00881636 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00874299 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0086648 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.00864931 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.00843703 |
| ANO6 | anoctamin 6 | 0.00836114 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.00835071 |
| TMOD1 | tropomodulin 1 | 0.00832113 |
| SOCS6 | suppressor of cytokine signaling 6 | 0.00831656 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.00828079 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00827259 |
| SERINC1 | serine incorporator 1 | 0.00826811 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.00819885 |
| RNF19B | ring finger protein 19B | 0.00807947 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00806595 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00804462 |
| RPL41 | ribosomal protein L41 | 0.00796745 |
| SMOX | spermine oxidase | 0.00796432 |
| CTSL | cathepsin L | 0.00789866 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.00789239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197613 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.161768 |
| VIM | vimentin | -0.154593 |
| TMSB10 | thymosin beta 10 | -0.139747 |
| NDRG1 | N-myc downstream regulated 1 | -0.128552 |
| ACTG1 | actin gamma 1 | -0.125312 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.114041 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0920356 |
| EFNA5 | ephrin-A5 | -0.0885795 |
| POTEF | POTE ankyrin domain family, member F | -0.0874536 |
| RPS6 | ribosomal protein S6 | -0.085075 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0839977 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0839718 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0817583 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0739805 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0701592 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0657234 |
| EGFR | epidermal growth factor receptor | -0.065551 |
| KRT81 | keratin 81, type II | -0.065015 |
| RPS19 | ribosomal protein S19 | -0.0617469 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0587655 |
| PFN1 | profilin 1 | -0.0559587 |
| CA12 | carbonic anhydrase XII | -0.055823 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0554691 |
| CCDC88A | coiled-coil domain containing 88A | -0.0551932 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0542162 |
| MYADM | myeloid-associated differentiation marker | -0.0538704 |
| ANXA2 | annexin A2 | -0.0535468 |
| AXL | AXL receptor tyrosine kinase | -0.0532428 |
| MT2A | metallothionein 2A | -0.052122 |
| S100A6 | S100 calcium binding protein A6 | -0.0512278 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0507523 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0483257 |
| FLNB | filamin B, beta | -0.0474705 |
| HMGA1 | high mobility group AT-hook 1 | -0.0468193 |
| EGR1 | early growth response 1 | -0.0467743 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0457996 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.045204 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0426483 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0426291 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0424839 |
| RPS16 | ribosomal protein S16 | -0.0419766 |
| GOLGA4 | golgin A4 | -0.0418968 |
| MCL1 | myeloid cell leukemia 1 | -0.0417777 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0417092 |
| RIN2 | Ras and Rab interactor 2 | -0.0405727 |
| EHBP1 | EH domain binding protein 1 | -0.0404792 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0403954 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0401333 |
| ANXA4 | annexin A4 | -0.0399688 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.039011 |
| PCBP2 | poly(rC) binding protein 2 | -0.038961 |
| FTL | ferritin, light polypeptide | -0.0387563 |
| PKM | pyruvate kinase, muscle | -0.0386688 |
| RPLP1 | ribosomal protein, large, P1 | -0.0376313 |
| MT1X | metallothionein 1X | -0.0365645 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0359649 |
| HIP1 | huntingtin interacting protein 1 | -0.0355464 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0351834 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0349909 |
| RND3 | Rho family GTPase 3 | -0.0343427 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0332648 |
| PRKCA | protein kinase C, alpha | -0.0330514 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0326083 |
| RPL28 | ribosomal protein L28 | -0.0325176 |
| S100A10 | S100 calcium binding protein A10 | -0.0321522 |
| RPS13 | ribosomal protein S13 | -0.032018 |
| SMYD3 | SET and MYND domain containing 3 | -0.0316326 |
| RPS23 | ribosomal protein S23 | -0.0314176 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0313913 |
| FBXO11 | F-box protein 11 | -0.0304246 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0299243 |
| GOLGB1 | golgin B1 | -0.0297408 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0289978 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0289851 |
| ASTN2 | astrotactin 2 | -0.0288022 |
| PTMA | prothymosin, alpha | -0.0286045 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0283787 |
| PDE10A | phosphodiesterase 10A | -0.0283635 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0279139 |
| BPTF | bromodomain PHD finger transcription factor | -0.02763 |
| RNF213 | ring finger protein 213 | -0.0274881 |
| RPL35A | ribosomal protein L35a | -0.0273842 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0273515 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0271495 |
| MYO10 | myosin X | -0.0271113 |
| TPM4 | tropomyosin 4 | -0.0268764 |
| RPL8 | ribosomal protein L8 | -0.0268708 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0267591 |
| TPM1 | tropomyosin 1 (alpha) | -0.0267395 |
| USP34 | ubiquitin specific peptidase 34 | -0.0266934 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0265205 |
| RPS11 | ribosomal protein S11 | -0.0261577 |
| JMJD1C | jumonji domain containing 1C | -0.0260922 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.025944 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0258812 |
| UBC | ubiquitin C | -0.0257999 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0257879 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0256438 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.025417 |
