| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.118686 |
| MEST | mesoderm specific transcript | 0.0759728 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0699605 |
| COL1A2 | collagen, type I, alpha 2 | 0.0562904 |
| PRELID2 | PRELI domain containing 2 | 0.0518708 |
| MAP1B | microtubule-associated protein 1B | 0.051817 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0456975 |
| RAD51B | RAD51 paralog B | 0.0441807 |
| EZR | ezrin | 0.0414862 |
| TMSB4X | thymosin beta 4, X-linked | 0.0400265 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0353989 |
| MEOX2 | mesenchyme homeobox 2 | 0.0332665 |
| RHOA | ras homolog family member A | 0.031522 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0314535 |
| PDE10A | phosphodiesterase 10A | 0.0285446 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0278026 |
| HOXA3 | homeobox A3 | 0.0262483 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0259213 |
| SPAG9 | sperm associated antigen 9 | 0.0256261 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0252874 |
| DIAPH3 | diaphanous-related formin 3 | 0.0246273 |
| HOXC6 | homeobox C6 | 0.0239508 |
| DUSP16 | dual specificity phosphatase 16 | 0.022394 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.021418 |
| VEGFA | vascular endothelial growth factor A | 0.0214081 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0196339 |
| USP3 | ubiquitin specific peptidase 3 | 0.0193609 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0193039 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0184531 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0184423 |
| ATG10 | autophagy related 10 | 0.0181006 |
| RPL3 | ribosomal protein L3 | 0.0177838 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0168636 |
| RHOB | ras homolog family member B | 0.0162516 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0161927 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0158407 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0158246 |
| ARRDC3 | arrestin domain containing 3 | 0.01574 |
| SHTN1 | shootin 1 | 0.0157144 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0157021 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.0156507 |
| ECT2 | epithelial cell transforming 2 | 0.0156339 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0156309 |
| BOC | BOC cell adhesion associated, oncogene regulated | 0.0156159 |
| AOPEP | aminopeptidase O (putative) | 0.015594 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0152809 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0151919 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0148183 |
| INVS | inversin | 0.0147584 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0146991 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0146201 |
| CDK19 | cyclin-dependent kinase 19 | 0.014556 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0145163 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0144977 |
| EXOC6B | exocyst complex component 6B | 0.0144092 |
| PCDH7 | protocadherin 7 | 0.0143396 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0142069 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0141855 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0141808 |
| QKI | QKI, KH domain containing, RNA binding | 0.0139802 |
| LMNB1 | lamin B1 | 0.0138586 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0138507 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0138477 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0136316 |
| DBN1 | drebrin 1 | 0.0135939 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0135518 |
| TBCD | tubulin folding cofactor D | 0.0134823 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.0130679 |
| COL5A2 | collagen, type V, alpha 2 | 0.0128986 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0128647 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0128375 |
| DMXL1 | Dmx-like 1 | 0.0128232 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0127899 |
| FAM219A | family with sequence similarity 219, member A | 0.0127774 |
| CENPF | centromere protein F, 350/400kDa | 0.0127391 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0127164 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.012564 |
| CCNG2 | cyclin G2 | 0.0123317 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0123148 |
| RARB | retinoic acid receptor, beta | 0.0122986 |
| HYOU1 | hypoxia up-regulated 1 | 0.0122842 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0121229 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.012059 |
| CBX5 | chromobox homolog 5 | 0.011921 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0119099 |
| PRRC2A | proline-rich coiled-coil 2A | 0.011873 |
| HOXC4 | homeobox C4 | 0.0118168 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.0117423 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0117287 |
| DCTN2 | dynactin 2 (p50) | 0.0117114 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 0.0115733 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.0115631 |
| LIF | leukemia inhibitory factor | 0.0115473 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.0115368 |
| TSC22D3 | TSC22 domain family, member 3 | 0.0115218 |
| CCDC82 | coiled-coil domain containing 82 | 0.0114388 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0113831 |
| RPSA | ribosomal protein SA | 0.0113773 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.011355 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.0112673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.173722 |
| CADM2 | cell adhesion molecule 2 | -0.10149 |
| MGP | matrix Gla protein | -0.0958144 |
| PTMA | prothymosin, alpha | -0.0873547 |
| RPS8 | ribosomal protein S8 | -0.0632228 |
| GOLGA4 | golgin A4 | -0.0629286 |
| ACTG1 | actin gamma 1 | -0.0622604 |
| MT2A | metallothionein 2A | -0.0586355 |
| RPLP1 | ribosomal protein, large, P1 | -0.056826 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0549371 |
| RPS6 | ribosomal protein S6 | -0.052708 |
| RPS24 | ribosomal protein S24 | -0.0523594 |
| HMGA2 | high mobility group AT-hook 2 | -0.051289 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0500032 |
| TMSB10 | thymosin beta 10 | -0.0496825 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0496794 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0468844 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0467469 |
| RPL35A | ribosomal protein L35a | -0.0466569 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0466378 |
| RPL37A | ribosomal protein L37a | -0.0461384 |
| ERBIN | erbb2 interacting protein | -0.0461378 |
| NFIA | nuclear factor I/A | -0.0459754 |
| RPL34 | ribosomal protein L34 | -0.0451106 |
| IER3 | immediate early response 3 | -0.044561 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0445473 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0444549 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0436516 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0427233 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0423731 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0420778 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0414583 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0401013 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0389049 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0387382 |
| VCL | vinculin | -0.0386649 |
| RACK1 | receptor for activated C kinase 1 | -0.0381473 |
| RPL12 | ribosomal protein L12 | -0.0378759 |
| KAZN | kazrin, periplakin interacting protein | -0.0374681 |
| RPL23 | ribosomal protein L23 | -0.0373653 |
| SMYD3 | SET and MYND domain containing 3 | -0.0370216 |
| RPLP2 | ribosomal protein, large, P2 | -0.0368497 |
| RPS12 | ribosomal protein S12 | -0.0367403 |
| RPL26 | ribosomal protein L26 | -0.0349861 |
| RPL31 | ribosomal protein L31 | -0.0346072 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0345763 |
| FTL | ferritin, light polypeptide | -0.0337284 |
| LDHA | lactate dehydrogenase A | -0.0327446 |
| RPS25 | ribosomal protein S25 | -0.032401 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0323887 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0315289 |
| RPS14 | ribosomal protein S14 | -0.0314814 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.030895 |
| RPS27A | ribosomal protein S27a | -0.0307441 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0305756 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0304423 |
| RPS13 | ribosomal protein S13 | -0.0303754 |
| CTBP2 | C-terminal binding protein 2 | -0.0301104 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0299136 |
| TPM4 | tropomyosin 4 | -0.0294726 |
| RPS3 | ribosomal protein S3 | -0.0294277 |
| MTDH | metadherin | -0.029135 |
| RPL11 | ribosomal protein L11 | -0.0291159 |
| RBM25 | RNA binding motif protein 25 | -0.0289366 |
| RPL19 | ribosomal protein L19 | -0.0287686 |
| NDRG1 | N-myc downstream regulated 1 | -0.0282896 |
| CANX | calnexin | -0.028282 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0282359 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0282097 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0279553 |
| RPLP0 | ribosomal protein, large, P0 | -0.0275416 |
| RPS19 | ribosomal protein S19 | -0.0274476 |
| RPS23 | ribosomal protein S23 | -0.0269369 |
| PHF3 | PHD finger protein 3 | -0.0268338 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0265432 |
| SIK3 | SIK family kinase 3 | -0.0265133 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0264709 |
| RPL37 | ribosomal protein L37 | -0.0264251 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0260393 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0257684 |
| RPL13A | ribosomal protein L13a | -0.0256541 |
| GPHN | gephyrin | -0.0253971 |
| RPS10 | ribosomal protein S10 | -0.0253834 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0252573 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0248492 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0247004 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0244465 |
| RLF | rearranged L-myc fusion | -0.0244062 |
| PEG10 | paternally expressed 10 | -0.0243609 |
| CDK13 | cyclin-dependent kinase 13 | -0.0241586 |
| TULP4 | tubby like protein 4 | -0.0238395 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0237042 |
| RPL9 | ribosomal protein L9 | -0.0236256 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0235853 |
| FBXO11 | F-box protein 11 | -0.0235532 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0230483 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0230219 |
| PGK1 | phosphoglycerate kinase 1 | -0.0229727 |
| RPL36 | ribosomal protein L36 | -0.0228511 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0228128 |
