| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMTK2 | lemur tyrosine kinase 2 | 0.0852029 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0617073 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0537125 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0498772 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0458283 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0412775 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.040254 |
| SPAG9 | sperm associated antigen 9 | 0.0399617 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0393046 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0391016 |
| PTMA | prothymosin, alpha | 0.038206 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0362027 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0358496 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0349356 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.034364 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0336654 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0329013 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0315033 |
| DST | dystonin | 0.031014 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0303328 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0300937 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.029562 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0294553 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0293354 |
| RNF145 | ring finger protein 145 | 0.0291814 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0290134 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0285999 |
| NUP58 | nucleoporin 58 | 0.0284153 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0281788 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0279881 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0279802 |
| NCKAP1 | NCK-associated protein 1 | 0.0275892 |
| AFDN | afadin, adherens junction formation factor | 0.0270245 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0268171 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0261548 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0256434 |
| MYO6 | myosin VI | 0.0256252 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0249655 |
| ACVR1 | activin A receptor, type I | 0.0249384 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.024845 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0247647 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0242864 |
| PLEC | plectin | 0.0242799 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0240422 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0236993 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0233698 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0233615 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0232682 |
| STK39 | serine threonine kinase 39 | 0.0226601 |
| RHEB | Ras homolog enriched in brain | 0.0225644 |
| RREB1 | ras responsive element binding protein 1 | 0.02234 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0221506 |
| TOP1 | topoisomerase (DNA) I | 0.0221078 |
| USP3 | ubiquitin specific peptidase 3 | 0.0220447 |
| ZNF292 | zinc finger protein 292 | 0.021778 |
| MXD1 | MAX dimerization protein 1 | 0.0215637 |
| XPO1 | exportin 1 | 0.0213263 |
| CCNL1 | cyclin L1 | 0.0212244 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0211712 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0206961 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0206283 |
| RCOR1 | REST corepressor 1 | 0.0204189 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0202372 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0201209 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0200918 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0199914 |
| FAM13A | family with sequence similarity 13, member A | 0.0196526 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0185314 |
| PUM2 | pumilio RNA-binding family member 2 | 0.018258 |
| AHR | aryl hydrocarbon receptor | 0.0182119 |
| ABI1 | abl-interactor 1 | 0.0181606 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0181094 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0178672 |
| CD164 | CD164 molecule, sialomucin | 0.0178609 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0177042 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0176666 |
| LYZ | lysozyme | 0.0175387 |
| PTK2 | protein tyrosine kinase 2 | 0.0175098 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0174447 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0174033 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0173221 |
| MATR3 | matrin 3 | 0.0172151 |
| SLMAP | sarcolemma associated protein | 0.0171371 |
| STRN | striatin, calmodulin binding protein | 0.016812 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.016721 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0166462 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0165772 |
| TMEM41B | transmembrane protein 41B | 0.016361 |
| ATP11B | ATPase, class VI, type 11B | 0.0161155 |
| NPTN | neuroplastin | 0.0160397 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.0159552 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0159097 |
| FAR1 | fatty acyl CoA reductase 1 | 0.015881 |
| SLK | STE20-like kinase | 0.0158363 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0158187 |
| QKI | QKI, KH domain containing, RNA binding | 0.0157601 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0157592 |
| USP12 | ubiquitin specific peptidase 12 | 0.0157293 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0157199 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0156987 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.169733 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.164439 |
| TMSB10 | thymosin beta 10 | -0.150975 |
| FLNB | filamin B, beta | -0.150656 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.143177 |
| EFNA5 | ephrin-A5 | -0.135064 |
| NDRG1 | N-myc downstream regulated 1 | -0.124625 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.121813 |
| DOCK5 | dedicator of cytokinesis 5 | -0.117558 |
| EGFR | epidermal growth factor receptor | -0.10699 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.106627 |
| S100A10 | S100 calcium binding protein A10 | -0.0950743 |
| VIM | vimentin | -0.092052 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0844796 |
| LAMB3 | laminin, beta 3 | -0.0842581 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0837674 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0807407 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0782883 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.075422 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0727198 |
| ASPH | aspartate beta-hydroxylase | -0.0689656 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.064202 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0632209 |
| TRRAP | transformation/transcription domain-associated protein | -0.0631677 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0626322 |
| DIAPH2 | diaphanous-related formin 2 | -0.0597317 |
| HMGA2 | high mobility group AT-hook 2 | -0.0588853 |
| RASAL2 | RAS protein activator like 2 | -0.0588465 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0580172 |
| POTEF | POTE ankyrin domain family, member F | -0.0580091 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0574986 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0567444 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0566 |
| ANXA2 | annexin A2 | -0.0562848 |
| SP100 | SP100 nuclear antigen | -0.054331 |
| EGR1 | early growth response 1 | -0.0538076 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0534664 |
| LAMA4 | laminin, alpha 4 | -0.0518068 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0511383 |
| TXNIP | thioredoxin interacting protein | -0.0510541 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0504495 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0502087 |
| LAMC2 | laminin, gamma 2 | -0.0501268 |
| AHNAK | AHNAK nucleoprotein | -0.0495997 |
| HMGA1 | high mobility group AT-hook 1 | -0.0476983 |
| VCL | vinculin | -0.0467356 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0466343 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0457865 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.045662 |
| MCL1 | myeloid cell leukemia 1 | -0.0455739 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0454492 |
| CLMP | CXADR-like membrane protein | -0.0449569 |
| DSG2 | desmoglein 2 | -0.0447519 |
| FBXO11 | F-box protein 11 | -0.0433731 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0430414 |
| FERMT1 | fermitin family member 1 | -0.0415742 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0410651 |
| NPSR1 | neuropeptide S receptor 1 | -0.0404378 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0404364 |
| VCAN | versican | -0.0393191 |
| EHBP1 | EH domain binding protein 1 | -0.0391016 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0390415 |
| RPS21 | ribosomal protein S21 | -0.0387369 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0385871 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0384684 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0381964 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.037983 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.037489 |
| SDC4 | syndecan 4 | -0.037399 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0370812 |
| PRELID2 | PRELI domain containing 2 | -0.0370778 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0370509 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0366623 |
| PRSS3 | protease, serine, 3 | -0.0366622 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0365163 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0364561 |
| RPS13 | ribosomal protein S13 | -0.0362141 |
| MYOF | myoferlin | -0.0361071 |
| OSMR | oncostatin M receptor | -0.0360848 |
| RPL35A | ribosomal protein L35a | -0.0358696 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0353686 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0352134 |
| PMM2 | phosphomannomutase 2 | -0.0351852 |
| RPL12 | ribosomal protein L12 | -0.0351386 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0350598 |
| BCL2L1 | BCL2-like 1 | -0.0346712 |
| UBC | ubiquitin C | -0.0343503 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0343478 |
| RPLP2 | ribosomal protein, large, P2 | -0.0342906 |
| CALU | calumenin | -0.0335345 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0334484 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0333927 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0332859 |
| TGM2 | transglutaminase 2 | -0.0331169 |
| RPL8 | ribosomal protein L8 | -0.0327056 |
| RPLP1 | ribosomal protein, large, P1 | -0.0325596 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0322308 |
| KLK10 | kallikrein-related peptidase 10 | -0.0321246 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0321011 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0320506 |
