| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.1419 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0962722 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0951761 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0746099 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0717164 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0714792 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0483241 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0475882 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.0453507 |
| CEP250 | centrosomal protein 250kDa | 0.0417726 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0413159 |
| FADS2 | fatty acid desaturase 2 | 0.0405295 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0387386 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0385804 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0385147 |
| ECT2 | epithelial cell transforming 2 | 0.0339502 |
| AHNAK | AHNAK nucleoprotein | 0.0329347 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0316345 |
| KAZN | kazrin, periplakin interacting protein | 0.0313069 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0305753 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0290711 |
| CLIC4 | chloride intracellular channel 4 | 0.0289018 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0286002 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.0285477 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0276552 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0274184 |
| ENAH | enabled homolog (Drosophila) | 0.0270624 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0270361 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0265243 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0263833 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0251345 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0241329 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.023993 |
| MAP7 | microtubule-associated protein 7 | 0.0239462 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0238008 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0236354 |
| NREP | neuronal regeneration related protein | 0.0236335 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0236309 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0235246 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.023308 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0229082 |
| PRLR | prolactin receptor | 0.0228636 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0225293 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0219167 |
| S100P | S100 calcium binding protein P | 0.0215765 |
| NEBL | nebulette | 0.021385 |
| EFNA1 | ephrin-A1 | 0.0212317 |
| MYO9A | myosin IXA | 0.0209644 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0209144 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0203454 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0200827 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0200296 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0199362 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0196305 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0194817 |
| CENPF | centromere protein F, 350/400kDa | 0.0194446 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0194328 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0193551 |
| FRY | furry homolog (Drosophila) | 0.0192399 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0191157 |
| DUSP16 | dual specificity phosphatase 16 | 0.0189128 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0187693 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0186608 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0186538 |
| MTMR12 | myotubularin related protein 12 | 0.018592 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.0185694 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0183954 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0183794 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0183331 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0179784 |
| MVD | mevalonate (diphospho) decarboxylase | 0.0177947 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0177909 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0177168 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0174154 |
| MBOAT1 | membrane bound O-acyltransferase domain containing 1 | 0.0171539 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.017146 |
| PDE10A | phosphodiesterase 10A | 0.0171062 |
| MSMO1 | methylsterol monooxygenase 1 | 0.017025 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0170038 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0168855 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0167988 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0166328 |
| TENM2 | teneurin transmembrane protein 2 | 0.0165685 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0163821 |
| FDPS | farnesyl diphosphate synthase | 0.0163649 |
| KIF16B | kinesin family member 16B | 0.0163147 |
| GMPS | guanine monphosphate synthase | 0.0162811 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0162303 |
| TC2N | tandem C2 domains, nuclear | 0.0162176 |
| TPR | translocated promoter region, nuclear basket protein | 0.0161991 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0161968 |
| RNF114 | ring finger protein 114 | 0.0160655 |
| CTBP2 | C-terminal binding protein 2 | 0.0159877 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0158112 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.0156765 |
| XBP1 | X-box binding protein 1 | 0.0156682 |
| MAPK4 | mitogen-activated protein kinase 4 | 0.0156299 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0155807 |
| RPS3 | ribosomal protein S3 | 0.0155339 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0154815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NCOA3 | nuclear receptor coactivator 3 | -0.118851 |
| VMP1 | vacuole membrane protein 1 | -0.0957039 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0926533 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0904863 |
| NDRG1 | N-myc downstream regulated 1 | -0.0813512 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0810579 |
| USP53 | ubiquitin specific peptidase 53 | -0.077831 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0733884 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0725737 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0681664 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0670056 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0664279 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.065266 |
| ACTG1 | actin gamma 1 | -0.0642178 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0625555 |
| SMYD3 | SET and MYND domain containing 3 | -0.0611915 |
| MT2A | metallothionein 2A | -0.0560573 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0549422 |
| RPL19 | ribosomal protein L19 | -0.0547166 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0543416 |
| ASPH | aspartate beta-hydroxylase | -0.052407 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0521829 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0521697 |
| CLTC | clathrin, heavy chain (Hc) | -0.0519746 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0518639 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0502304 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0499993 |
| MCL1 | myeloid cell leukemia 1 | -0.0488561 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0484543 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0480221 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0468799 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0446005 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0441661 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0439863 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0423911 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0417485 |
| EGFR | epidermal growth factor receptor | -0.0415045 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0409317 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0405801 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0381063 |
| DTNA | dystrobrevin, alpha | -0.0377131 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0356871 |
| POTEF | POTE ankyrin domain family, member F | -0.0356649 |
| ZNF148 | zinc finger protein 148 | -0.0355263 |
| AHR | aryl hydrocarbon receptor | -0.0352273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0349784 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0349239 |
| B2M | beta-2-microglobulin | -0.0347557 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0345018 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0344856 |
| LMNA | lamin A/C | -0.0341687 |
| MYOF | myoferlin | -0.0334302 |
| SMAD3 | SMAD family member 3 | -0.0333237 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0325815 |
| NTN4 | netrin 4 | -0.0317056 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0316978 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0314666 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0311173 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0310362 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0306731 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0305129 |
| AREG | amphiregulin | -0.030274 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0301278 |
| SET | SET nuclear proto-oncogene | -0.0294784 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0293508 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0293234 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0292377 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0288897 |
| LDHA | lactate dehydrogenase A | -0.0285402 |
| CCND1 | cyclin D1 | -0.0285207 |
| RAB22A | RAB22A, member RAS oncogene family | -0.02842 |
| TXNRD1 | thioredoxin reductase 1 | -0.0280807 |
| TMEM45B | transmembrane protein 45B | -0.0280394 |
| SYTL2 | synaptotagmin-like 2 | -0.0277082 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0276262 |
| MYO9B | myosin IXB | -0.0276118 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275781 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0273261 |
| RIOK3 | RIO kinase 3 | -0.0272781 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0267402 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) | -0.0263234 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0263063 |
| SPAG9 | sperm associated antigen 9 | -0.0260888 |
| FNBP1 | formin binding protein 1 | -0.0260285 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0258399 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0257913 |
| ANXA2 | annexin A2 | -0.0257418 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0257187 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0255565 |
| CD44 | CD44 molecule (Indian blood group) | -0.0254196 |
| CCNI | cyclin I | -0.0252104 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0249165 |
| OSMR | oncostatin M receptor | -0.02483 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0247833 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0247212 |
| UBC | ubiquitin C | -0.0247098 |
| RPS6 | ribosomal protein S6 | -0.0246432 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0243339 |
| SEPTIN9 | septin 9 | -0.0241221 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0240343 |
