| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Pitavastatin (Calcium)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.130436 |
| JMJD1C | jumonji domain containing 1C | 0.110061 |
| RTN4 | reticulon 4 | 0.0856112 |
| MEF2A | myocyte enhancer factor 2A | 0.0759894 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.06829 |
| MAP1B | microtubule-associated protein 1B | 0.0671635 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0671548 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0651648 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0593224 |
| NUP58 | nucleoporin 58 | 0.0573635 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0522845 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0507124 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0488042 |
| RPS6 | ribosomal protein S6 | 0.0464421 |
| VMP1 | vacuole membrane protein 1 | 0.0457839 |
| SRPK2 | SRSF protein kinase 2 | 0.0453318 |
| TXNRD1 | thioredoxin reductase 1 | 0.0451173 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0409715 |
| APP | amyloid beta (A4) precursor protein | 0.0403994 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0403663 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.039402 |
| NPAS3 | neuronal PAS domain protein 3 | 0.039303 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.038023 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0373646 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0371541 |
| OGA | O-GlcNAcase | 0.0363576 |
| QKI | QKI, KH domain containing, RNA binding | 0.0362612 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0362592 |
| PGK1 | phosphoglycerate kinase 1 | 0.0362435 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0360492 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0357434 |
| MACO1 | macoilin 1 | 0.0355496 |
| PTK2 | protein tyrosine kinase 2 | 0.0354083 |
| CASC3 | cancer susceptibility candidate 3 | 0.0353808 |
| PTMA | prothymosin, alpha | 0.0353125 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.035107 |
| IPO7 | importin 7 | 0.034948 |
| USP24 | ubiquitin specific peptidase 24 | 0.0348762 |
| ZNF292 | zinc finger protein 292 | 0.0348464 |
| FAM162A | family with sequence similarity 162, member A | 0.0344276 |
| FNBP1L | formin binding protein 1-like | 0.0342398 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0340722 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0336871 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330909 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0328948 |
| TENM3 | teneurin transmembrane protein 3 | 0.0328865 |
| PRRC2C | proline-rich coiled-coil 2C | 0.032654 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0325518 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0324488 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0323889 |
| ANXA2 | annexin A2 | 0.0320997 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0319801 |
| XPO1 | exportin 1 | 0.0317306 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 0.0310971 |
| LRRC1 | leucine rich repeat containing 1 | 0.0310166 |
| PCNX1 | pecanex 1 | 0.0310022 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0308577 |
| MRTFA | myocardin related transcription factor A | 0.030774 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0304567 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0304117 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0302327 |
| SETD5 | SET domain containing 5 | 0.0302117 |
| USP3 | ubiquitin specific peptidase 3 | 0.0301189 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0300781 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0299923 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0295674 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.0291972 |
| EZR | ezrin | 0.0289843 |
| OLA1 | Obg-like ATPase 1 | 0.0288848 |
| KIF13A | kinesin family member 13A | 0.0288501 |
| NBAS | neuroblastoma amplified sequence | 0.0286956 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0284719 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0283831 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0282225 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0281701 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0280307 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0279645 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0278526 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0277593 |
| CARD18 | caspase recruitment domain family, member 18 | 0.027633 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0273 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0271484 |
| RHEB | Ras homolog enriched in brain | 0.027139 |
| MYL12B | myosin, light chain 12B, regulatory | 0.027028 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0270061 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0269447 |
| SPAG9 | sperm associated antigen 9 | 0.0265365 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0265007 |
| CRY1 | cryptochrome circadian clock 1 | 0.0262115 |
| CDC73 | cell division cycle 73 | 0.0260633 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0260072 |
| WASF2 | WAS protein family, member 2 | 0.025855 |
| RPL3 | ribosomal protein L3 | 0.0258454 |
| MEMO1 | mediator of cell motility 1 | 0.025765 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.025733 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0256257 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.025606 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0255577 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0254627 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0254409 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | -0.212682 |
| NEBL | nebulette | -0.196587 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.157789 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.147874 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.110058 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0884802 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0713068 |
| VCL | vinculin | -0.0671215 |
| CADM2 | cell adhesion molecule 2 | -0.0653462 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0638406 |
| RAD51B | RAD51 paralog B | -0.0602921 |
| NFIA | nuclear factor I/A | -0.0508019 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0493587 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0486024 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0478295 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0465054 |
| ATP9A | ATPase, class II, type 9A | -0.0462396 |
| SMYD3 | SET and MYND domain containing 3 | -0.04527 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0432216 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0426072 |
| DENND1A | DENN/MADD domain containing 1A | -0.0407838 |
| ACTG1 | actin gamma 1 | -0.0406721 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0376346 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0368502 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0368362 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0358549 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0353609 |
| RCC1 | regulator of chromosome condensation 1 | -0.0349125 |
| KIAA1958 | KIAA1958 | -0.0337822 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0327372 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0325989 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0310961 |
| ZFHX4 | zinc finger homeobox 4 | -0.0306023 |
| ATP11A | ATPase, class VI, type 11A | -0.029596 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0293094 |
| WLS | wntless Wnt ligand secretion mediator | -0.0292527 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | -0.0292224 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | -0.0291157 |
| CCDC138 | coiled-coil domain containing 138 | -0.0278563 |
| PYGL | phosphorylase, glycogen, liver | -0.0277586 |
| MSH4 | mutS homolog 4 | -0.0270245 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0268417 |
| AEBP2 | AE binding protein 2 | -0.0264998 |
| CDK13 | cyclin-dependent kinase 13 | -0.0264636 |
| NUP98 | nucleoporin 98kDa | -0.0263074 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0259962 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0251915 |
| METTL2B | methyltransferase like 2B | -0.02492 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -0.0247291 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0246668 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0242826 |
| PCNX4 | pecanex 4 | -0.023784 |
| HDAC4 | histone deacetylase 4 | -0.0236613 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0235216 |
| ALMS1 | Alstrom syndrome protein 1 | -0.0233926 |
| GSE1 | Gse1 coiled-coil protein | -0.022656 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0224046 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0222223 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.021775 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0217124 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0213454 |
| INTS6 | integrator complex subunit 6 | -0.0211488 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0210678 |
| PHF3 | PHD finger protein 3 | -0.0210155 |
| RPAP2 | RNA polymerase II associated protein 2 | -0.0208306 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0207491 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -0.0206531 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0205481 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0203664 |
| CDH18 | cadherin 18, type 2 | -0.0203388 |
| TMEM14B | transmembrane protein 14B | -0.020196 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0201811 |
| RPL38 | ribosomal protein L38 | -0.0201717 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.0201258 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -0.0201117 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.02008 |
| SHROOM3 | shroom family member 3 | -0.0200304 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0199541 |
| SIK3 | SIK family kinase 3 | -0.0198709 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0198196 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0197907 |
| E2F3 | E2F transcription factor 3 | -0.0197493 |
| GLG1 | golgi glycoprotein 1 | -0.0195951 |
| GIGYF2 | GRB10 interacting GYF protein 2 | -0.0195174 |
| EHBP1 | EH domain binding protein 1 | -0.0194474 |
| BPTF | bromodomain PHD finger transcription factor | -0.019189 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0191786 |
| APTX | aprataxin | -0.0191445 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0190736 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0190616 |
| NXN | nucleoredoxin | -0.0189161 |
| MYO1E | myosin IE | -0.0189025 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | -0.0188983 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0187534 |
| UBE3D | ubiquitin protein ligase E3D | -0.0187022 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0186732 |
| CUX1 | cut-like homeobox 1 | -0.0186319 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0185275 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | -0.0183438 |
| GON4L | gon-4-like (C. elegans) | -0.0183374 |
