| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.133142 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0775328 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.066409 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0605176 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0589365 |
| FMN1 | formin 1 | 0.0546544 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0538151 |
| INSIG1 | insulin induced gene 1 | 0.053072 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0529223 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0457628 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0449963 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0423286 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0417249 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0406143 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0403848 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0390694 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0379882 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0379058 |
| CD44 | CD44 molecule (Indian blood group) | 0.0364718 |
| PI15 | peptidase inhibitor 15 | 0.0353748 |
| TNNC1 | troponin C type 1 (slow) | 0.0349036 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0345632 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0333482 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0327298 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0322022 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0319963 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0315318 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0315175 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0313856 |
| DST | dystonin | 0.0304499 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0303659 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0299593 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.029613 |
| RHOB | ras homolog family member B | 0.0291017 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0283376 |
| PLEC | plectin | 0.026984 |
| SRPK2 | SRSF protein kinase 2 | 0.0266871 |
| TAGLN2 | transgelin 2 | 0.0261849 |
| MSN | moesin | 0.0261298 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0257148 |
| CDC73 | cell division cycle 73 | 0.0245221 |
| RCAN1 | regulator of calcineurin 1 | 0.024408 |
| RTN4 | reticulon 4 | 0.0237481 |
| ATP9B | ATPase, class II, type 9B | 0.0236442 |
| ACTN4 | actinin, alpha 4 | 0.0233611 |
| AFDN | afadin, adherens junction formation factor | 0.0228483 |
| MRTFA | myocardin related transcription factor A | 0.0227496 |
| EZR | ezrin | 0.021882 |
| ITGB8 | integrin, beta 8 | 0.021319 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0211523 |
| UTRN | utrophin | 0.0209971 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0206087 |
| RHOA | ras homolog family member A | 0.0203097 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0197257 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0193795 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0192156 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.0188599 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0187616 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0187064 |
| ANXA2 | annexin A2 | 0.018571 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.0182645 |
| ANXA5 | annexin A5 | 0.0178038 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0174385 |
| SPAG9 | sperm associated antigen 9 | 0.017435 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0172093 |
| FBXO7 | F-box protein 7 | 0.017189 |
| MKRN1 | makorin ring finger protein 1 | 0.0171838 |
| CLIC4 | chloride intracellular channel 4 | 0.0170658 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0169233 |
| ADAMTS4 | ADAM metallopeptidase with thrombospondin type 1 motif, 4 | 0.0167048 |
| SHC4 | SHC (Src homology 2 domain containing) family, member 4 | 0.0166485 |
| MED13L | mediator complex subunit 13-like | 0.016511 |
| MT1X | metallothionein 1X | 0.016498 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0164378 |
| CD109 | CD109 molecule | 0.0163943 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0163603 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0163285 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0160139 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0159418 |
| AHNAK | AHNAK nucleoprotein | 0.0156656 |
| PYGB | phosphorylase, glycogen; brain | 0.015394 |
| AHR | aryl hydrocarbon receptor | 0.0152887 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 | 0.0150922 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0149279 |
| RNF145 | ring finger protein 145 | 0.0148822 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0147648 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0146253 |
| MYO10 | myosin X | 0.0145358 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0144755 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0144254 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0143934 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0141006 |
| NAV1 | neuron navigator 1 | 0.0140466 |
| SNX9 | sorting nexin 9 | 0.0138863 |
| APP | amyloid beta (A4) precursor protein | 0.0138516 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0137878 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0137088 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 0.0136174 |
| RPL3 | ribosomal protein L3 | 0.0132274 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0131709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.158416 |
| GPC6 | glypican 6 | -0.152952 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150387 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.146015 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.142321 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.133505 |
| ASPH | aspartate beta-hydroxylase | -0.113732 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.101278 |
| NLGN1 | neuroligin 1 | -0.0901041 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0724975 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0672825 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0641873 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0641727 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0619136 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0554609 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0549344 |
| PRELID2 | PRELI domain containing 2 | -0.0542167 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0538612 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0531238 |
| HLA-B | major histocompatibility complex, class I, B | -0.0515504 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0510103 |
| PHF21A | PHD finger protein 21A | -0.0506533 |
| VIM | vimentin | -0.050167 |
| PCDH7 | protocadherin 7 | -0.0501237 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0499955 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0489672 |
| CTTNBP2 | cortactin binding protein 2 | -0.0468831 |
| CALR | calreticulin | -0.0456435 |
| PTMA | prothymosin, alpha | -0.0450531 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.044522 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0442582 |
| GDF15 | growth differentiation factor 15 | -0.0433719 |
| PTCHD4 | patched domain containing 4 | -0.043297 |
| PTK2 | protein tyrosine kinase 2 | -0.0431805 |
| PARVB | parvin, beta | -0.0422489 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0411147 |
| CABIN1 | calcineurin binding protein 1 | -0.0399465 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0395517 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0393019 |
| CANX | calnexin | -0.0385239 |
| EGR1 | early growth response 1 | -0.0381556 |
| OXR1 | oxidation resistance 1 | -0.0372203 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0363199 |
| SCFD2 | sec1 family domain containing 2 | -0.036306 |
| NBAS | neuroblastoma amplified sequence | -0.0361975 |
| IFRD1 | interferon-related developmental regulator 1 | -0.036108 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0355563 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0354581 |
| ZNF704 | zinc finger protein 704 | -0.0345692 |
| CUX1 | cut-like homeobox 1 | -0.0334271 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.033081 |
| CADM1 | cell adhesion molecule 1 | -0.0329831 |
| TRIM2 | tripartite motif containing 2 | -0.032975 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0326333 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0323894 |
| LRRC23 | leucine rich repeat containing 23 | -0.0311474 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0309562 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0309154 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0306658 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306475 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0306322 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0305831 |
| GOLGA4 | golgin A4 | -0.0303751 |
| GPHN | gephyrin | -0.0302935 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0301994 |
| CDK14 | cyclin-dependent kinase 14 | -0.0301989 |
| RPLP1 | ribosomal protein, large, P1 | -0.030153 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0301019 |
| TLE4 | transducin-like enhancer of split 4 | -0.0298077 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0296262 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0294081 |
| MYO1E | myosin IE | -0.0291877 |
| FLNB | filamin B, beta | -0.0291589 |
| RPS8 | ribosomal protein S8 | -0.0284202 |
| IER3 | immediate early response 3 | -0.0277241 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0277082 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0274312 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0274078 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0272682 |
| CALU | calumenin | -0.0270809 |
| RPL35A | ribosomal protein L35a | -0.0270595 |
| RPL37A | ribosomal protein L37a | -0.0267579 |
| INTS6 | integrator complex subunit 6 | -0.0267487 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0265887 |
| RUNX1 | runt-related transcription factor 1 | -0.0264407 |
| TMEM178B | transmembrane protein 178B | -0.0263383 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0260398 |
| FUS | FUS RNA binding protein | -0.0258423 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0258379 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0257736 |
| GHR | growth hormone receptor | -0.025716 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0256807 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0256749 |
| GLG1 | golgi glycoprotein 1 | -0.0253333 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0252723 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0251887 |
| KDM2B | lysine (K)-specific demethylase 2B | -0.0250283 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0247253 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0245745 |
| NPR2 | natriuretic peptide receptor 2 | -0.0245689 |
