| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.13213 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.120283 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.113712 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.111355 |
| TSC22D2 | TSC22 domain family, member 2 | 0.110686 |
| FNDC3B | fibronectin type III domain containing 3B | 0.109042 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.100478 |
| TMSB10 | thymosin beta 10 | 0.0963119 |
| PTMA | prothymosin, alpha | 0.0952649 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0832095 |
| FAM13A | family with sequence similarity 13, member A | 0.0745661 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0738796 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.070662 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0703864 |
| TMSB4X | thymosin beta 4, X-linked | 0.0701455 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0675626 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.064897 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0646498 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0644116 |
| SPAG9 | sperm associated antigen 9 | 0.0613661 |
| CCNY | cyclin Y | 0.058242 |
| TXNRD1 | thioredoxin reductase 1 | 0.0569686 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0560831 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0554232 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0543848 |
| ENO1 | enolase 1, (alpha) | 0.0522461 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0521479 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0521215 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.051596 |
| NUP58 | nucleoporin 58 | 0.0514564 |
| RPL23 | ribosomal protein L23 | 0.050204 |
| USP3 | ubiquitin specific peptidase 3 | 0.0501538 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0494496 |
| TOP1 | topoisomerase (DNA) I | 0.04866 |
| APP | amyloid beta (A4) precursor protein | 0.0484849 |
| EZR | ezrin | 0.0483788 |
| TFG | TRK-fused gene | 0.0483557 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0473592 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0469101 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0463464 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0450021 |
| CCNL1 | cyclin L1 | 0.044954 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0445394 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0429401 |
| ANXA1 | annexin A1 | 0.0423156 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0421496 |
| GRB10 | growth factor receptor-bound protein 10 | 0.042085 |
| RTN4 | reticulon 4 | 0.0407012 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0406035 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0404332 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0402365 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0402088 |
| CALR | calreticulin | 0.0401165 |
| POTEF | POTE ankyrin domain family, member F | 0.040095 |
| PKM | pyruvate kinase, muscle | 0.0391609 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0388066 |
| PLAU | plasminogen activator, urokinase | 0.0375253 |
| MATR3 | matrin 3 | 0.0370353 |
| KRT8 | keratin 8, type II | 0.036872 |
| DIAPH1 | diaphanous-related formin 1 | 0.0367247 |
| CDC73 | cell division cycle 73 | 0.0364691 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0364314 |
| PCBP2 | poly(rC) binding protein 2 | 0.0362728 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0360819 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0359993 |
| KLF6 | Kruppel-like factor 6 | 0.0353904 |
| RBM39 | RNA binding motif protein 39 | 0.0350885 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0348518 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.034669 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0344223 |
| RPL3 | ribosomal protein L3 | 0.0344196 |
| ARRDC3 | arrestin domain containing 3 | 0.0337359 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0336126 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0335108 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0334103 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0332519 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0329265 |
| YBX1 | Y box binding protein 1 | 0.0327104 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.032678 |
| ABI1 | abl-interactor 1 | 0.0325574 |
| RPL19 | ribosomal protein L19 | 0.0325288 |
| TPM3 | tropomyosin 3 | 0.0324004 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0322916 |
| HELZ | helicase with zinc finger | 0.0320031 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0319025 |
| BRD2 | bromodomain containing 2 | 0.0316728 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0313537 |
| ATP11B | ATPase, class VI, type 11B | 0.0312297 |
| RIOK3 | RIO kinase 3 | 0.0312094 |
| MAP1B | microtubule-associated protein 1B | 0.030914 |
| OGA | O-GlcNAcase | 0.0304544 |
| MYO5B | myosin VB | 0.0301386 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0301026 |
| MYO1B | myosin IB | 0.029907 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0297224 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296802 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0294068 |
| DSPP | dentin sialophosphoprotein | 0.029389 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0290745 |
| FAM162A | family with sequence similarity 162, member A | 0.0290263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.145394 |
| HLA-B | major histocompatibility complex, class I, B | -0.131775 |
| CP | ceruloplasmin (ferroxidase) | -0.124112 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0979021 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0948438 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0915502 |
| LAMB3 | laminin, beta 3 | -0.0790077 |
| EFNA5 | ephrin-A5 | -0.0663031 |
| MMP7 | matrix metallopeptidase 7 | -0.0642021 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0582582 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0567662 |
| RNF213 | ring finger protein 213 | -0.052649 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0502633 |
| RAD51B | RAD51 paralog B | -0.0500455 |
| HLA-E | major histocompatibility complex, class I, E | -0.0493458 |
| HLA-A | major histocompatibility complex, class I, A | -0.0487769 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0477344 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0475166 |
| SP100 | SP100 nuclear antigen | -0.0470744 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0468801 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0442989 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0423989 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0417565 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0413432 |
| DTNA | dystrobrevin, alpha | -0.0410603 |
| EHBP1 | EH domain binding protein 1 | -0.0407195 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0403083 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0398866 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0382338 |
| APOL1 | apolipoprotein L, 1 | -0.0379017 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0377987 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0368298 |
| MX2 | MX dynamin-like GTPase 2 | -0.0367901 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0367601 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0365772 |
| MX1 | MX dynamin-like GTPase 1 | -0.0356719 |
| TBC1D22A | TBC1 domain family, member 22A | -0.035589 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0353499 |
| PCDH7 | protocadherin 7 | -0.0351804 |
| FBXO11 | F-box protein 11 | -0.0349602 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0347228 |
| RRBP1 | ribosome binding protein 1 | -0.0346316 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0344707 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.034252 |
| PHF3 | PHD finger protein 3 | -0.0336215 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0330513 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | -0.0328167 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0325863 |
| PRKCA | protein kinase C, alpha | -0.0323847 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.031976 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0318336 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0315681 |
| RIGI | RNA sensor RIG-I | -0.0308158 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0303081 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0298274 |
| BPTF | bromodomain PHD finger transcription factor | -0.0298167 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.029689 |
| SMYD3 | SET and MYND domain containing 3 | -0.0296827 |
| RAI14 | retinoic acid induced 14 | -0.0296497 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0293527 |
| MT1E | metallothionein 1E | -0.0291415 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0290609 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0290224 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0288045 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0285339 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0281015 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0280141 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.028 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0279006 |
| NABP1 | nucleic acid binding protein 1 | -0.027771 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0275548 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0275279 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0273705 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0273118 |
| RUNX1 | runt-related transcription factor 1 | -0.0268403 |
| HMGA2 | high mobility group AT-hook 2 | -0.0266547 |
| TMC5 | transmembrane channel-like 5 | -0.0263892 |
| EGFR | epidermal growth factor receptor | -0.026186 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0261636 |
| INTS6 | integrator complex subunit 6 | -0.0261148 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0258945 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0257629 |
| HM13 | histocompatibility (minor) 13 | -0.0256783 |
| RIN2 | Ras and Rab interactor 2 | -0.0256393 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0256383 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0254786 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0248814 |
| SYNRG | synergin, gamma | -0.024765 |
| CDK6 | cyclin-dependent kinase 6 | -0.0246189 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0245863 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0244699 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0244625 |
| TPM4 | tropomyosin 4 | -0.0243821 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0235313 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.023375 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0232431 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0231635 |
| PMP22 | peripheral myelin protein 22 | -0.023112 |
| GOLGB1 | golgin B1 | -0.0229813 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0228253 |
