| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Pitavastatin (Calcium) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Pitavastatin (Calcium)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HELZ | helicase with zinc finger | 0.098531 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0885746 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0785569 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0587671 |
| LPIN1 | lipin 1 | 0.0474698 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0472958 |
| XPO1 | exportin 1 | 0.0470713 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0448262 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0418363 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0392869 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.038969 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0370945 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0368792 |
| NDRG1 | N-myc downstream regulated 1 | 0.0340847 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0339472 |
| RHOA | ras homolog family member A | 0.0332623 |
| DTNA | dystrobrevin, alpha | 0.0325004 |
| PHIP | pleckstrin homology domain interacting protein | 0.0323943 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0322117 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0316544 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0313038 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0310398 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0307207 |
| PKM | pyruvate kinase, muscle | 0.0300696 |
| PTMA | prothymosin, alpha | 0.0297065 |
| POTEF | POTE ankyrin domain family, member F | 0.0295018 |
| QKI | QKI, KH domain containing, RNA binding | 0.0290853 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0290762 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0286775 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0282938 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0281239 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.027796 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0275134 |
| GOLGA4 | golgin A4 | 0.0274848 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0274192 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0265653 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0258712 |
| CASC3 | cancer susceptibility candidate 3 | 0.0258652 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0257279 |
| PTGES2 | prostaglandin E synthase 2 | 0.0256303 |
| WDR43 | WD repeat domain 43 | 0.0253635 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0253081 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0252583 |
| LMNA | lamin A/C | 0.0250186 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0249643 |
| COPA | coatomer protein complex, subunit alpha | 0.0249636 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0246815 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0245787 |
| FAM13A | family with sequence similarity 13, member A | 0.0245686 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0242783 |
| PTK2 | protein tyrosine kinase 2 | 0.0241607 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0241316 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0238434 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0238113 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0230087 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0229245 |
| TFG | TRK-fused gene | 0.0225758 |
| PDS5B | PDS5 cohesin associated factor B | 0.022304 |
| RNF145 | ring finger protein 145 | 0.0217467 |
| DENND4C | DENN/MADD domain containing 4C | 0.0216196 |
| RPL3 | ribosomal protein L3 | 0.0213667 |
| YTHDC1 | YTH domain containing 1 | 0.0212515 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.020762 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.020612 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0204995 |
| NCKAP1 | NCK-associated protein 1 | 0.0203042 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0202343 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0200637 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0198985 |
| MEMO1 | mediator of cell motility 1 | 0.0198575 |
| CDC73 | cell division cycle 73 | 0.0197964 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0197519 |
| SLMAP | sarcolemma associated protein | 0.0196468 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0192897 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0192299 |
| SEPTIN9 | septin 9 | 0.0192084 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0191793 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0191179 |
| PAPOLA | poly(A) polymerase alpha | 0.0189983 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0188291 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.018813 |
| ATP13A3 | ATPase type 13A3 | 0.0186842 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0186113 |
| MYOF | myoferlin | 0.0185134 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0184587 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0182522 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.018176 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0181346 |
| BBX | bobby sox homolog (Drosophila) | 0.0180635 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0179546 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0178781 |
| TLK2 | tousled-like kinase 2 | 0.0178779 |
| FMNL2 | formin-like 2 | 0.0178638 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0178545 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0177463 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0176721 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0175386 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0175268 |
| MEF2A | myocyte enhancer factor 2A | 0.017238 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0171763 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.202878 |
| IGF2 | insulin-like growth factor 2 | -0.201249 |
| LSAMP | limbic system-associated membrane protein | -0.141383 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.130008 |
| SYT1 | synaptotagmin I | -0.123091 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.105006 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.100441 |
| FMN1 | formin 1 | -0.0955374 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0863312 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0833214 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0784438 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0743251 |
| MEIS2 | Meis homeobox 2 | -0.0735549 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.071983 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0691611 |
| BPTF | bromodomain PHD finger transcription factor | -0.063489 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0614828 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0613271 |
| FRMD4A | FERM domain containing 4A | -0.0598193 |
| MAP1B | microtubule-associated protein 1B | -0.0584421 |
| GPC5 | glypican 5 | -0.0575529 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0564049 |
| NREP | neuronal regeneration related protein | -0.0543469 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0543277 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0539757 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0530847 |
| DPH6 | diphthamine biosynthesis 6 | -0.0522348 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0521273 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0520502 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0507525 |
| PLAT | plasminogen activator, tissue | -0.0504303 |
| KLHL13 | kelch-like family member 13 | -0.0502389 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0497359 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0493362 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0492206 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0486864 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0483597 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0480277 |
| PCDH9 | protocadherin 9 | -0.0459601 |
| RNF213 | ring finger protein 213 | -0.045788 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0445618 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0434887 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0433206 |
| SMYD3 | SET and MYND domain containing 3 | -0.0422445 |
| PRKCA | protein kinase C, alpha | -0.0422237 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0416237 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0415035 |
| ZNF804A | zinc finger protein 804A | -0.0404137 |
| ATRNL1 | attractin-like 1 | -0.0385725 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0383555 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0383324 |
| CADM2 | cell adhesion molecule 2 | -0.0380729 |
| CENPF | centromere protein F, 350/400kDa | -0.0373957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0369963 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0365641 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0361403 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0357714 |
| TLE4 | transducin-like enhancer of split 4 | -0.0357118 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0352833 |
| FHIT | fragile histidine triad | -0.0348411 |
| VCL | vinculin | -0.0345251 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0342441 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0331234 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0325348 |
| NBEA | neurobeachin | -0.0324824 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.032133 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0320773 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0316197 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0313019 |
| RAD51B | RAD51 paralog B | -0.0312132 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0311079 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0309572 |
| MBTD1 | mbt domain containing 1 | -0.0307324 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0305457 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0304815 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0298121 |
| ANGPT1 | angiopoietin 1 | -0.0297959 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.029233 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0290312 |
| STC1 | stanniocalcin 1 | -0.0289371 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0289098 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0285318 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0285173 |
| COL3A1 | collagen, type III, alpha 1 | -0.0282743 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.028269 |
| VIM | vimentin | -0.0281883 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0279834 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0279519 |
| PLPP1 | phospholipid phosphatase 1 | -0.0275843 |
| GLI3 | GLI family zinc finger 3 | -0.0275761 |
| ATM | ATM serine/threonine kinase | -0.0274872 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0274099 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0272847 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0272756 |
| B2M | beta-2-microglobulin | -0.0269322 |
| CEP350 | centrosomal protein 350kDa | -0.0263418 |
| PHF3 | PHD finger protein 3 | -0.0260728 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0260018 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258466 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0258252 |
